Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kaiwu He"'
Autor:
Lulin Nie, Kaiwu He, Chaoming Qiu, Qing Li, Bocheng Xiong, Chuanyue Gao, Xiufen Zhang, Mei Jing, Wei Wu, Jianjun Liu, Gaoxiao Zhang, Zaijun Zhang, Xifei Yang, Yewei Sun, Yuqiang Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116415- (2024)
Tetramethylpyrazine nitrone (TBN), a novel derivative of tetramethylpyrazine (TMP) designed and synthesized by our group, possesses multi-functional mechanisms of action and displays broad protective effects in vitro and in animal models of age-relat
Externí odkaz:
https://doaj.org/article/9c28d0d3e49e4ca0ace1f7b19d2bea3f
Publikováno v:
Experimental Gerontology, Vol 187, Iss , Pp 112375- (2024)
Stress response is a fundamental mechanism for cell survival, providing protection under unfavorable conditions. Mitochondrial stress, in particular, can trigger mitophagy, a process that restores cellular health. Exhaustive exercise (EE) is a form o
Externí odkaz:
https://doaj.org/article/7b4bb9f19ba34cbb8c58507e56ddf758
Autor:
Kaiwu He, Lulin Nie, Tahir Ali, Zizhen Liu, Weifen Li, Ruyan Gao, Zena Zhang, Jianjun Liu, Zhongliang Dai, Yongmei Xie, Zaijun Zhang, Gongping Liu, Ming Dong, Zhi-Jian Yu, Shupeng Li, Xifei Yang
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background A wide spectrum of changes occurs in the brain with age, from molecular to morphological aspects, and inflammation accompanied by mitochondria dysfunction is one of the significant factors associated with age. Adiponectin (APN), a
Externí odkaz:
https://doaj.org/article/bef7bd9f1a1e4a68bb8431eaa56116a4
Autor:
Weifen Li, Tahir Ali, Chengyou Zheng, Zizhen Liu, Kaiwu He, Fawad Ali Shah, Qingguo Ren, Shafiq Ur Rahman, Ningning Li, Zhi-Jian Yu, Shupeng Li
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/d3944b2d9791412eaa27348b4b54b9e1
Autor:
Chao Huang, Erwei Gao, Feng Xiao, Qiongzhen Wu, Wei Liu, Yi Luo, Xiaohu Ren, Xiao Chen, Kaiwu He, Haiyan Huang, Qian Sun, Desheng Wu, Jianjun Liu
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
ObjectiveIndependent and interactive effects of multiple metals levels in urine on the risk of hyperuricemia (HUA) in the elderly were investigated.MethodsA total of 6,508 individuals from the baseline population of the Shenzhen aging-related disorde
Externí odkaz:
https://doaj.org/article/3fa87201e1574a13ad7db44ce178be81
Autor:
Weifen Li, Tahir Ali, Chengyou Zheng, Zizhen Liu, Kaiwu He, Fawad Ali Shah, Qingguo Ren, Shafiq Ur Rahman, Ningning Li, Zhi-Jian Yu, Shupeng Li
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract Background Selective serotonin reuptaker inhibitors, including fluoxetine, are widely studied and prescribed antidepressants, while their exact molecular and cellular mechanism are yet to be defined. We investigated the involvement of HDAC1
Externí odkaz:
https://doaj.org/article/7b8cb0bea14348edbd78c97149bceef9
Autor:
Wei Liu, Kaiwu He, Desheng Wu, Li Zhou, Guowei Li, Zequn Lin, Xifei Yang, Jianjun Liu, Maggie Pui Man Hoi
Publikováno v:
Molecules, Vol 27, Iss 4, p 1281 (2022)
Discovering new and effective drugs for the treatment of Alzheimer’s disease (AD) is a major clinical challenge. This study focuses on chemical modulation of the gut microbiome in an established murine AD model. We used the 16S rDNA sequencing tech
Externí odkaz:
https://doaj.org/article/4318451ca9f54737bd4a3aa334bc7e93
Autor:
Li Liu, Xian Wang, Li Zhou, Jing Yuan, Jianjun Liu, Weihong Chen, Lulin Nie, Zhiwei Guo, Yi Luo, Weimin Liu, Feiqi Zhu, Jiafei Zhang, Tian Li, Erwei Gao, Kaiwu He, Yidan Huang, Chunjie Yuan, Qingqing Zhu, Fang Ye, Xingchen Yu
Publikováno v:
BMJ Open, Vol 10, Iss 6 (2020)
Purpose The Shenzhen ageing-related disorder cohort was designed to detect the associations of lifestyle, environmental and genetic factors with major ageing-related disorders, especially neurological and mental disorders.Participants The cohort was
Externí odkaz:
https://doaj.org/article/2f9c5535763b4794bd434e13fc4dc2a1
Autor:
Tahir Ali, Qiang Hao, Najeeb Ullah, Shafiq Ur Rahman, Fawad Ali Shah, Kaiwu He, Chengyou Zheng, Weifen Li, Iram Murtaza, Yang Li, Yuhua Jiang, Zhen Tan, Shupeng Li
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Physical or psychological stress can cause an immunologic imbalance that disturbs the central nervous system followed by neuroinflammation. The association between inflammation and depression has been widely studied in recent years, though the molecu
Externí odkaz:
https://doaj.org/article/49b3ef1420eb4bfe93c36ed08bbf3666
Autor:
Shupeng Li, Kaiwu He, Fengzhu Xie, Li Zhou, Lulin Nie, Liangyu Zou, Xifei Yang, Shifeng Xiao, Jia Xu, Chen Yang, Kaiqin Zhang, Jianjun Liu
Publikováno v:
Aging (Albany NY)
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease threatening the health of the elderly, but the available therapeutic and preventive drugs remain suboptimal. Loganin, an iridoid glycoside extracted from Cornus offic