Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kaitong Liao"'
Autor:
Xiaobo Wang, Chengyuan Cai, Weiqi Lv, Kechen Chen, Jiaxin Li, Kaitong Liao, Yanqun Zhang, Hongxin Huang, Ying Lin, Zhili Rong, Xiaopin Duan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract CRISPR-based gene therapy offers precise targeting and specific editing of disease-related gene sequences, potentially yielding long-lasting treatment effects. However, efficient delivery remains a significant challenge for its widespread ap
Externí odkaz:
https://doaj.org/article/243debc11d674ee4890ae100ab1fb676
Autor:
Shufeng Ma, Kaitong Liao, Mengrao Li, Xinlong Wang, Jie Lv, Xin Zhang, Hongxin Huang, Lian Li, Tao Huang, Xiaohua Guo, Ying Lin, Zhili Rong
Publikováno v:
Nucleic Acids Research.
Liquid–liquid phase separation (LLPS) plays a critical role in regulating gene transcription via the formation of transcriptional condensates. However, LLPS has not been reported to be engineered as a tool to activate endogenous gene expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502157f12e862099c89a2c3c13e91d8d
https://doi.org/10.1093/nar/gkad301
https://doi.org/10.1093/nar/gkad301
Autor:
Shufeng Ma, Dong Wang, Jie Lv, Yongfei Hu, Ying Lin, Chengfang Liu, Xiaohua Guo, Kaitong Liao, Zhili Rong, Xinlong Wang
Publikováno v:
Nucleic Acids Research
The CRISPR/Cas system is widely used for genome editing. However, robust and targeted insertion of a DNA segment remains a challenge. Here, we present a fusion nuclease (Cas9-N57) to enhance site-specific DNA integration via a fused DNA binding domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c706257deeb94952f6864b553c629dcc
https://pubmed.ncbi.nlm.nih.gov/32986839
https://pubmed.ncbi.nlm.nih.gov/32986839