Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kalanethee Paul-Pletzer"'
Autor:
Leslie S. Jimenez, Philip G. Williams, Takeshi Yamamoto, Jianjie Ma, Noriaki Ikemoto, Hiromi Morimoto, Kalanethee Paul-Pletzer, Jerome Parness
Publikováno v:
Biochemical Journal. 387:905-909
Dantrolene is an inhibitor of intracellular Ca2+ release from skeletal muscle SR (sarcoplasmic reticulum). Direct photoaffinity labelling experiments using [3H]azidodantrolene and synthetic domain peptides have demonstrated that this drug targets ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f885a409f8d1ffb0a84cf8fe982acc0
https://doi.org/10.1042/bj20041336
https://doi.org/10.1042/bj20041336
Autor:
Jerome Parness, Kalanethee Paul-Pletzer, Leslie S. Jimenez, Hiromi Morimoto, Sanjay S. Palnitkar
Publikováno v:
Biochemistry. 40:531-542
Dantrolene is a skeletal muscle relaxant which acts by inhibiting intracellular Ca(2+) release from sarcoplasmic reticulum (SR). It is used primarily in the treatment of malignant hyperthermia (MH), a pharmacogenetic sensitivity to volatile anestheti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9bc9f5e7b747c9025199470b7dd6d0
https://doi.org/10.1021/bi001502s
https://doi.org/10.1021/bi001502s
Autor:
Kalanethee Paul-Pletzer, Edward E. Farmer, Philippe Reymond, Rudolf Grimm, Beatrice Kunz, Christoph Eckerskorn
Publikováno v:
The Plant Cell. 8:2265-2276
Oligogalacturonides are structural and regulatory homopolymers from the extracellular pectic matrix of plants. In vitro micromolar concentrations of oligogalacturonates and polygalacturonates were shown previously to stimulate the phosphorylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1389ec4e2966f5116d20d94c55a5995b
https://doi.org/10.1105/tpc.8.12.2265
https://doi.org/10.1105/tpc.8.12.2265
Autor:
Philip G. Williams, Manjunatha B. Bhat, Noriaki Ikemoto, Takeshi Yamamoto, Jerome Parness, Kalanethee Paul-Pletzer, Leslie S. Jimenez, Jianjie Ma, Hiromi Morimoto
Publikováno v:
The Journal of biological chemistry. 277(38)
Dantrolene is a drug that suppresses intracellular Ca(2+) release from sarcoplasmic reticulum (SR) in skeletal muscle and is used as a therapeutic agent in individuals susceptible to malignant hyperthermia. Although its precise mechanism of action ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fde25a8b5981fc73f856fdade4fdfcf
https://pubmed.ncbi.nlm.nih.gov/12167662
https://pubmed.ncbi.nlm.nih.gov/12167662
Publikováno v:
Analytical biochemistry. 289(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80792cdcfb332c7049f86bd52d1783e
https://pubmed.ncbi.nlm.nih.gov/11161301
https://pubmed.ncbi.nlm.nih.gov/11161301
Autor:
Bin Bin, Jerome Parness, H. Morimoto, Leslie S. Jimenez, P. G. Williams, Kalanethee Paul-Pletzer, Sanjay S. Palnitkar
Publikováno v:
Journal of medicinal chemistry. 42(11)
Dantrolene sodium is a medically important hydantoin derivative that interferes with release of Ca2+ from intracellular stores of skeletal muscle by an unknown mechanism. Identification of the molecular target of dantrolene would greatly aid in under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b76ff5060f583a7631fab5a6be73f67
https://pubmed.ncbi.nlm.nih.gov/10354395
https://pubmed.ncbi.nlm.nih.gov/10354395
Autor:
Kalanethee Paul-Pletzer
Publikováno v:
Drugs of Today. 42:559
Interleukin (IL)-6 contributes to a myriad of physiologic and pathophysiologic processes. Among its many physiologic functions, IL-6 plays an active role in immunology, inflammatory responses, bone metabolism, arthritis and neoplasia. Overproduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266ff0a3ecfcc229f7d2dcc40ed55121
https://doi.org/10.1358/dot.2006.42.9.1025692
https://doi.org/10.1358/dot.2006.42.9.1025692