Výsledky vyhledávání - "Kajsa Lindell"

Hypertension in Obesity and the Leptin Receptor Gene Locus1

Autor: Yvon C. Chagnon, Monique Chagnon, Göran Holm, Kajsa Lindell, Claude Bouchard, Per Björntorp, Roland Rosmond, Björn Carlsson, Louis Pérusse

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 85:3126-3131

Recent animal studies indicate that leptin is involved in the regulation of blood pressure through the leptin receptor. Therefore, 51-yr-old men (N = 284) were selected; and anthropometric, endocrine, metabolic, and hemodynamic variables were examine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a3a42a5ca9fbcd6b7dfb123fa24cf26
https://doi.org/10.1210/jcem.85.9.6781

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Cyclical Variations in the Abundance of Leptin Receptors, but not in Circulating Leptin, Correlate with NPY Expression during the Oestrous Cycle

Autor: Lena M. S. Carlsson, Carole Wilson, Kajsa Lindell, Iain C. A. F. Robinson, Björn Carlsson, Pamela A. Bennett

Publikováno v: Neuroendocrinology. 69:417-423

We have demonstrated previously that pharmacological doses of oestradiol decreased leptin receptor expression in the hypothalamus. We therefore analysed leptin receptor expression during the oestrous cycle in the rat, to establish if acute changes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ec2f68ba815b282579ea9cf3e162bb
https://doi.org/10.1159/000054444

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Human Adipose Tissue Expresses Angiotensinogen and Enzymes Required for Its Conversion to Angiotensin II1

Autor: Björn Carlsson, Kajsa Lindell, Lars Sjöström, Cecilia Karlsson, Malin Ottosson, Lena M. S. Carlsson

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 83:3925-3929

Angiotensin II regulates blood pressure and may affect adipogenesis and adipocyte metabolism. Angiotensin II is produced by cleavage of angiotensinogen by renin and angiotensin-converting enzyme in the circulation. In addition, angiotensin II may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d7ed715e6a431bbfab1736a6e09b746
https://doi.org/10.1210/jcem.83.11.5276

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Expression of Functional Leptin Receptors in the Human Ovary1

Autor: Kajsa Lindell, Lena M. S. Carlsson, Håkan Billig, Eva Ch Svensson, Christina Bergh, Björn Carlsson, Peter Lind, Cecilia Karlsson

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 82:4144-4148

The size of body fat stores is known to influence fertility, indicating a link between adipose tissue and the reproductive system. Studies in mice have identified the adipocyte-derived hormone, leptin (Ob protein), as a possible mediator of this effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ed23c21c596f9a74cd843ec2e03a3b6
https://doi.org/10.1210/jcem.82.12.4446

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Selective introduction of antisense oligonucleotides into single adult CNS progenitor cells using electroporation demonstrates the requirement of STAT3 activation for CNTF-induced gliogenesis

Autor: Peter S. Eriksson, Maria A I Åberg, Frida Ryttsén, Lars Rosengren, A. J. MacLennan, Björn Carlsson, Kajsa Lindell, Owe Orwar, Gunnel Hellgren

Publikováno v: Molecular and cellular neurosciences. 17(3)

We have developed a novel method in which antisense DNA is selectively electroporated into individual adult neural progenitor cells. By electroporation of antisense oligonucleotides against signal transducer and activator of transcription 3 (STAT3) w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4552cab9d76056e39b4cc3ef98b290e1
https://pubmed.ncbi.nlm.nih.gov/11273640

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Leptin receptor 5'untranslated regions in the rat: relative abundance, genomic organization and relation to putative response elements

Autor: Kajsa Lindell, Yoshiaki Itoh, Lena M. S. Carlsson, Pamela A. Bennett, Iain C.A.F. Robinson, Björn Carlsson

Publikováno v: Molecular and cellular endocrinology. 172(1-2)

Hypothalamic sensitivity to leptin has been suggested to be important for regulation of body fat mass. Mice heterozygous for a mutation in the leptin receptor (leptin-R) have an increased body fat mass suggesting that the abundance of leptin-R may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399e662a560e2a86138c74c733c3a20f
https://pubmed.ncbi.nlm.nih.gov/11165038

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Differential expression and regulation of leptin receptor isoforms in the rat brain: effects of fasting and oestrogen

Autor: Björn Carlsson, Cecilia Karlsson, Pamela A. Bennett, Iain C. A. F. Robinson, Kajsa Lindell, Lena M. S. Carlsson

Publikováno v: Neuroendocrinology. 67(1)

Leptin affects body weight and reproduction mainly via receptors in the central nervous system. Different isoforms of the leptin receptor (leptin-R) exist, including a long isoform (leptin-RL) with signalling capacity and short isoforms (leptin-RS) w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a3b6da06dfa878ff04324155217ab7
https://pubmed.ncbi.nlm.nih.gov/9485166

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Obese (ob) gene defects are rare in human obesity

Autor: Lars Sjöström, Ulla Karlsson, Björn Carlsson, Kajsa Lindell, Cecilia Karlsson, Otto Westphal, Ragnar Bjarnason, Lena M. S. Carlsson, Britt G. Gabrielsson

Publikováno v: Scopus-Elsevier

Our knowledge of the role of the recently cloned ob-protein (leptin) in the regulation of body fat stores is largely derived from experiments performed in mice. Different mouse models exhibit abnormalities in ob-gene expression, with extreme overexpr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8253495f0c98d13cf9df963a1cb4ac18
https://pubmed.ncbi.nlm.nih.gov/9061713

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