Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kaliappan Iyanar"'
Autor:
Kaliappan Iyanar, Jessica D. Dietz, Graciela B. Arhancet, Horng-Chih Huang, Danny J. Garland, Marcia I. Heron, Silvia I. Pomposiello, Xiao Hu, Len F. Lee, Joe T. Collins, Scott S. Woodard, James Robert Blinn, Maria A. Payne, Brenda L. Case, Rhonda S. Woerndle
Publikováno v:
Journal of Medicinal Chemistry. 53:5970-5978
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we
Autor:
Grace M. Wagner, Joe T. Collins, Scott S. Woodard, Randal E Numann, Kaliappan Iyanar, Graciela B. Arhancet, Danny J. Garland, James Robert Blinn, Jessica D. Dietz, Horng-Chih Huang, Xiao Hu
Publikováno v:
Journal of Medicinal Chemistry. 53:4300-4304
A number of known 1,4-dihydropyridine CCBs were identified as having comparable potency to the steroidal MR antagonist eplerenone. Chiral resolution of mebudipine revealed that MR and CCB activity reside in opposite enantiomers. Small molecule X-ray
Autor:
Kaliappan Iyanar, Robert W. Murray
Publikováno v:
Heteroatom Chemistry. 9:347-350
Some secondary amines of varying structural type have been oxidized by the methyltrioxorhenium/hydrogen peroxide system to the corresponding nitroxides in excellent yield. These results, coupled with our earlier work using this system, indicate the s
Autor:
Robert W. Murray, Kaliappan Iyanar
Publikováno v:
Tetrahedron Letters. 38:335-338
Methyltrioxorhenium catalyzes the oxidation of C 60 by hydrogen peroxide to give C 60 O. The reaction continues to produce C 60 O 2 and higher oxides. The yield of C 60 O represents a modest improvement over that given by other methods. The reaction
Publikováno v:
Tetrahedron Letters. 37:805-808
Methyltrioxorhenium catalyzes the reaction of hydrogen peroxide with organonitrogen compounds. The reactions are facile and high yield at room temperature or below. The observed chemistry is similar to that previously described by us using dimethyldi
Publikováno v:
Tetrahedron Letters. 36:6415-6418
Methyltrioxorhenium catalyzes the CH insertion reaction of hydrocarbons by hydrogen peroxide. In suitable substrates the reaction is stereospecific with retention.
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 27
Methyltrioxorhenium catalyzes the reaction of hydrogen peroxide with organonitrogen compounds. The reactions are facile and high yield at room temperature or below. The observed chemistry is similar to that previously described by us using dimethyldi
Publikováno v:
ChemInform. 28
Secondary amines are oxidized by the methyltrioxorhenium/hydrogen peroxide system to the corresponding nitrones in excellent yield. The results provide a further example of the parallel between the chemistry of this metal system and that of the dioxi
Autor:
Kaliappan Iyanar, Robert W. Murray
Publikováno v:
ChemInform. 29
Some secondary amines of varying structural type have been oxidized by the methyltrioxorhenium/hydrogen peroxide system to the corresponding nitroxides in excellent yield. These results, coupled with our earlier work using this system, indicate the s