Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kaiwu Xu"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Background By complexing poly (ADP-ribose) (PAR) in reaction to broke strand, PAR polymerase1 (PARP1) acts as the key enzyme participated in DNA repair. However, recent studies suggest that unrepaired DNA breaks results in persistent PARP1 a
Externí odkaz:
https://doaj.org/article/2dbbc65cf70e40c7b4a544e46fcc9342
Autor:
Changjiang Qin, Zhiyu Ji, Ertao Zhai, Kaiwu Xu, Yijie Zhang, Quanying Li, Hong Jing, Xiaoliang Wang, Xinming Song
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-8 (2022)
Abstract The use of PARP inhibitors in combination with radiotherapy is a promising strategy to locally enhance DNA damage in tumors. Loss of XRCC2 compromises DNA damage repairs, and induced DNA damage burdens may increase the reliance on PARP-depen
Externí odkaz:
https://doaj.org/article/8483d3384d244135a2e3c5d34d47dfb3
Autor:
Kaiming Wu, Jun Ma, Yanfeng Zhan, Kuanzhi Liu, Ziyin Ye, Jianhui Chen, Kaiwu Xu, Hongli Huang, Yulong He
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 2, Pp 545-554 (2018)
Background/Aims: Colon cancer, also known as colorectal cancer (CRC), is one of the most common malignant tumors globally. Although significant advances have been made for developing novel therapeutics, the mechanisms of progression of colorectal can
Externí odkaz:
https://doaj.org/article/25103134806949a480c3bde36c481db6
Publikováno v:
Asian Journal of Surgery, Vol 43, Iss 9, Pp 955-956 (2020)
Externí odkaz:
https://doaj.org/article/c882ef50f0db42a7bb92144b09fcc9a8
Publikováno v:
Asian Journal of Surgery, Vol 43, Iss 8, Pp 840-841 (2020)
Externí odkaz:
https://doaj.org/article/1b62138da2dd4f49822d6fa543f70183
Publikováno v:
Gastroenterology Research and Practice, Vol 2014 (2014)
Objective. Preoperative radio(chemo)therapy (pR(C)T) appears to increase postoperative complications of rectal cancer resection, but clinical trials have reported conflicting results. The objective of this meta-analysis was performed to assess the ef
Externí odkaz:
https://doaj.org/article/a8810e3ca9f2497f8a9421e454014983
Publikováno v:
Chirurgia. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fdd89320fe74bfbb7e6bda5681aba32
https://doi.org/10.23736/s0394-9508.20.05183-9
https://doi.org/10.23736/s0394-9508.20.05183-9
Publikováno v:
Immunobiology. 227(2)
To investigate the mechanism of lncRNA OGFRP1 affecting angiogenesis and epithelial-mesenchymal transition (EMT) in colorectal cancer (CRC) and provide a new target for the treatment of CRC.The expressions of OGFRP1, miR-423-5p, and CTCF were measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce36377b26fb241cd46cb4d874a7f67b
https://pubmed.ncbi.nlm.nih.gov/35066433
https://pubmed.ncbi.nlm.nih.gov/35066433
Autor:
Hong Yang, Zhihui Chen, Hui Ren, Jia Liu, Li Ding, Yulong He, Kaiwu Xu, Ertao Zhai, Zhimei Zhang, Weixin Xiong, Xinming Song, Liang Yang
Publikováno v:
Human Pathology. 84:62-70
Solute carrier family 17 member 9 (SLC17A9) is a member of the family of transmembrane proteins that are involved in the transport of small molecules. The role of SLC17A9 in colorectal cancer (CRC) remains poorly understood. The present study aimed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aeb5477de455013bd93ac45ba880ade
https://doi.org/10.1016/j.humpath.2018.09.002
https://doi.org/10.1016/j.humpath.2018.09.002
Autor:
Yi-Jie Zhang, Hong Jing, Quanying Li, Er-Tao Zhai, Changjiang Qin, Zhiyu Ji, Xinming Song, Kaiwu Xu
Background: Loss of XRCC2 compromises DNA damage repairs, and induced DNA damage burdens may increase the reliance on PARP-dependent DNA repairs of cancer cells to render cell susceptibility to PARP inhibitor therapy. Here, we study if XRCC2 loss sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b4e05be643414aa80870519d0d93a4a
https://doi.org/10.21203/rs.3.rs-341240/v1
https://doi.org/10.21203/rs.3.rs-341240/v1
