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pro vyhledávání: '"Kaja Kolmančič"'
Publikováno v:
Life, Vol 12, Iss 5, p 640 (2022)
Treatment with levodopa (L-dopa) in Parkinson’s disease (PD) leads to involuntary movements termed L-dopa-induced dyskinesia (LID). There are contradictory data about the influence of hormone therapy in female PD patients with LID and of 17-β-estr
Externí odkaz:
https://doaj.org/article/3bddc2f5df78458487dbdbb1d6da7211
Autor:
Kaja Kolmančič, Nina K. Zupančič, Maja Trošt, Dušan Flisar, Milica G. Kramberger, Zvezdan Pirtošek, Maja Kojović
Publikováno v:
Movement Disorders. 37:1465-1473
With the progression of Parkinson's disease (PD), pulsatile treatment with oral levodopa causes maladaptive changes within basal ganglia-thalamo-cortical circuits, which are clinically expressed as motor fluctuations and dyskinesias. At the level of
Publikováno v:
Bosnian Journal of Basic Medical Sciences
Bosnian Journal of Basic Medical Sciences (2021)
Bosnian Journal of Basic Medical Sciences (2021)
Parkinson’s disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. Dopamine precursor levodopa (L-dopa) is used as the first-line treatment for PD. Evidence suggests neuroprotective eff