Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Kakar Sham S"'
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 532 (2012)
Abstract Background Pituitary tumor-transforming gene (PTTG) is an oncogene that is overexpressed in variety of tumors and exhibits characteristics of a transforming gene. Previous transgenic mouse models to access the tumorigenic potential in the pi
Externí odkaz:
https://doaj.org/article/090d4e54a8ff4372b7fdd134b934e28b
Publikováno v:
Journal of Ovarian Research, Vol 4, Iss 1, p 17 (2011)
Abstract Background Ovarian cancer is the leading cause of death from gynecologic cancer in women worldwide. According to the National Cancer Institute, ovarian cancer has the highest mortality rate among all the reproductive cancers in women. Advanc
Externí odkaz:
https://doaj.org/article/ba98d63e46084d2a85457ef5fa0c7fca
Autor:
Panguluri Siva K, Kakar Sham S
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 577 (2009)
Abstract Background Pituitary tumor transforming gene (PTTG), also known as securin, is highly expressed in various tumors including pituitary, thyroid, colon, ovary, testis, lung, and breast. An overexpression of PTTG enhances cell proliferation, in
Externí odkaz:
https://doaj.org/article/097cd03e841944cd9e4bec598071f336
Autor:
Fong Miranda Y, Kakar Sham S
Publikováno v:
Journal of Ovarian Research, Vol 2, Iss 1, p 12 (2009)
Abstract Development of mouse models representing human spontaneous ovarian cancer has been hampered by the lack of understanding of the etiology of this very complex disease. Mouse models representing the different types of ovarian cancer are needed
Externí odkaz:
https://doaj.org/article/ea15a68b6a904277a62b8d33f55ff64c
Publikováno v:
Journal of Ovarian Research, Vol 2, Iss 1, p 11 (2009)
Abstract MicroRNAs (miRNAs) represent a class of small non-coding RNAs that control gene expression by targeting messenger RNA (mRNA). Recently, it has been demonstrated that miRNA expression is altered in many human diseases including cancers, sugge
Externí odkaz:
https://doaj.org/article/9c4a49c98e354ad2a6c19e6f9bc341b6
Publikováno v:
Journal of Ovarian Research, Vol 1, Iss 1, p 1 (2008)
Externí odkaz:
https://doaj.org/article/05ee49c000ab403fa08d46371ac974d2
Publikováno v:
Journal of Ovarian Research, Vol 1, Iss 1, p 6 (2008)
Abstract Pituitary tumor transforming gene (PTTG), also known as securin is an important gene involved in many biological functions including inhibition of sister chromatid separation, DNA repair, organ development, and expression and secretion of an
Externí odkaz:
https://doaj.org/article/b4f54cfd8e4d4d97bb0aacf77bd6978c
Autor:
Bronstein Marcello D, Giannella-Neto Daniel, Passos Vanessa Q, Perez-Millán María I, Goya Rodolfo G, Kakar Sham S, Díaz-Torga Graciela S, Cristina Carolina, Becu-Villalobos Damasia
Publikováno v:
Molecular Cancer, Vol 6, Iss 1, p 4 (2007)
Abstract Background Pituitary tumor transforming gene (pttg) is a novel oncogene that is expressed at higher level in most of the tumors analyzed to date compared to normal tissues. Nevertheless, its expression in prolactinomas and its relation with
Externí odkaz:
https://doaj.org/article/42b2fc2a2e094b7dbe9420aff44361a8
Autor:
Kakar Sham S, Malik Mohammad T
Publikováno v:
Molecular Cancer, Vol 5, Iss 1, p 61 (2006)
Abstract Background Pituitary tumor transforming gene (PTTG) is a novel oncogene that is expressed at higher level in most of the tumors analyzed to date compared to normal tissues. Existence of a relationship between PTTG levels and tumor angiogenes
Externí odkaz:
https://doaj.org/article/3ad07e2bc3724b3c925090b4b35ae33c
Publikováno v:
Molecular Cancer, Vol 4, Iss 1, p 3 (2005)
Abstract Background Pituitary tumor transforming gene1 (PTTG1) is a novel oncogene that is expressed in most tumors. It encodes a protein that is primarily involved in the regulation of sister chromatid separation during cell division. The oncogenic
Externí odkaz:
https://doaj.org/article/9ee0a942cf58440b923ee2d352d1e354