Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kale Manoj Ganpat"'
Autor:
P. Ann Boriack-Sjodin, B. K. Kishore Reddy, Ramesh R. Kale, Vijaykamal Ahuja, Sunita M. de Sousa, Krishnan Malolanarasimhan, Sheshagiri Gaonkar, Anandkumar Raichurkar, Sreenivasaiah Menasinakai, Halesha D. Basavarajappa, Prashanti Madhavapeddi, M. R. Manjunatha, Shahul Hameed, David Waterson, Radha Nandishaiah, Vasan K. Sambandamurthy, C. N. Naveen Kumar, Derek Ogg, Vikas Shinde, Vaishali Humnabadkar, Krishna Koushik, Sreevalli Sharma, K. N. Mahesh Kumar, Sandeep R. Ghorpade, Kale Manoj Ganpat, Samit Ganguly, Lalit kumar Jena
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:870-879
Scaffold hopping from the thiazolopyridine ureas led to thiazolopyridone ureas with potent antitubercular activity acting through inhibition of DNA GyrB ATPase activity. Structural diversity was introduced, by extension of substituents from the thiaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f597532256fbaf9317ffdec02a7322
https://doi.org/10.1016/j.bmcl.2013.12.080
https://doi.org/10.1016/j.bmcl.2013.12.080
Autor:
John Breen, Minli Zhang, Kishore Reddy, Matthew D. Miller, Jeroen C. Verheijen, Sushmita D. Lahiri, Pravin S. Shirude, Tiffany Palmer, Sharon Tentarelli, Kale Manoj Ganpat, Mark Zambrowski
We present a comprehensive study of C6-alkylidene containing oxapenems. We show that this class of β-lactamase inhibitors possesses an unprecedented spectrum with activity against class A, C, and D enzymes. Surprisingly, this class of compounds disp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7850ce841723882bd3d91f0f310123b5
https://europepmc.org/articles/PMC4137382/
https://europepmc.org/articles/PMC4137382/
Autor:
Vikas Shinde, Vasan K. Sambandamurthy, Sowmya Bharath, Ragini Singh, Sudhir Landge, Sreenivasaiah Menasinakai, Kakoli Mukherjee, Anirban Ghosh, Anandkumar Raichurkar, Jyothi Bhat, C. Bjorkelid, Vikas Patil, B. K. Kishore Reddy, Naveen Kumar, Aishwarya Sundaram, Balachandra Bandodkar, Kaveri Das, Krishnan Malolanarasimhan, Sudha Ravishankar, Vasanthi Ramachandran, T. Alwyn Jones, Subramanyam J. Tantry, Parvinder Kaur, Ragadeepthi Tunduguru, Anisha Ambady, Naina Vinay Mudugal, Kale Manoj Ganpat
Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenate, the first committed and rate-limiting step toward coenzyme A (CoA) biosynthesis. In our earlier reports, we had established that the type I isoform encoded by the coaA gene is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4f3e4256aa802b61732e793f93831e
https://europepmc.org/articles/PMC4068421/
https://europepmc.org/articles/PMC4068421/
Autor:
Kale Manoj Ganpat, Dwarakanath Prahlad, P. Shahul Hameed, B. Bhaskar, Santosh Nandan, Vikas Patil, Anandkumar Raichurkar, Meenakshi Balganesh
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(9)
Novel triazolopyrimidine acylsulfonamides class of antimycobacterial agents, which are mycobacterial acetohydroxyacid synthase (AHAS) inhibitors were designed by hybridization of known AHAS inhibitors such as sulfonyl urea and triazolopyrimidine sulf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39041d52ff1be031d4e9a7c1f2b3f9a2
https://pubmed.ncbi.nlm.nih.gov/24703230
https://pubmed.ncbi.nlm.nih.gov/24703230
Autor:
Sunita M. de Sousa, C. N. Naveen Kumar, Anandkumar Raichurkar, Kale Manoj Ganpat, Krishna Koushik, M. R. Manjunatha, David Waterson, Vasan K. Sambandamurthy, Vikas Shinde, K. N. Mahesh Kumar, Jitendar Reddy, Julie A. Tucker, Prashanti Madhavapeddi, Derek Ogg, Sandeep R. Ghorpade, Shubhada Barde, Halesha D. Basavarajappa, Shahul Hameed P, Samit Ganguly, V. K. Ramya, Lalit kumar Jena, Vijender Panduga, Vijaykamal Ahuja, Prakash Vachaspati, David C. McKinney, Jayashree Giridhar, Anirban Ghosh, Sheshagiri Gaonkar, Supreeth Guptha, P. Ann Boriack-Sjodin, Suresh Rudrapatna, Sreevalli Sharma, Usha Kranthi, Vaishali Humnabadkar
Publikováno v:
Journal of medicinal chemistry. 56(21)
A pharmacophore-based search led to the identification of thiazolopyridine ureas as a novel scaffold with antitubercular activity acting through inhibition of DNA Gyrase B (GyrB) ATPase. Evaluation of the binding mode of thiazolopyridines in a Mycoba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97722b62636e6c49a04e6567ae3fc13
https://pubmed.ncbi.nlm.nih.gov/24088190
https://pubmed.ncbi.nlm.nih.gov/24088190