Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kakeru Shimoda"'
Autor:
Caroline Sunggip, Kakeru Shimoda, Sayaka Oda, Tomohiro Tanaka, Kazuhiro Nishiyama, Supachoke Mangmool, Akiyuki Nishimura, Takuro Numaga-Tomita, Motohiro Nishida
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cardiac hypertrophy, induced by neurohumoral factors, including angiotensin II and endothelin-1, is a major predisposing factor for heart failure. These ligands can induce hypertrophic growth of neonatal rat cardiomyocytes (NRCMs) mainly through Ca2+
Externí odkaz:
https://doaj.org/article/a4753e6a469d4c0698a6960a9822ea14
Autor:
Kazuhiro, Nishiyama, Akiyuki, Nishimura, Kakeru, Shimoda, Tomohiro, Tanaka, Yuri, Kato, Takahiro, Shibata, Hiroshi, Tanaka, Hitoshi, Kurose, Yasu-Taka, Azuma, Hideshi, Ihara, Yoshito, Kumagai, Takaaki, Akaike, Philip, Eaton, Koji, Uchida, Motohiro, Nishida
Publikováno v:
Science signaling. 15(716)
After ligand stimulation, many G protein–coupled receptors (GPCRs) undergo β-arrestin–dependent desensitization, during which they are internalized and either degraded or recycled to the plasma membrane. Some GPCRs are not subject to this type o
Autor:
Kazuhiro Nishiyama, Makoto Tsuda, Caroline Sunggip, Yuri Kato, Tomoya Ito, Tomohiro Tanaka, Akiyuki Nishimura, Kakeru Shimoda, Hidetoshi Tozaki-Saitoh, Motohiro Nishida
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Cardiac tissue remodeling caused by hemodynamic overload is a major clinical outcome of heart failure. Uridine-responsive purinergic P2Y6 receptor (P2Y6R) contributes to the progression of cardiovascular remodeling in rodents, but it is not known whe
Autor:
Kakeru, Shimoda, Akiyuki, Nishimura, Caroline, Sunggip, Tomoya, Ito, Kazuhiro, Nishiyama, Yuri, Kato, Tomohiro, Tanaka, Hidetoshi, Tozaki-Saitoh, Makoto, Tsuda, Motohiro, Nishida
Publikováno v:
Scientific Reports
Cardiac tissue remodeling caused by hemodynamic overload is a major clinical outcome of heart failure. Uridine-responsive purinergic P2Y6 receptor (P2Y6R) contributes to the progression of cardiovascular remodeling in rodents, but it is not known whe
Autor:
Akiyuki Nishimura, Tomohiro Tanaka, Kakeru Shimoda, Shota Sasaki, Toshiro Kaneko, Motohiro Nishida
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2-O
Autor:
Akiyuki Nishimura, Tang Xiaokang, Kakeru Shimoda, Yuri Kato, Kazuhiro Nishiyama, Motohiro Nishida
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:3-B
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1-S10
Autor:
Kakeru Shimoda
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:1-B
Autor:
Caroline Sunggip, Takuro Numaga-Tomita, Kakeru Shimoda, Makoto Tsuda, Akiyuki Nishimura, Motohiro Nishida
Publikováno v:
Pharmacological Research. 120:51-59
Aging has a remarkable effect on cardiovascular homeostasis and it is known as the major non-modifiable risk factor in the development of hypertension. Medications targeting sympathetic nerve system and/or renin-angiotensin-aldosterone system are wid
Autor:
Kazuhiro Nishiyama, Tomohiro Tanaka, Kakeru Shimoda, Akiyuki Nishimura, Daiju Yamazaki, Takashi Toyama, Yasunari Kanda, Yasuhiro Shinkai, Takuro Numaga-Tomita, Takaaki Akaike, Yoshito Kumagai, Motohiro Nishida
Publikováno v:
Science signaling. 12(587)
Chronic exposure to methylmercury (MeHg), an environmental electrophilic pollutant, reportedly increases the risk of human cardiac events. We report that exposure to a low, non-neurotoxic dose of MeHg precipitated heart failure induced by pressure ov