Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kakuji Torigoe"'
Autor:
Kenji Nakanishi, Kouji Tominaga, Kiyoshi Matsui, Haruki Okamura, Masashi Kurimoto, Toshikazu Hada, Tomohiro Yoshimoto, Kakuji Torigoe
Publikováno v:
International Immunology. 12:151-160
IL-18 is a proinflammatory cytokine that plays an important role in NK cell activation and T(h)1 response. IL-18 has a structural homology to IL-1, particularly IL-1beta. IL-18R, composed of IL-1R-related protein (IL-18Ralpha) and IL-1R accessory pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4070d10674cc01a23684bbd9dc084067
https://doi.org/10.1093/intimm/12.2.151
https://doi.org/10.1093/intimm/12.2.151
Autor:
Kakuji Torigoe, Masashi Kurimoto, Mark Micallef, Tadao Tanimoto, Yoshihiro Nishida, Hakuo Ikegami, Keizo Kohno
Publikováno v:
Cancer Immunology, Immunotherapy. 48:109-117
Interleukin-18 (IL-18) enhances interferon gamma (IFNgamma) production and natural killer (NK) cell activity, and elicits protective antitumor effects in vivo. IL-18 and IL-12 synergistically augment IFNgamma production reportedly because IL-12 enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4700839ac9b4e9234707b68ebcc074
https://doi.org/10.1007/s002620050554
https://doi.org/10.1007/s002620050554
Autor:
Kakuji Torigoe, Yasushi Aizawa, Yoshihiro Nishida, Tetsuya Mori, Masao Ikeda, Hakuo Ikegami, Tadao Tanimoto, Takanori Okura, Hiroshi Yamauchi, Masashi Kurimoto
Publikováno v:
Hybridoma. 17:577-580
We have recently reported the successful purification and characterization of the human interleukin 18 (IL-18) receptor (R) using a monoclonal antibody (MAb) of the IgM kappa class (117-10C) after immunizing mice with cells of the Hodgkin's disease-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6088536b9094cdf9fd89cd81fdf9f9f
https://doi.org/10.1089/hyb.1998.17.577
https://doi.org/10.1089/hyb.1998.17.577
Autor:
Hakuo Ikegami, Masashi Kurimoto, Takanori Okura, Kakuji Torigoe, Shimpei Ushio, Hiroshi Yamauchi, Masao Ikeda, Toshio Kunikata, Chie Ushio
Publikováno v:
Cellular Immunology. 189:135-143
Interleukin-18 (IL-18) was identified as a molecule that induces IFN-gamma production and enhances NK cell cytotoxicity. Characterization of the receptor for human IL-18 (hIL-18R) is important for investigating the physiological role of IL-18 in natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a622b92dd6c61a446c22b5692c362484
https://doi.org/10.1006/cimm.1998.1376
https://doi.org/10.1006/cimm.1998.1376
Autor:
Toshio Kunikata, Hirotada Kojima, Shimpei Ushio, Takanori Okura, Masashi Kurimoto, Mitsukiyo Fujii, Osamu Sanou, Hakuo Ikegami, Susumu Kobayashi, Tadatoshi Murakami, Kakuji Torigoe, Madoka Taniai, Tsunetaka Ohta, Masao Ikeda
Publikováno v:
Journal of Biological Chemistry. 272:25737-25742
Interleukin (IL)-18 was identified as a molecule that induces IFN-γ production and enhances NK cell cytotoxicity. In this paper, we report upon the purification and characterization of human IL-18 receptor (hIL-18R). We selected the Hodgkin’s dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef41e4401927783baf9a252467fe2ad
https://doi.org/10.1074/jbc.272.41.25737
https://doi.org/10.1074/jbc.272.41.25737
Autor:
Haruki Okamura, Hiroko Tsutsui, Toshinori Komatsu, Masuo Yutsudo, Akira Hakura, Tadao Tanimoto, Kakuji Torigoe, Takanori Okura, Yoshiyuki Nukada, Kazuko Hattori, Kenji Akita, Motoshi Namba, Fujimi Tanabe, Kaori Konishi, Shigeharu Fukuda, Masashi Kurimoto
Publikováno v:
Nature. 378:88-91
The mechanism underlying the differentiation of CD4+ T cells into functionally distinct subsets (Th1 and Th2) is incompletely understood, and hitherto unidentified cytokines may be required for the functional maturation of these cells. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ee420b4e883c314ba80be07987103a
https://doi.org/10.1038/378088a0
https://doi.org/10.1038/378088a0
Autor:
Hiroshi Yamauchi, Shouji Furusako, Kazuo Fushimi, Kakuji Torigoe, Masayoshi Namba, Masashi Kurimoto
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 34(6)
To develop a new gene therapy model for cancer, a clonal cell line (KMST-6/TNF) which produces human tumor necrosis factor alpha (hTNF-alpha) has been developed by introducing hTNF-alpha cDNA into a human immortal fibroblast cell line (KMST-6). The c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ec4c6972eb35748d940514c807052d
https://pubmed.ncbi.nlm.nih.gov/9661049
https://pubmed.ncbi.nlm.nih.gov/9661049
Autor:
Kenji Akita, Motoshi Namba, Masao Ikeda, Rohko Takakura-Yamamoto, Michael S.-S. Su, Tadao Tanimoto, Michiyo Satoh-Itoh, Kouzo Yamamoto, Yoshiyuki Nukada, Keizo Kohno, Mitsukiyo Fujii, Yong Gu, Takanori Okura, Kakuji Torigoe, Masashi Kurimoto, Takashi Ohtsuki
Publikováno v:
The Journal of biological chemistry. 272(42)
Recently, human interleukin 18 (hIL-18) cDNA was cloned, and the recombinant protein with a tentatively assigned NH2-terminal amino acid sequence was generated. However, natural hIL-18 has not yet been isolated, and its cellular processing is therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba59beb7f1c850f23174f9ce66c838bc
https://pubmed.ncbi.nlm.nih.gov/9334240
https://pubmed.ncbi.nlm.nih.gov/9334240
Autor:
Masashi Kurimoto, Keizo Kohno, Mark Micallef, Kakuji Torigoe, Kenshi Yoshida, Mitsukiyo Fujii, Toshiharu Hanaya, Masao Ikeda, Tadao Tanimoto, Sachiko Kawai, Shigeyuki Arai
Publikováno v:
Cancer immunology, immunotherapy : CII. 43(6)
Interferon-gamma-inducing factor/interleukin-18 is a novel cytokine that reportedly augments natural killer (NK) activity in human and mouse peripheral blood mononuclear cell cultures in vitro and has recently been designated IL-18. In this study, IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb577c2accc08f7c3f21d6ec254cebf2
https://pubmed.ncbi.nlm.nih.gov/9067408
https://pubmed.ncbi.nlm.nih.gov/9067408
Autor:
Motoshi Namba, Masashi Kurimoto, Shigeharu Fukuda, Masao Ikeda, Kakuji Torigoe, Mark Micallef, Tadao Tanimoto, Keizo Kohno, Takashi Ohtsuki, Fujimi Tanabe, Shimpei Ushio, Mitsukiyo Fujii
Publikováno v:
European journal of immunology. 26(7)
The novel cytokine interferon-gamma-inducing factor (IGIF) augments natural killer (NK) cell activity in cultures of human peripheral blood mononuclear cells (PBMC), similarly to the structurally unrelated cytokine interleukin (IL)-12. IGIF has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2150740ec480fda5fd654bdd57c59d
https://pubmed.ncbi.nlm.nih.gov/8766574
https://pubmed.ncbi.nlm.nih.gov/8766574