Giant intracranial aneurysms: Natural history and 1-year case fatality after endovascular or surgical treatment

Autor: Dengler, Julius, Rüfenacht, Daniel, Meyer, Bernhard, Rohde, Veit, Endres, Matthias, Lenga, Pavlina, Uttinger, Konstantin, Rücker, Viktoria, Kursumovic, Adisa, Hong, Bujung, Mielke, Dorothee, Schmidt, Nils Ole, Burkhardt, Jan-Karl, Bijlenga, Philippe, Boccardi, Edoardo, Cognard, Christophe, Heuschmann, Peter U., Vajkoczy, Peter, Bauknecht, H.C., Bohner, G., Liebig, T., Wiener, E., Gläsker, S., Klingler, J.-H., Scheiwe, C., van Velthoven, V., Zentner, J., Durner, G., König, R., Pedro, M.T., Wirtz, R., Fiss, I., Kombos, T., Guhl, S., Schroeder, H.W.S., Strowitzki, M., Eicker, S., Steiger, H., Turowski, B., Abdulazim, A., Etminan, N., Haenggi, D., Kalff, R., Walter, J., Brawanski, A., Schebesch, K.M., Ardeshiri, A., Sure, Ulrich, Wrede, Karsten, Schmidt, N.O., Regelsberger, J., Westphal, M., Hosch, H., Moskopp, D., Hohaus, C., Meisel, H.J., Lehmberg, J., Wostrack, M., Ganslandt, O., Hopf, N., Musahl, C., Graewe, A., Meier, U., Krauss, J., Nakamura, M., Grote, A., Güresir, E., Schramm, J., Simon, M., Vatter, H., Rath, S.A., Boxhammer, E., Hoffmann, K.T., Diepers, M., Fandino, J., Marbacher, S., Familiari, P., Raco, A., Schaller, K., Gruber, A., Knosp, E., Wang, W.T., Rüfenacht, D.A., Wanke, I., Piano, M., Hernesniemi, J., Lehecka, M., Niemelä, M., Nurminen, V., Burkhardt, J.K., Bozinov, O., Maldaner, N., Regli, L., Eliava, S.S., Shekhtman, O.D., Helthuis, J., van Doormaal, T., van der Zwan, A., Dammers, R., Dirven, C.M.F., Gawlitza, M., Guenego, A., Fiedler, J., Kato, N., Murayama, Y., Dabus, G., Linfante, I., Starosciak, A.K., Miran, M.S., Suri, M.F.K.

Publikováno v: Journal of Neurosurgery, 134(1), 49-57. American Association of Neurological Surgeons
Journal of Neurosurgery (2019) pp. 1-9

OBJECTIVEClinical evidence on giant intracranial aneurysms (GIAs), intracranial aneurysms with a diameter of at least 25 mm, is limited. The authors aimed to investigate the natural history, case fatality, and treatment outcomes of ruptured and unrup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3798e01b83b1987a03dc9fa075b0d0
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Haem degradation products after subarachnoid haemorrhage cause long-term vasoconstriction and vessel wall thickening of extraparenchymal brain arteries in mice

Autor: Joerk, A, Schröder, SC, Ritter, M, Freitag, D, Ingrisch, I, Schulze, D, Pohnert, G, Westerhausen, M, Kalff, R, Witte, OW, Walter, J, Holthoff, K

Publikováno v: 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCV201 /20200626/

Objective: Delayed cerebral ischemia (DCI) caused by symptomatic cerebral vasospasm is the most important preventable cause of mortality and poor neurological outcome in subarachnoid haemorrhage (SAH) patients. We hypothesize that haem degradation pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa85de73b094c4672471c2bff819c834

Influence of an intracellular infection with Staphylococcus aureus on growth and cytokine secretion of glioblastoma cells and human astrocytes

Autor: Grube, S, Lemke, C, Tuchscherr, L, Ewald, C, Löffler, B, Kalff, R, Walter, J

Publikováno v: 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCP122 /20200626/

Objective: A relationship between postoperative infections and a prolonged survival in glioblastoma patients still remains controversial. The pathogens most frequently detected in this context are Staphylococcus species. Although the interaction of S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d3189352ccb10d2c887abe8e2a97dd

An orthotopic xenograft mouse model for benign human meningiomas

Autor: Freitag, D, Herrmann, KH, Reichenbach, JR, Ewald, C, Kalff, R, Walter, J

Publikováno v: 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCP130 /20200626/

Objective: Low-grade meningiomas are mainly characterized by their benign biological behavior, slow growth and low metabolic rates. Since the usual properties of malignant tumors, such as uncontrolled growth, tendency to migrate or infiltration, are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103b736255df89e234833ccd9a1293de

Defined glucose levels stimulate metabolic reprogramming and tumour progressive processes in human meningioma cells

Autor: Freitag, D, Huppertz, S, Kalff, R, Walter, J

Publikováno v: 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie; 20190512-20190515; Würzburg; DOCV244 /20190508/

Objective: In contrast to normal mammalian cells, which use oxygen to generate energy, cancer cells use glycolysis to generate energy due to their increased metabolism. This effect has an important role in carcinogenesis and tumor progression. The ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a161f1616feba68f8b958b16d63f1c0e