Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kaiwen Kam"'
Autor:
Xiaolu Sun, Carolina Thörn Pérez, Nagaraj Halemani D, Xuesi M Shao, Morgan Greenwood, Sarah Heath, Jack L Feldman, Kaiwen Kam
Publikováno v:
eLife, Vol 8 (2019)
How mammalian neural circuits generate rhythmic activity in motor behaviors, such as breathing, walking, and chewing, remains elusive. For breathing, rhythm generation is localized to a brainstem nucleus, the preBötzinger Complex (preBötC). Rhythmi
Externí odkaz:
https://doaj.org/article/6ab948b88984443998111fe9be1f2afd
Autor:
Maria Cristina D Picardo, Yae K Sugimura, Kaitlyn E Dorst, Prajkta S Kallurkar, Victoria T Akins, Xingru Ma, Ryoichi Teruyama, Romain Guinamard, Kaiwen Kam, Margaret S Saha, Christopher A Del Negro
Publikováno v:
PLoS Biology, Vol 17, Iss 2, p e2006094 (2019)
Inspiratory breathing movements depend on pre-Bötzinger complex (preBötC) interneurons that express calcium (Ca2+)-activated nonselective cationic current (ICAN) to generate robust neural bursts. Hypothesized to be rhythmogenic, reducing ICAN is pr
Externí odkaz:
https://doaj.org/article/13d356053e644b5cbe5889cb0fc164de
Publikováno v:
Journal of Neuroscience; 6/19/2024, Vol. 44 Issue 25, p1-13, 13p
Publikováno v:
Annual review of neuroscience, vol 45, iss 1
Annu Rev Neurosci
Annu Rev Neurosci
Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain and body. The apparent simplicity of breathing belies a complex neural control system, the breathing central pattern generator (bCPG), that exhibits diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbda510c9a6c1bb9d0c6d3478f3b034
https://doi.org/10.1146/annurev-neuro-090121-014424
https://doi.org/10.1146/annurev-neuro-090121-014424
Autor:
Sarah Heath, Kaiwen Kam, Jack L. Feldman, Carolina Thörn Pérez, Xiaolu Sun, Nagaraj Halemani D, Xuesi M. Shao, Morgan Greenwood
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
How mammalian neural circuits generate rhythmic activity in motor behaviors, such as breathing, walking, and chewing, remains elusive. For breathing, rhythm generation is localized to a brainstem nucleus, the preBötzinger Complex (preBötC). Rhythmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b36b05373a63283e4fb71cd571b0de5
https://escholarship.org/uc/item/5tw439hf
https://escholarship.org/uc/item/5tw439hf
Autor:
Lindsay A. Schwarz, Kevin Yackle, Liqun Luo, Jordan M. Sorokin, Jack L. Feldman, John R. Huguenard, Kaiwen Kam, Mark A. Krasnow
Publikováno v:
Science
Slow, controlled breathing has been used for centuries to promote mental calming, and it is used clinically to suppress excessive arousal such as panic attacks. However, the physiological and neural basis of the relationship between breathing and hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f8fbaa509d38746cf4a8e55aea6222
https://doi.org/10.1126/science.aai7984
https://doi.org/10.1126/science.aai7984
Autor:
Sarah Heath, Carolina Thörn Pérez, Morgan Greenwood, Xiaolu Sun, Jack L. Feldman, Nagaraj Halemani D, Xuesi M. Shao, Kaiwen Kam
SummaryHow mammalian neural circuits generate rhythmic activity in motor behaviors, such as breathing, walking, and chewing, remains elusive. For breathing, rhythm generation can be localized to a brainstem nucleus called the preBötzinger Complex (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af92b3860723455c21c5de808c1f6d0
https://doi.org/10.1101/665034
https://doi.org/10.1101/665034
Publikováno v:
Neuron. 91:602-614
Normal breathing in rodents requires activity of glutamatergic Dbx1-derived (Dbx1(+)) preBötzinger Complex (preBötC) neurons expressing somatostatin (SST). We combined in vivo optogenetic and pharmacological perturbations to elucidate the functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b878e19c95e4119084dc9b314d39cb
https://doi.org/10.1016/j.neuron.2016.07.003
https://doi.org/10.1016/j.neuron.2016.07.003
Autor:
Jack L. Feldman, Kaiwen Kam
Publikováno v:
Handbook of Brain Microcircuits
Breathing is a vital rhythmic motor behavior that mediates gas exchange to support metabolism and regulate pH. All mammals must breathe continuously and reliably from birth and modulate their breathing throughout life in response to changes in metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d658c4d5c5b78833b6152d1ff622330
https://doi.org/10.1093/med/9780190636111.003.0041
https://doi.org/10.1093/med/9780190636111.003.0041