Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kaizhou Yan"'
Autor:
Yao Zhou, Kaizhou Yan, Qijian Qin, Olawale G. Raimi, Chao Du, Bin Wang, Chukwuemeka Samson Ahamefule, Bartosz Kowalski, Cheng Jin, Daan M. F. van Aalten, Wenxia Fang
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Aspergillus fumigatus is a devastating opportunistic fungal pathogen causing hundreds of thousands of deaths every year. Phosphoglucose isomerase (PGI) is a glycolytic enzyme that converts glucose-6-phosphate to fructose-6-phosphate, a key p
Externí odkaz:
https://doaj.org/article/35b7683a45a5434ca20a82b41dcf8cdb
Autor:
Kaizhou Yan, Mathew Stanley, Bartosz Kowalski, Olawale G. Raimi, Andrew T. Ferenbach, Pingzhen Wei, Wenxia Fang, Daan M.F. van Aalten
Publikováno v:
The Journal of biological chemistry. 298(6)
Aspergillus fumigatus is the causative agent of invasive aspergillosis, an infection with mortality rates of up to 50%. The glucan-rich cell wall of A. fumigatus is a protective structure that is absent from human cells and is a potential target for
Autor:
Bartual, Sergio G., Wenfan Wei, Yao Zhou, Pravata, Veronica M., Wenxia Fang, Kaizhou Yan, Ferenbach, Andrew T., Lockhart, Deborah E. A., van Aalten, Daan M. F.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/28/2021, Vol. 118 Issue 39, p1-10, 10p
Autor:
Yao Zhou, Wenxia Fang, Andrew T. Ferenbach, Veronica M. Pravata, Deborah E. A. Lockhart, Sergio G. Bartual, Daan M. F. van Aalten, Wenfan Wei, Kaizhou Yan
Publikováno v:
'Proceedings of the National Academy of Sciences of the USA ', vol: 118, pages: e2110298118-1-e2110298118-10 (2021)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Aspergillus fumigatus gives rise to invasive aspergillosis in immunocompromised individuals. The rise of A. fumigatus antifungal resistance threatens a limited arsenal of treatment options. Here, we use genetic and molecular approaches t