Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Kaizhou Jin"'
Autor:
Saimeng Shi, Duancheng Guo, Longyun Ye, Tianjiao Li, Qinglin Fei, Mengxiong Lin, Xianjun Yu, Kaizhou Jin, Weiding Wu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-18 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant digestive tract tumor with limited clinical treatments. Transforming acidic coiled-coil-containing protein 3 (TACC3) is a component of the centrosome axis and a member of the TACC
Externí odkaz:
https://doaj.org/article/9a85e684f5cb4e558f07329aad902170
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pancreatic cancer has an exclusive inhibitory tumor microenvironment characterized by a dense mechanical barrier, profound infiltration of immunosuppressive cells, and a lack of penetration of effector T cells, which constitute an important cause for
Externí odkaz:
https://doaj.org/article/a974b5823063411a86e9c2da995ff961
Autor:
Longyun Ye, Kaizhou Jin, Zhenyu Liao, Zhiwen Xiao, Huaxiang Xu, Xuan Lin, Hao Li, Tianjiao Li, Wuhu Zhang, Xuan Han, Wenquan Wang, Heli Gao, Liang Liu, Weiding Wu, Xianjun Yu
Publikováno v:
EBioMedicine, Vol 79, Iss , Pp 104016- (2022)
Summary: Background: Previously, we uncovered a patient subgroup with highly malignant pancreatic cancer with serum markers CEA+/CA125+/CA19-9 ≥ 1000 U/mL (triple-positive, TP). However, the underlying immunosuppressive mechanism in the tumor immun
Externí odkaz:
https://doaj.org/article/5ac80511a6ba49eda212ca5b9c13eb6d
Autor:
Yitao Gong, Yunzhen Qian, Guopei Luo, Yu Liu, Ruijie Wang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Weiding Wu, Chen Liu
Publikováno v:
World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-8 (2021)
Abstract Background Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which plays a pivotal role in the progression of pancreatic ductal adenocarcinoma (PDAC). Theref
Externí odkaz:
https://doaj.org/article/97b2d54f28c84ea58371efd07c86e3b6
Autor:
Yunzhen Qian, Yitao Gong, Zhiyao Fan, Guopei Luo, Qiuyi Huang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2020)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by a poor prognosis and high mortality rate. Genetic mutations and altered molecular pathways serve as targets in precise therapy. Using next-generation sequencing (NGS),
Externí odkaz:
https://doaj.org/article/5010a92b482e48ba911dd2d523f4cf37
Autor:
He Cheng, Guopei Luo, Kaizhou Jin, Zhiyao Fan, Qiuyi Huang, Yitao Gong, Jin Xu, Xianjun Yu, Chen Liu
Publikováno v:
Cancer Medicine, Vol 9, Iss 6, Pp 2153-2159 (2020)
Abstract Purpose Kras mutation and abnormal immune status are associated with pancreatic cancer development and progression. In this study, we evaluated the Kras mutation status in circulating tumor DNA and circulating T cell subsets in a cohort of a
Externí odkaz:
https://doaj.org/article/ebf03e4209fe483f865398b6b8184cb5
Autor:
Kun Fan, Zhiyao Fan, He Cheng, Qiuyi Huang, Chao Yang, Kaizhou Jin, Guopei Luo, Xianjun Yu, Chen Liu
Publikováno v:
Cancer Medicine, Vol 8, Iss 13, Pp 5903-5915 (2019)
Abstract Gemcitabine (GEM) is the standard chemotherapy drug for pancreatic cancer. Because of widespread drug resistance, the effect is limited. Therefore, it is urgent to reveal the underlying mechanism. Glycolysis is the most remarkable character
Externí odkaz:
https://doaj.org/article/34a2f127293e4649a4686c8fa3ee246a
Autor:
Zhiyao Fan, He Cheng, Kaizhou Jin, Yitao Gong, Qiuyi Huang, Jin Xu, Quanxing Ni, Xianjun Yu, Chen Liu, Guopei Luo
Publikováno v:
World Journal of Surgical Oncology, Vol 17, Iss 1, Pp 1-8 (2019)
Abstract Background Both the 7th and 8th editions of the American Joint Committee on Cancer (AJCC) staging systems have been introduced for pancreatic adenocarcinoma. However, the applicability of these classifications for invasive intraductal papill
Externí odkaz:
https://doaj.org/article/973196a123634d8faaafc1db77eeb53e
Autor:
Yitao Gong, Zhiyao Fan, Guopei Luo, Chao Yang, Qiuyi Huang, Kun Fan, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Apoptosis resistance is to a large extent a major obstacle leading to chemotherapy failure during cancer treatment. Bypassing the apoptotic pathway to induce cancer cell death is considered to be a promising approach to overcoming this probl
Externí odkaz:
https://doaj.org/article/ac73ba75946446469c7e217973f8aa35
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3748 (2022)
Common pancreatic diseases have caused significant economic and social burdens worldwide. The interstitial microenvironment is involved in and plays a crucial part in the occurrence and progression of pancreatic diseases. Innate lymphoid cells (ILCs)
Externí odkaz:
https://doaj.org/article/3150ed1137c74aa6a98124256454059e