Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Kalevi Trontti"'
Autor:
Ying-Chieh Wu, Šárka Lehtonen, Kalevi Trontti, Riitta Kauppinen, Pinja Kettunen, Ville Leinonen, Markku Laakso, Johanna Kuusisto, Mikko Hiltunen, Iiris Hovatta, Kristine Freude, Hiramani Dhungana, Jari Koistinaho, Taisia Rolova
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Patients with Alzheimer's disease (AD) frequently present with cerebral amyloid angiopathy (CAA), characterized by the accumulation of beta-amyloid (Aβ) within the cerebral blood vessels, leading to cerebrovascular dysfunction. P
Externí odkaz:
https://doaj.org/article/ff2355ab447b4ba585cb169fd9c26369
Autor:
Ying Chieh Wu, Šarka Lehtonen, Kalevi Trontti, Ville Leinonen, Markku Laakso, Johanna Kuusisto, Mikko Hiltunen, Iiris Hovatta, Taisia Rolova, Jari Koistinaho
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S516-S517 (2023)
Externí odkaz:
https://doaj.org/article/3aaa8bfa59404b2e848499d424eb6120
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Anxiety is an evolutionarily conserved response that is essential for survival. Pathological anxiety, however, is a maladaptive response to nonthreatening situations and greatly affects quality of life. The recent COVID-19 pandemic has increased the
Externí odkaz:
https://doaj.org/article/7355de64079f4468b2ca6748a0ab62ba
Autor:
Henna Jäntti, Minna Oksanen, Pinja Kettunen, Stella Manta, Lionel Mouledous, Hennariikka Koivisto, Johanna Ruuth, Kalevi Trontti, Hiramani Dhungana, Meike Keuters, Isabelle Weert, Marja Koskuvi, Iiris Hovatta, Anni-Maija Linden, Claire Rampon, Tarja Malm, Heikki Tanila, Jari Koistinaho, Taisia Rolova
Publikováno v:
Cells, Vol 11, Iss 24, p 4116 (2022)
The PSEN1 ΔE9 mutation causes a familial form of Alzheimer’s disease (AD) by shifting the processing of amyloid precursor protein (APP) towards the generation of highly amyloidogenic Aβ42 peptide. We have previously shown that the PSEN1 ΔE9 muta
Externí odkaz:
https://doaj.org/article/32d6b7b081a84028b01d9a606f0770d8
Autor:
Jessica Mingardi, Luca La Via, Paolo Tornese, Giulia Carini, Kalevi Trontti, Mara Seguini, Daniela Tardito, Federica Bono, Chiara Fiorentini, Leonardo Elia, Iiris Hovatta, Maurizio Popoli, Laura Musazzi, Alessandro Barbon
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100381- (2021)
Converging clinical and preclinical evidence demonstrates that depressive phenotypes are associated with synaptic dysfunction and dendritic simplification in cortico-limbic glutamatergic areas. On the other hand, the rapid antidepressant effect of ac
Externí odkaz:
https://doaj.org/article/918673e220ed44929f78f6b4c70f4aa3
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Queen pheromones are used by eusocial insects to regulate all aspects of colony life. Here, Holman et al. compare the effects of queen pheromone on gene expression and splicing in four eusocial insect species, giving insight into the mechanism and ev
Externí odkaz:
https://doaj.org/article/17f7f80973994387834f18acd0b195f6
Autor:
Zuzanna Misiewicz, Stella Iurato, Natalia Kulesskaya, Laura Salminen, Luis Rodrigues, Giuseppina Maccarrone, Jade Martins, Darina Czamara, Mikaela A Laine, Ewa Sokolowska, Kalevi Trontti, Christiane Rewerts, Bozidar Novak, Naama Volk, Dong Ik Park, Eija Jokitalo, Lars Paulin, Petri Auvinen, Vootele Voikar, Alon Chen, Angelika Erhardt, Christoph W Turck, Iiris Hovatta
Publikováno v:
PLoS Genetics, Vol 15, Iss 9, p e1008358 (2019)
Stressful life events are major environmental risk factors for anxiety disorders, although not all individuals exposed to stress develop clinical anxiety. The molecular mechanisms underlying the influence of environmental effects on anxiety are large
Externí odkaz:
https://doaj.org/article/cc92368b12514335bdd3c2981c2821eb
Publikováno v:
PeerJ, Vol 6, p e5024 (2018)
Dispersal is a fundamental trait of a species’ biology. High dispersal results in weakly structured or even panmictic populations over large areas, whereas weak dispersal enables population differentiation and strong spatial structuring. We report
Externí odkaz:
https://doaj.org/article/eb05f8e9a0734ca9b3eb22bf849f07d8
Autor:
Kishor Dhaygude, Kalevi Trontti, Jenni Paviala, Claire Morandin, Christopher Wheat, Liselotte Sundström, Heikki Helanterä
Publikováno v:
PeerJ, Vol 5, p e3998 (2017)
Transcriptome resources for social insects have the potential to provide new insight into polyphenism, i.e., how divergent phenotypes arise from the same genome. Here we present a transcriptome based on paired-end RNA sequencing data for the ant Form
Externí odkaz:
https://doaj.org/article/3ff97ba2dd7442009e3fc54181aa1847
Autor:
Helena Johansson, Kishor Dhaygude, Stafva Lindström, Heikki Helanterä, Liselotte Sundström, Kalevi Trontti
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79777 (2013)
Social insects live in cooperative colonies, often in high densities and with closely related individuals, and interact using social contact behaviours. Compared to solitary insects, social insects have evolved multi-level immunity that includes immu
Externí odkaz:
https://doaj.org/article/77602b28045a4434a22c3705225da54a