Complete set of the Atg8-E1-E2-E3 conjugation machinery forms an interaction web that mediates membrane shaping.

Autor: Alam JM; Institute of Microbial Chemistry (BIKAKEN), Tokyo, Japan., Maruyama T; Institute of Microbial Chemistry (BIKAKEN), Tokyo, Japan., Noshiro D; Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan., Kakuta C; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan., Kotani T; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan., Nakatogawa H; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Noda NN; Institute of Microbial Chemistry (BIKAKEN), Tokyo, Japan. nn@igm.hokudai.ac.jp.; Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan. nn@igm.hokudai.ac.jp.

Publikováno v: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Jan; Vol. 31 (1), pp. 170-178. Date of Electronic Publication: 2023 Dec 06.

Efficacy and Safety of Cilostazol in Mild Cognitive Impairment: A Randomized Clinical Trial.

Autor: Saito S; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan., Suzuki K; Innovation Center for Translational Research, National Center for Geriatrics and Gerontology, Obu, Japan., Ohtani R; Department of Neurology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan., Maki T; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Kowa H; Division of Neurology, Kobe University Hospital, Kobe, Japan., Tachibana H; Division of Neurology, Kobe University Hospital, Kobe, Japan., Washida K; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan., Kawabata N; Division of Neurology, Yachiyo Hospital, Anjo, Japan., Mizuno T; Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Kanki R; Department of Neurology, Osaka City General Hospital, Osaka, Japan., Sudoh S; Department of Neurology, National Hospital Organization, Utano National Hospital, Kyoto, Japan., Kitaguchi H; Department of Neurology, Kurashiki Central Hospital, Kurashiki, Japan., Shindo K; Department of Neurology, Kurashiki Central Hospital, Kurashiki, Japan., Shindo A; Department of Neurology, Graduate School of Medicine, Mie University, Tsu, Japan., Oka N; Department of Neurology, National Hospital Organization Minami Kyoto Hospital, Joyo, Japan., Yamamoto K; Internal Medicine and Neurology, Nara Midori Clinic, Nara, Japan., Yasuno F; Department of Psychiatry, National Center for Geriatrics and Gerontology, Obu, Japan., Kakuta C; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan., Kakuta R; Department of Data Science, National Cerebral and Cardiovascular Center, Suita, Japan., Yamamoto Y; Department of Molecular Innovation in Lipidemiology, National Cerebral and Cardiovascular Center, Suita, Japan., Hattori Y; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan., Takahashi Y; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan., Nakaoku Y; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Tonomura S; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Oishi N; Department of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Aso T; Laboratory for Brain Connectomics Imaging, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan., Taguchi A; Department of Regenerative Medicine Research, Institute of Biomedical Research and Innovation, Kobe, Japan., Kagimura T; Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan., Kojima S; Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan., Taketsuna M; Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan., Tomimoto H; Department of Neurology, Graduate School of Medicine, Mie University, Tsu, Japan., Takahashi R; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Fukuyama H; Research and Educational Unit of Leaders for Integrated Medical System, Kyoto University, Kyoto, Japan., Nagatsuka K; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan., Yamamoto H; Department of Data Science, National Cerebral and Cardiovascular Center, Suita, Japan., Fukushima M; Foundation of Learning Health Society Institute, Nagoya, Japan., Ihara M; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.

Publikováno v: JAMA network open [JAMA Netw Open] 2023 Dec 01; Vol. 6 (12), pp. e2344938. Date of Electronic Publication: 2023 Dec 01.

[Development of the Japanese version of the 16-Item Informant Questionnaire on Cognitive Decline for the Elderly (J-IQCODE 16) for the Diagnosis of Prestroke Dementia].

Autor: Egashira S; Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center.; Department of Neurology, National Cerebral and Cardiovascular Center., Tanaka K; Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center.; Division of Stroke Care Unit, National Cerebral and Cardiovascular Center., Oka A; Department of Nursing of Stroke Care Unit, National Cerebral and Cardiovascular Center., Nagasawa Y; Department of Nursing of Stroke Care Unit, National Cerebral and Cardiovascular Center., Kohama K; Department of Nursing of Stroke Care Unit, National Cerebral and Cardiovascular Center., Tokunaga A; Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center., Ohata A; Department of Rehabilitation, National Cerebral and Cardiovascular Center., Kakuta C; Department of Neurology, National Cerebral and Cardiovascular Center., Funabiki Y; Graduate School of Human and Environmental Studies, Kyoto University., Toyoda K; Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center., Ihara M; Department of Neurology, National Cerebral and Cardiovascular Center., Koga M; Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center.

Publikováno v: Rinsho shinkeigaku = Clinical neurology [Rinsho Shinkeigaku] 2023 May 27; Vol. 63 (5), pp. 275-285. Date of Electronic Publication: 2023 Apr 25.

GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER.

Autor: Matsumoto S; Faculty of Life Sciences, Kyoto Sangyo University, Kyoto, Japan.; Institute for Protein Dynamics, Kyoto Sangyo University, Kyoto, Japan.; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Japan., Ono S; Faculty of Life Sciences, Kyoto Sangyo University, Kyoto, Japan.; Institute for Protein Dynamics, Kyoto Sangyo University, Kyoto, Japan., Shinoda S; Faculty of Life Sciences, Kyoto Sangyo University, Kyoto, Japan., Kakuta C; Faculty of Life Sciences, Kyoto Sangyo University, Kyoto, Japan., Okada S; Department of Biochemistry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Ito T; Department of Biochemistry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Numata T; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Japan., Endo T; Faculty of Life Sciences, Kyoto Sangyo University, Kyoto, Japan.; Institute for Protein Dynamics, Kyoto Sangyo University, Kyoto, Japan.

Publikováno v: The Journal of cell biology [J Cell Biol] 2022 Jun 06; Vol. 221 (6). Date of Electronic Publication: 2022 Apr 20.

Comparing Pathological Risk Factors for Dementia between Cognitively Normal Japanese and Americans.

Autor: Cui C; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Higashiyama A; Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.; Department of Hygiene, Wakayama Medical University, Wakayama 641-0011, Japan., Lopresti BJ; Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Ihara M; Department of Neurology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan., Aizenstein HJ; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA., Watanabe M; Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan., Chang Y; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA., Kakuta C; Department of Neurology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan., Yu Z; Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Mathis CA; Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Kokubo Y; Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan., Fukuda T; Department of Radiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan., Villemagne VL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA., Klunk WE; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Lopez OL; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Kuller LH; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Miyamoto Y; Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.; Open Innovation Center, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan., Sekikawa A; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Publikováno v: Brain sciences [Brain Sci] 2021 Sep 08; Vol. 11 (9). Date of Electronic Publication: 2021 Sep 08.