Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kakia Nikolaou"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 337-342 (2021)
Background: Increasing scientific evidence shows the significant role of epigenetic mechanisms in drug use disorder, abstinence and relapse. Studies on human subjects are limited compared to those on animals, for various reasons such as poly-substanc
Externí odkaz:
https://doaj.org/article/42592080465b4effa9abace89f025150
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 337-342 (2021)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Opioid abstinence for 21 days does not affect global DNA methylation levels in white blood cells. • All participants in the study completed a 21-day “dry” detoxification program. • Findings do not rule o
Highlights • Opioid abstinence for 21 days does not affect global DNA methylation levels in white blood cells. • All participants in the study completed a 21-day “dry” detoxification program. • Findings do not rule o
Autor:
Kakia Nikolaou
Publikováno v:
Suchttherapie. 19:132-139
ZusammenfassungDer Flüchtlingsstatus verstärkt die Vulnerabilität höchst gefährdeter Menschen, die Pre-Migrations-Traumata und Post-Migrations-Stress ausgesetzt sind. Die Auswirkungen des Migrationsstresses spiegeln sich wieder in der Entwicklun
Autor:
Leda, Kovatsi, Kakia, Nikolaou
Publikováno v:
Vitamins and hormones. 111
The neuropeptide Oxytocin (ΟΤ) is involved as a neurohormone, a neurotransmitter, or a neuromodulator in an extensive range of central and peripheral effects, complex emotional and social human behaviors, memory and learning processes. It is implic
Autor:
Kakia Nikolaou, Leda Kovatsi
The neuropeptide Oxytocin (ΟΤ) is involved as a neurohormone, a neurotransmitter, or a neuromodulator in an extensive range of central and peripheral effects, complex emotional and social human behaviors, memory and learning processes. It is implic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77bd0e83f008b7f9ac41f6c14b271276
https://doi.org/10.1016/bs.vh.2019.05.003
https://doi.org/10.1016/bs.vh.2019.05.003
Publikováno v:
Journal of psychoactive drugs. 49(3)
Pre-clinical studies show that, following chronic opioid exposure, oxytocin neurons exhibit over-excitation upon withdrawal, causing an increase in oxytocin brain and plasma levels. Relevant clinical data on humans are scarce. This study investigates
Publikováno v:
The American journal of drug and alcohol abuse. 41(6)
Opioids influence bone metabolism in several ways and osteoporosis associated with the long-term use of opioids is believed to be multifactorial.To investigate the effect of opioid dependence on conventional and novel biochemical parameters of bone m
Autor:
Samuel Njau, Aristidis Tsatsakis, Domniki Fragou, George Karakiulakis, Leda Kovatsi, Spyros Batzios, Eleni Papakonstantinou, Kakia Nikolaou
Publikováno v:
Toxicology mechanisms and methods. 23(5)
Context: Although opiate abuse is known to affect matrix metalloproteinases (MMPs), data on these enzymes and their tissue inhibitors in heroin addicts are scarce.In the present study, we determined serum concentrations of MMP-2, MMP-9, tissue inhibi
Autor:
Theodora Papamitsou, Kakia Nikolaou, Konstantina Topouridou, George Koliakos, Leda Kovatsi, Samuel Njau
Publikováno v:
The American journal of drug and alcohol abuse. 36(4)
Background: Opiate abuse has been linked to oxidative stress, through the separate evaluation of oxidants and antioxidants. Objectives: To determine prooxidant–antioxidant balance (PAB) in chronic heroin users in a single assay, easily applied in a
Autor:
Kakia Nikolaou, Alexandra Tsolakidou, Leda Kovatsi, Samuel Njau, Katerina Thisiadou, Ioannis Karamouzis
Publikováno v:
The American journal of drug and alcohol abuse. 36(1)
Although chronic heroin abuse has been extensively linked to oxidative stress, and while plasma 15-F(2t)-IsoP is considered a good indicator of oxidative stress, there remain few references in the literature about the plasma concentration of this mar