Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kaitlyn N Burke"'
Autor:
Lorena C S Chaves, Nichole Orr-Burks, Daryll Vanover, Varun V Mosur, Sarah R Hosking, Pramod Kumar E K, Hyeyoon Jeong, Younghun Jung, José A F Assumpção, Hannah E Peck, Sarah L Nelson, Kaitlyn N Burke, McKinzie A Garrison, Robert A Arthur, Henry Claussen, Nicholas S Heaton, Eric R Lafontaine, Robert J Hogan, Chiara Zurla, Philip J Santangelo
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012345 (2024)
The CRISPR-Cas13 system has been proposed as an alternative treatment of viral infections. However, for this approach to be adopted as an antiviral, it must be optimized until levels of efficacy rival or exceed the performance of conventional approac
Externí odkaz:
https://doaj.org/article/ff2b71e5f2c14cc889ed30f7de84cd2e
Autor:
Heather M Froggatt, Kaitlyn N Burke, Ryan R Chaparian, Hector A Miranda, Xinyu Zhu, Benjamin S Chambers, Nicholas S Heaton
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009951 (2021)
Influenza A viruses encode their genomes across eight, negative sense RNA segments. The six largest segments produce mRNA transcripts that do not generally splice; however, the two smallest segments are actively spliced to produce the essential viral
Externí odkaz:
https://doaj.org/article/5f9db5129dae43e99d5e7c7d6e8b2e01
TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2.
Autor:
Joseph D Trimarco, Brook E Heaton, Ryan R Chaparian, Kaitlyn N Burke, Raquel A Binder, Gregory C Gray, Clare M Smith, Vineet D Menachery, Nicholas S Heaton
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009599 (2021)
Antiviral therapeutics are a front-line defense against virally induced diseases. Because viruses frequently mutate to escape direct inhibition of viral proteins, there is interest in targeting the host proteins that the virus must co-opt to complete
Externí odkaz:
https://doaj.org/article/485cd3cfaf524a5b9fa4517614d1a44a
Autor:
Tomer M. Yaron, Brook E. Heaton, Tyler M. Levy, Jared L. Johnson, Tristan X. Jordan, Benjamin M. Cohen, Alexander Kerelsky, Ting-Yu Lin, Katarina M. Liberatore, Danielle K. Bulaon, Samantha J. Van Nest, Nikos Koundouros, Edward R. Kastenhuber, Marisa N. Mercadante, Kripa Shobana-Ganesh, Long He, Robert E. Schwartz, Shuibing Chen, Harel Weinstein, Olivier Elemento, Elena Piskounova, Benjamin E. Nilsson-Payant, Gina Lee, Joseph D. Trimarco, Kaitlyn N. Burke, Cait E. Hamele, Ryan R. Chaparian, Alfred T. Harding, Aleksandra Tata, Xinyu Zhu, Purushothama Rao Tata, Clare M. Smith, Anthony P. Possemato, Sasha L. Tkachev, Peter V. Hornbeck, Sean A. Beausoleil, Shankara K. Anand, François Aguet, Gad Getz, Andrew D. Davidson, Kate Heesom, Maia Kavanagh-Williamson, David A. Matthews, Benjamin R. tenOever, Lewis C. Cantley, John Blenis, Nicholas S. Heaton
Publikováno v:
Science signaling, vol 15, iss 757
Multiple coronaviruses have emerged independently in the past 20 years that cause lethal human diseases. Although vaccine development targeting these viruses has been accelerated substantially, there remain patients requiring treatment who cannot be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f52febef82f67d02ed9c0d55e48f84
https://escholarship.org/uc/item/44d513nc
https://escholarship.org/uc/item/44d513nc
SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2
Autor:
Shankara Anand, Lewis C. Cantley, Long He, Joseph D. Trimarco, Benjamin E. Nilsson-Payant, Edward R. Kastenhuber, Harel Weinstein, Andrew D. Davidson, Maia Kavanagh-Williamson, Elena Piskounova, Anthony Possemato, Tyler Levy, Cait E. Hamele, Xinyu Zhu, Robert E. Schwartz, Benjamin R. tenOever, Kaitlyn N. Burke, John Blenis, Jared L. Johnson, Gina Lee, Kripa Shobana-Ganesh, François Aguet, Sasha Tkachev, Gad Getz, David A. Matthews, Clare M. Smith, Kate J. Heesom, Nicholas S. Heaton, Purushothama Rao Tata, Shuibing Chen, Danielle K. Bulaon, Aleksandra Tata, Ryan R. Chaparian, Peter Hornbeck, Alexander Kerelsky, Katarina M. Liberatore, Tomer M. Yaron, Brook E. Heaton, Marisa N. Mercadante, Benjamin M. Cohen, Alfred T. Harding, Olivier Elemento, Sean A. Beausoleil, Ting-Yu Lin, Tristan X. Jordan
Publikováno v:
bioRxiv
While vaccines are vital for preventing COVID-19 infections, it is critical to develop new therapies to treat patients who become infected. Pharmacological targeting of a host factor required for viral replication can suppress viral spread with a low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8def4c82dbd399ebda8cd6b0c2c056c
https://europepmc.org/articles/PMC7430567/
https://europepmc.org/articles/PMC7430567/
Autor:
Xinyu Zhu, Hector A. Miranda, Benjamin S. Chambers, Heather M. Froggatt, Ryan R. Chaparian, Nicholas S. Heaton, Kaitlyn N. Burke
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 9, p e1009951 (2021)
PLoS Pathogens, Vol 17, Iss 9, p e1009951 (2021)
Influenza A viruses encode their genomes across eight, negative sense RNA segments. The six largest segments produce mRNA transcripts that do not generally splice; however, the two smallest segments are actively spliced to produce the essential viral
Autor:
Chaves, Lorena C. S.1 (AUTHOR), Orr-Burks, Nichole2 (AUTHOR), Vanover, Daryll1 (AUTHOR), Mosur, Varun V.1 (AUTHOR), Hosking, Sarah R.2 (AUTHOR), Kumar E. K., Pramod1 (AUTHOR), Jeong, Hyeyoon1 (AUTHOR), Jung, Younghun1 (AUTHOR), Assumpção, José A. F.1 (AUTHOR), Peck, Hannah E.1 (AUTHOR), Nelson, Sarah L.3 (AUTHOR), Burke, Kaitlyn N.3 (AUTHOR), Garrison, McKinzie A.4 (AUTHOR), Arthur, Robert A.4 (AUTHOR), Claussen, Henry4 (AUTHOR), Heaton, Nicholas S.3,5 (AUTHOR), Lafontaine, Eric R.2 (AUTHOR), Hogan, Robert J.2 (AUTHOR), Zurla, Chiara1 (AUTHOR) chiara.zurla@emory.edu, Santangelo, Philip J.1 (AUTHOR) chiara.zurla@emory.edu
Publikováno v:
PLoS Pathogens. 7/5/2024, Vol. 20 Issue 7, p1-27. 27p.
Autor:
Luo, Zhaochen, Miranda, Hector A., Burke, Kaitlyn N., Spurrier, M. Ariel, Berry, Madison, Stover, Erica L., Spreng, Rachel L., Waitt, Greg, Soderblom, Erik J., Macintyre, Andrew N., Wiehe, Kevin, Heaton, Nicholas S.
Publikováno v:
Science Translational Medicine; 5/1/2024, Vol. 16 Issue 745, p1-15, 15p
Publikováno v:
Health & Medicine Week; 5/24/2024, p1569-1569, 1p
Autor:
Froggatt, Heather M.1 (AUTHOR), Burke, Kaitlyn N.1 (AUTHOR), Chaparian, Ryan R.1 (AUTHOR), Miranda, Hector A.1 (AUTHOR), Zhu, Xinyu1 (AUTHOR), Chambers, Benjamin S.1 (AUTHOR), Heaton, Nicholas S.1,2 (AUTHOR) nicholas.heaton@duke.edu
Publikováno v:
PLoS Pathogens. 9/27/2021, Vol. 17 Issue 9, p1-24. 24p.