Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kaitlyn M. Gayvert"'
Autor:
Kaitlyn M. Gayvert, Etienne Dardenne, Cynthia Cheung, Mary Regina Boland, Tal Lorberbaum, Jackline Wanjala, Yu Chen, Mark A. Rubin, Nicholas P. Tatonetti, David S. Rickman, Olivier Elemento
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2348-2356 (2016)
Mutations in transcription factor (TF) genes are frequently observed in tumors, often leading to aberrant transcriptional activity. Unfortunately, TFs are often considered undruggable due to the absence of targetable enzymatic activity. To address th
Externí odkaz:
https://doaj.org/article/8e9b8a2da68647c39b32d5b33c481580
Publikováno v:
Cancer Informatics, Vol 13s5 (2014)
Elucidating the molecular basis of human cancers is an extremely complex and challenging task. A wide variety of computational tools and experimental techniques have been used to address different aspects of this characterization. One major hurdle fa
Externí odkaz:
https://doaj.org/article/83b09c675d57493ca24fe982fafc3c35
Autor:
Matthew F Wipperman, Allen Z Lin, Kaitlyn M Gayvert, Benjamin Lahner, Selin Somersan-Karakaya, Xuefang Wu, Joseph Im, Minji Lee, Bharatkumar Koyani, Ian Setliff, Malika Thakur, Daoyu Duan, Aurora Breazna, Fang Wang, Wei Keat Lim, Gabor Halasz, Jacek Urbanek, Yamini Patel, Gurinder S Atwal, Jennifer D Hamilton, Samuel Stuart, Oren Levy, Andreja Avbersek, Rinol Alaj, Sara C Hamon, Olivier Harari
Publikováno v:
eLife, Vol 13 (2024)
Gait is impaired in musculoskeletal conditions, such as knee arthropathy. Gait analysis is used in clinical practice to inform diagnosis and monitor disease progression or intervention response. However, clinical gait analysis relies on subjective vi
Externí odkaz:
https://doaj.org/article/ad3bab55efd74d5882a3db592d2a1711
Autor:
Matthew F. Wipperman, Allen Z. Lin, Kaitlyn M. Gayvert, Benjamin Lahner, Selin Somersan-Karakaya, Xuefang Wu, Joseph Im, Minji Lee, Bharatkumar Koyani, Ian Setliff, Malika Thakur, Daoyu Duan, Aurora Breazna, Fang Wang, Wei Keat Lim, Gabor Halasz, Jacek Urbanek, Yamini Patel, Gurinder S. Atwal, Jennifer D. Hamilton, Clotilde Huyghues-Despointes, Oren Levy, Andreja Avbersek, Rinol Alaj, Sara C. Hamon, Olivier Harari
Biomechanical gait analysis informs clinical practice and research by linking characteristics of gait with neurological or musculoskeletal injury or disease. However, there are limitations to analyses conducted at gait labs as they require onerous co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62e554d0d68138655ca076315e09f685
https://doi.org/10.1101/2022.10.05.22280750
https://doi.org/10.1101/2022.10.05.22280750
Autor:
Kaitlyn M Gayvert, Omar Aly, James Platt, Marcus W Bosenberg, David F Stern, Olivier Elemento
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 1, p e1005308 (2017)
A promising alternative to address the problem of acquired drug resistance is to rely on combination therapies. Identification of the right combinations is often accomplished through trial and error, a labor and resource intensive process whose scale
Externí odkaz:
https://doaj.org/article/b51c1429d0444d8a8a38da999face423