Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kaitlyn Wurz"'
Autor:
Joshua Z. Press, Kaitlyn Wurz, Barbara M. Norquist, Ming K. Lee, Christopher Pennil, Rochelle Garcia, Piri Welcsh, Barbara A. Goff, Elizabeth M. Swisher
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 12, Pp 993-1002 (2010)
Microinvasive carcinomas and high-grade intraepithelial neoplasms are commonly discovered within the fallopian tube of BRCA1 mutation carriers at the time of risk-reducing salpingo-oophorectomy, suggesting that many BRCA1-mutated ovarian carcinomas o
Externí odkaz:
https://doaj.org/article/2caf01596d57464698f1f626f1cd7481
Autor:
Toshiyasu Taniguchi, Emily Villegas, Jake Higgins, Kaitlyn Wurz, Simon P. Langdon, Fergus J. Couch, Kurapaty Venkatapoorna Chandramohan, Céline Jacquemont, Elizabeth M. Swisher, Wataru Sakai
Supplementary Figures S1-S5 from Functional Restoration of BRCA2 Protein by Secondary BRCA2 Mutations in BRCA2-Mutated Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647ab0fb9190e354ef3784ae983f9aa4
https://doi.org/10.1158/0008-5472.22378347.v1
https://doi.org/10.1158/0008-5472.22378347.v1
Autor:
Toshiyasu Taniguchi, Nicole Urban, Kaitlyn Wurz, Beth Y. Karlan, Wataru Sakai, Elizabeth M. Swisher
Supplementary Figure 1 and Table 1 from Secondary BRCA1 Mutations in BRCA1-Mutated Ovarian Carcinomas with Platinum Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326833dab57999c98ebe12c94fb1cd32
https://doi.org/10.1158/0008-5472.22375836.v1
https://doi.org/10.1158/0008-5472.22375836.v1
Autor:
Charles W. Drescher, Kavita Garg, Robert C Gentleman, Emily C. Knouf, Deepayan Sarkar, Yesenia Correa, Elizabeth M. Swisher, Rachael K. Parkin, Nicole Urban, Kathy O'Briant, Andrew K. Godwin, Kaitlyn Wurz, Walter L. Ruzzo, Jason D. Arroyo, Muneesh Tewari
Publikováno v:
Nucleic Acids Research
Although microRNAs (miRNAs) are important regulators of gene expression, the transcriptional regulation of miRNAs themselves is not well understood. We employed an integrative computational pipeline to dissect the transcription factors (TFs) responsi
Autor:
Barbara M. Norquist, Rochelle L. Garcia, Barbara A. Goff, Joshua Z. Press, Piri Welcsh, C. Pennil, Elizabeth M. Swisher, Kaitlyn Wurz, Ming K. Lee
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 12, Pp 993-1002 (2010)
Microinvasive carcinomas and high-grade intraepithelial neoplasms are commonly discovered within the fallopian tube of BRCA1 mutation carriers at the time of risk-reducing salpingo-oophorectomy, suggesting that many BRCA1-mutated ovarian carcinomas o
Autor:
Nicole Urban, Wataru Sakai, Kaitlyn Wurz, Toshiyasu Taniguchi, Beth Y. Karlan, Elizabeth M. Swisher
Publikováno v:
Cancer Research. 68:2581-2586
Although ovarian carcinomas with mutated BRCA1 or BRCA2 are sensitive to platinum compounds, such carcinomas eventually develop platinum resistance. Previously, we showed that acquired resistance to cisplatin in BRCA2-mutated tumors can be mediated b
Autor:
Toshiyasu Taniguchi, Elizabeth M. Swisher, Barbara M. Norquist, Wataru Sakai, Beth Y. Karlan, Rochelle L. Garcia, Kaitlyn Wurz, C. Pennil, Jenny Gross
Purpose Secondary somatic BRCA1/2 mutations may restore BRCA1/2 protein in hereditary ovarian carcinomas. In cell lines, BRCA2 restoration mediates resistance to platinum chemotherapy and poly (ADP-ribose) polymerase (PARP) inhibitors. We assessed pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22eb1b007487ebb7e60cabfaf41f7b2
https://europepmc.org/articles/PMC3157963/
https://europepmc.org/articles/PMC3157963/
Autor:
Kaitlyn Wurz, Barbara A. Goff, Elizabeth M. Swisher, Muneesh Tewari, Rochelle L. Garcia, Patrick S. Mitchell, Jun Haeng Lee
Publikováno v:
Genes, Chromosomes and Cancer.
MicroRNAs are often aberrantly expressed in human neoplasms and are postulated to play a role in neoplastic initiation and progression. miR-221 and miR-222 negatively regulate expression of CDKN1B (p27) and CDKN1C (p57), two cell cycle regulators exp
Autor:
Kimberly H. Allison, Vijaya Galic, Elizabeth M. Swisher, Julia Willner, Rochelle L. Garcia, Barbara A. Goff, Kaitlyn Wurz
Publikováno v:
Human pathology. 38(4)
Summary We evaluated alterations in p53, PIK3CA, PTEN, CTNNB1 ( β -catenin), MLH1, and BRAF among common histological subsets of epithelial ovarian tumors to characterize patterns of alterations of different molecular pathways. There were 12 clear c