Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Kaizheng Gong"'
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Purpose Glycolysis and immune metabolism play important roles in acute myocardial infarction (AMI). Therefore, this study aimed to identify and experimentally validate the glycolysis-related hub genes in AMI as diagnostic biomarkers, and fur
Externí odkaz:
https://doaj.org/article/66ac211661da46e8a30b5a8d527c4bdd
Autor:
Fang Ye, Xin Pan, Zhiyi Zhang, Xufu Xiang, Xinyu Li, Binghao Zhang, Peiruo Ning, Aijun Liu, Qinggong Wang, Kaizheng Gong, Jiancheng Li, Lizhe Zhu, Chungen Qian, Geng Chen, Yang Du
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114895- (2024)
Summary: Hydroxycarboxylic acid receptor 3 (HCAR3), a class A G-protein-coupled receptor, is an important cellular energy metabolism sensor with a key role in the regulation of lipolysis in humans. HCAR3 is deeply involved in many physiological proce
Externí odkaz:
https://doaj.org/article/a2ebab9f3ae24ce5a8734c1f30ab6ece
Autor:
Xin Pan, Fang Ye, Peiruo Ning, Zhiyi Zhang, Xinyu Li, Binghao Zhang, Qian Wang, Geng Chen, Wei Gao, Chen Qiu, Zhangsong Wu, Jiancheng Li, Lizhe Zhu, Jiang Xia, Kaizheng Gong, Yang Du
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract Hydroxycarboxylic acid receptor 2 (HCAR2) belongs to the family of class A G protein-coupled receptors with key roles in regulating lipolysis and free fatty acid formation in humans. It is deeply involved in many pathophysiological processes
Externí odkaz:
https://doaj.org/article/8c6f33326a9245ae978c5009f4185e6c
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Intimal hyperplasia (IH) is a prominent pathological event that occurs during in-stent restenosis and atherosclerosis. Ferroptosis, characterized by iron-dependent and lipid peroxidation, has become the recent focus of studies on the occurrence and p
Externí odkaz:
https://doaj.org/article/8290c888b9a2469eae89bb1dfc1dced2
Publikováno v:
PeerJ, Vol 10, p e13436 (2022)
Background Intimal hyperplasia is a common pathological process of restenosis following angioplasty, atherosclerosis, pulmonary hypertension, vein graft stenosis, and other proliferative diseases. This study aims to screen for potential novel gene ta
Externí odkaz:
https://doaj.org/article/622cd1fa84d6473a93418a5ce4aea37f
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 910 (2022)
Deubiquitinating enzymes (DUBs) are a group of proteases that are important for maintaining cell homeostasis by regulating the balance between ubiquitination and deubiquitination. As the only known metalloproteinase family of DUBs, JAB1/MPN/Mov34 met
Externí odkaz:
https://doaj.org/article/4762bff562244a448d53dcade1b463c3
Autor:
Kaizheng Gong, Mingxing Chen, Rujun Li, Yanghong He, Huajiang Zhu, Dan Yao, Suzanne Oparil, Zhengang Zhang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 40, Iss 5, Pp 908-920 (2016)
Background: We have recently demonstrated that activated transforming growth factor-β (TGF-β) signaling suppresses myocardial peroxisome proliferator-activated receptor γ (PPARγ) expression in the pressure overloaded heart. In this study, we aim
Externí odkaz:
https://doaj.org/article/a649822b27a2453599fbfeedd164e36f
Autor:
Xinkai Qu, Weiyi Fang, Kaizheng Gong, Jianding Ye, Shaofeng Guan, Ruogu Li, Yingjia Xu, Yan Shen, Min Zhang, Hua Liu, Wenhui Xie
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98242 (2014)
Accurate assessment of coronary chronic total occlusion (CTO) lesion is essential to design an appropriate procedural strategy before revascularization. The present study aims to evaluate the significance of a single multislice computed tomography (M
Externí odkaz:
https://doaj.org/article/a5b7552a70f243c199981c036bbf00cc
Autor:
Dongqi Xing, Suzanne Oparil, Hao Yu, Kaizheng Gong, Wenguang Feng, Jonathan Black, Yiu-Fai Chen, Susan Nozell
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36890 (2012)
BackgroundNFκB signaling is critical for expression of genes involved in the vascular injury response. We have shown that estrogen (17β-estradiol, E2) inhibits expression of these genes in an estrogen receptor (ER)-dependent manner in injured rat c
Externí odkaz:
https://doaj.org/article/e4fa65d4a16842978a7d03be9c2cb870
Autor:
Dongqi Xing, Kaizheng Gong, Wenguang Feng, Susan E Nozell, Yiu-Fai Chen, John C Chatham, Suzanne Oparil
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24021 (2011)
We have shown that glucosamine (GlcN) or O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc) treatment augments O-linked-N-acetylglucosamine (O-GlcNAc) protein modification and attenuates inflammatory mediator expression, le
Externí odkaz:
https://doaj.org/article/a7f2dc0860774d3f89264b507a9cdf13