Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Kaiwei Liang"'
Autor:
Jiaxing Jin, Hui Bai, Han Yan, Ting Deng, Tianyu Li, Ruijing Xiao, Lina Fan, Xue Bai, Hanhan Ning, Zhe Liu, Kai Zhang, Xudong Wu, Kaiwei Liang, Ping Ma, Xin Gao, Deqing Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The HIV-1 Tat protein hijacks the Super Elongation Complex (SEC) to stimulate viral transcription and replication. However, the mechanisms underlying Tat activation and inactivation, which mediate HIV-1 productive and latent infection, respe
Externí odkaz:
https://doaj.org/article/47ff490a35ef49b9882d927b501c3988
Autor:
Conghui Li, Zhinang Yin, Ruijing Xiao, Beili Huang, Yali Cui, Honghong Wang, Ying Xiang, Lingrui Wang, Lingyu Lei, Jiaqin Ye, Tianyu Li, Youquan Zhong, Fangteng Guo, Yuchen Xia, Pingping Fang, Kaiwei Liang
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-29 (2022)
Abstract Background G-quadruplexes (G4s) are unique noncanonical nucleic acid secondary structures, which have been proposed to physically interact with transcription factors and chromatin remodelers to regulate cell type-specific transcriptome and s
Externí odkaz:
https://doaj.org/article/a08a97cc3cab4532b53992f327221c55
Autor:
Xianchun Lan, Song Ding, Tianzhe Zhang, Ying Yi, Conghui Li, Wenwen Jin, Jian Chen, Kaiwei Liang, Hengbin Wang, Wei Jiang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Variant Polycomb complexes can have tissue-specific roles during development. Here they show that PCGF6 controls lineage-specification in human PSCs by promoting neuroectoderm differentiation and repressing mesendoderm differentiation via distinct do
Externí odkaz:
https://doaj.org/article/b85f428bd16441c99b86bb22d58ae234
Publikováno v:
Blood Science, Vol 1, Iss 1, Pp 50-56 (2019)
Abstract. Mixed lineage leukemia (MLL) is an aggressive and refractory blood cancer that predominantly occurs in pediatric patients and is often associated with poor prognosis and dismal outcomes. Thus far, no effective target therapy for the treatme
Externí odkaz:
https://doaj.org/article/29c5991416dc490badf905884470362b
Autor:
Christopher C. Ebmeier, Benjamin Erickson, Benjamin L. Allen, Mary A. Allen, Hyunmin Kim, Nova Fong, Jeremy R. Jacobsen, Kaiwei Liang, Ali Shilatifard, Robin D. Dowell, William M. Old, David L. Bentley, Dylan J. Taatjes
Publikováno v:
Cell Reports, Vol 20, Iss 5, Pp 1173-1186 (2017)
Summary: CDK7 phosphorylates the RNA polymerase II (pol II) C-terminal domain CTD and activates the P-TEFb-associated kinase CDK9, but its regulatory roles remain obscure. Here, using human CDK7 analog-sensitive (CDK7as) cells, we observed reduced ca
Externí odkaz:
https://doaj.org/article/388167747535488082fda9ce7d8b4cb5
Publikováno v:
Complexity, Vol 2018 (2018)
Timely detection and efficient recognition of fault are challenging for the bogie of high-speed train (HST), owing to the fact that different types of fault signals have similar characteristics in the same frequency range. Notice that convolutional n
Externí odkaz:
https://doaj.org/article/6aaa8bdbb2e34f0190e12fdde0ec08d0
Autor:
Baohua Xie, Zhinang Yin, Zhiye Hu, Junhui Lv, Chuanqian Du, Xiangping Deng, Yuan Huang, Qiuzi Li, Jian Huang, Kaiwei Liang, Hai-Bing Zhou, Chune Dong
Publikováno v:
Journal of Medicinal Chemistry. 66:6631-6651
Autor:
Chao Wu, Ting Xie, Ying Guo, Donghai Wang, Min Qiu, Ruyi Han, Guoliang Qing, Kaiwei Liang, Hudan Liu
Publikováno v:
Oncogene. 42:1321-1330
Autor:
Min Qiu, Zhinang Yin, Honghong Wang, Lingyu Lei, Conghui Li, Yali Cui, Rong Dai, Peiyuan Yang, Ying Xiang, Qiuzi Li, Junhui Lv, Zhuang Hu, Min Chen, Hai-Bing Zhou, Pingping Fang, Ruijing Xiao, Kaiwei Liang
Publikováno v:
Science Advances. 9
Cyclin-dependent kinase 12 (CDK12) interacts with cyclin K to form a functional nuclear kinase that promotes processive transcription elongation through phosphorylation of the C-terminal domain of RNA polymerase II (Pol II). To gain a comprehensive u
Publikováno v:
Energy & Fuels. 36:11278-11291