The evolution of A beta peptide burden in the APP23 transgenic mice: implications for A beta deposition in Alzheimer disease

Autor: Yu-Min Kuo, Beach, Tg, Sue, Li, Scott, S., Layne, Kj, Kokjohn, Ta, Kalback, Wm, Luehrs, Dc, Vishnivetskaya, Ta, Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Weller, Ro, Roher, Ae

Publikováno v: ResearcherID

BACKGROUND: High levels of A beta in the cerebral cortex distinguish demented Alzheimer's disease (AD) from nondemented elderly individuals, suggesting that decreased amyloid-beta (A beta) peptide clearance from the brain is a key precipitating facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c347bdab8a97ad2cf7862c49758fb46d
https://europepmc.org/articles/PMC1950067/

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Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease.

Autor: Maarouf CL; The Longtine Center for Neurodegenerative Biochemistry, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Kokjohn TA; Department of Microbiology, Midwestern University, Glendale, Arizona, United States of America., Walker DG; Laboratory of Neuroinflammation, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Whiteside CM; The Longtine Center for Neurodegenerative Biochemistry, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Kalback WM; The Longtine Center for Neurodegenerative Biochemistry, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Whetzel A; Laboratory of Neuroinflammation, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Sue LI; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Serrano G; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Jacobson SA; Cleo Roberts Center for Clinical Research, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Sabbagh MN; Cleo Roberts Center for Clinical Research, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Reiman EM; Banner Alzheimer's Institute, Phoenix, Arizona, United States of America., Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Roher AE; The Longtine Center for Neurodegenerative Biochemistry, Banner Sun Health Research Institute, Sun City, Arizona, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Aug 28; Vol. 9 (8), pp. e105784. Date of Electronic Publication: 2014 Aug 28 (Print Publication: 2014).

Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.

Autor: Roher AE; The Longtine Center for Neurodegenerative Biochemistry, Banner Sun Health Research Institute Sun City, AZ 85351., Maarouf CL, Malek-Ahmadi M, Wilson J, Kokjohn TA, Daugs ID, Whiteside CM, Kalback WM, Macias MP, Jacobson SA, Sabbagh MN, Ghetti B, Beach TG

Publikováno v: American journal of neurodegenerative disease [Am J Neurodegener Dis] 2013 Sep 18; Vol. 2 (3), pp. 187-207. Date of Electronic Publication: 2013 Sep 18 (Print Publication: 2013).