Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kala M Levine"'
Autor:
Sara E Martin del Campo, Nicholas Latchana, Kala M Levine, Valerie P Grignol, Ene T Fairchild, Alena Cristina Jaime-Ramirez, Thao-Vi Dao, Volodymyr I Karpa, Mary Carson, Akaansha Ganju, Anthony N Chan, William E Carson
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115919 (2015)
Metastatic melanoma is the most aggressive form of this cancer. It is important to understand factors that increase or decrease metastatic activity in order to more effectively research and implement treatments for melanoma. Increased cell invasion t
Externí odkaz:
https://doaj.org/article/e933a813097f473383a31a84b1474c33
Autor:
Elizabeth A. Streacker, Thomas Olencki, Volodymyr Karpa, Kala M. Levine, William E. Carson, Lorena P. Suarez-Kelly, Joseph Markowitz, Sara E. Martin del Campo, Taylor R. Brooks, Kari Kendra, Anissa Bingman, Susan Geyer
Publikováno v:
Cancer Immunology, Immunotherapy
Melanoma is a highly immunogenic tumor and consequently, efforts have been centered on the development of immune-based treatments for this malignancy [1]. Interferons were initially described in the mid-1950s as proteins that interfere with viral rep
Autor:
Andrew Stiff, Bhuvaneswari Ramaswamy, Prashant Trikha, Maryam B. Lustberg, Raquel E. Reinbolt, Robert Wesolowski, Rachel M. Layman, Kala M. Levine, Ewa Mrozek, John C. Byrd, Erin Macrae, Thomas A. Mace, Mahmoud Abdel-Rasoul, William E. Carson, Megan C. Duggan, Michael A. Caligiuri, Lynn Schoenfield, Joseph Markowitz
Publikováno v:
Cancer Immunology, Immunotherapy. 66:1437-1447
This study sought to evaluate whether myeloid-derived suppressor cells (MDSC) could be affected by chemotherapy and correlate with pathologic complete response (pCR) in breast cancer patients receiving neo-adjuvant chemotherapy. Peripheral blood leve
Autor:
Amanda Campbell, Akaansha Ganju, Stephen V. Liu, Sarvani Uppati, Kala M. Levine, Bonnie Paul, Tiffany Noel, Elizabeth L. McMichael, Gonzalo N. Olaverria Salavaggione, Panos Savvides, William E. Carson, Melanie E. Davis, Lakhvir S. Atwal, Michael A. Caligiuri, Theodoros N. Teknos, Nicholas B. Courtney, Thomas Olencki, Kallan Williams, Megan C. Duggan, Brooke Benner, Susheela Tridandapani, Kyle A. Martin, Xiaokui Mo, John C. Byrd
Publikováno v:
Clin Cancer Res
Purpose: mAbs including cetuximab can induce antibody-dependent cellular cytotoxicity (ADCC) and cytokine production mediated via innate immune cells with the ability to recognize mAb-coated tumors. Preclinical modeling has shown that costimulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fcefe11987d7a560074b271108d065
https://europepmc.org/articles/PMC6697573/
https://europepmc.org/articles/PMC6697573/
Autor:
Neela Bhave, Kala M. Levine, Amanda Campbell, Kallan S. Opheim, Tiffany Noel, Lianbo Yu, Megan C. Duggan, Elizabeth L. McMichael, Michelle C. Culbertson, WE Carson rd
Publikováno v:
OncoImmunology, Vol 7, Iss 2 (2018)
Natural killer (NK) cells serve a critical role in the immune response against microbes and developing tumors. We have demonstrated that NK cells produce stimulatory cytokines (e.g., IFN-γ) in response to potent stimulation via immobilized IgG (to e
Autor:
Michael A. Caligiuri, Gregory B. Lesinski, Prashant Trikha, Manisha H. Shah, Amir Mortazavi, Kala M. Levine, Bonnie Paul, William E. Carson, Thomas A. Mace, Sri Vidya Kondadasula, Susan McClory, Ene T. Fairchild, Kristan D. Guenterberg, Bethany L. Mundy-Bosse, John C. Byrd, Valerie P. Grignol, Volodymyr Karpa, Xueliang Pan, Susheela Tridandapani, Alena Cristina Jaime-Ramirez, Joseph Markowitz, Sara E. Martin del Campo, Amanda Campbell, J. Paul Monk, Thomas Olencki
Publikováno v:
The Journal of Immunology. 195:1995-2005
Sorafenib is an oral multikinase inhibitor that was originally developed as a Raf kinase inhibitor. We hypothesized that sorafenib would also have inhibitory effects on cytokine signaling pathways in immune cells. PBMCs from normal donors were treate
Autor:
J. Harrison Howard, Naduparambil K. Jacob, Kala M. Levine, Zachary B. Abrams, William E. Carson, Tanios Bekaii-Saab, Lai Wei, Joseph Markowitz, Kelly Regan, John N Hassani, Gregory B. Lesinski, Xiaoli Zhang, Taylor R. Brooks, Kari Kendra, Thomas Olencki, Nicholas Latchana, Sarvani Uppati, Philip R. O. Payne
Publikováno v:
OncoTargets and therapy
Joseph Markowitz,1–4 Zachary Abrams,2,5 Naduparambil K Jacob,2,6 Xiaoli Zhang,2,7 John N Hassani,1 Nicholas Latchana,8 Lai Wei,2,7 Kelly E Regan,2,5 Taylor R Brooks,2 Sarvani R Uppati,2 Kala M Levine,2 Tanios Bekaii-Saab,2,4 Kari L Kendra,2,4 Grego
Autor:
Thao-Vi Dao, Sara E. Martin del Campo, William E. Carson, Alena Cristina Jaime-Ramirez, Mary Y. Carson, Nicholas Latchana, Kala M. Levine, Valerie P. Grignol, Anthony N. Chan, Akaansha Ganju, Volodymyr Karpa, Ene T. Fairchild
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 1, p e0115919 (2015)
PLoS ONE, Vol 10, Iss 1, p e0115919 (2015)
Metastatic melanoma is the most aggressive form of this cancer. It is important to understand factors that increase or decrease metastatic activity in order to more effectively research and implement treatments for melanoma. Increased cell invasion t
Autor:
Elizabeth L. McMichael, Panayiotis Savvides, Tiffany Noel, Kala M. Levine, Bonnie Paul, Akansha Gansu, William E. Carson, Melanie E. Davis, Theodoros N. Teknos, Thomas Olencki, Megan C. Duggan, Kallan S. Opheim, Stephen V. Liu, Amanda Campbell, Gonzalo N. Olaverria Salavaggione, Lakhvir S. Atwal, Sarvani Uppati
Publikováno v:
Cancer Research. 76:CT143-CT143
Introduction: Preclinical investigations demonstrated that IL-12 significantly enhances the lytic actions and cytokine production of NK cells against cetuximab-coated HER1-positive SCCHN cell lines via synergistic activation of the MAP kinase pathway
Autor:
Gregory B. Lesinski, Sarvani Uppati, Xiaoli Zhang, Joseph Markowitz, Zachary B. Abrams, William E. Carson, Naduparambil K. Jacob, Lai Wei, Taylor R. Brooks, Nicholas Latchana, Kala M. Levine, Philip R. O. Payne, Thomas Olencki, Kari Kendra, Tanios Bekaii-Saab
Publikováno v:
Journal of Clinical Oncology. 33:e22065-e22065
e22065 Background: miRNAs are short 19-22 non-coding RNAs that function to repress translation of mRNA transcripts and contribute to the development of cancer. We hypothesized that miRNA array base...