Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kaitlyn M Eckert"'
Autor:
Maia Kinnebrew, Ellen J Iverson, Bhaven B Patel, Ganesh V Pusapati, Jennifer H Kong, Kristen A Johnson, Giovanni Luchetti, Kaitlyn M Eckert, Jeffrey G McDonald, Douglas F Covey, Christian Siebold, Arun Radhakrishnan, Rajat Rohatgi
Publikováno v:
eLife, Vol 8 (2019)
Previously we proposed that transmission of the hedgehog signal across the plasma membrane by Smoothened is triggered by its interaction with cholesterol (Luchetti et al., 2016). But how is cholesterol, an abundant lipid, regulated tightly enough to
Externí odkaz:
https://doaj.org/article/5a2e3cba37c9448299797b131d5c2018
Autor:
Gonçalo Vale, Sarah A. Martin, Matthew A. Mitsche, Bonne M. Thompson, Kaitlyn M. Eckert, Jeffrey G. McDonald
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 3, Pp 694-706 (2019)
An unbiased sample preparation free of interferents (i.e., competing analytes, detergents, plastics) is critical to any lipid MS workflow. Here we present a novel three-phase lipid extraction (3PLE) technique using a single-step liquid-liquid extract
Externí odkaz:
https://doaj.org/article/b39b26de91f041789b8729ddc8b9a4ad
Autor:
Kaitlyn M. Eckert, Jade Bowerman, Rupali Ugrankar, Hanaa Hariri, W. Mike Henne, Sanchari Datta, Gonçalo Vale, Jeffrey G. McDonald, Chase Corley
Publikováno v:
Proc Natl Acad Sci U S A
Fatty acids (FAs) are central cellular metabolites that contribute to lipid synthesis, and can be stored or harvested for metabolic energy. Dysregulation in FA processing and storage causes toxic FA accumulation or altered membrane compositions and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53abef5275d38ab7dd2804dde674968e
https://doi.org/10.1073/pnas.2011124117
https://doi.org/10.1073/pnas.2011124117
Publikováno v:
The Journal of investigative dermatology.
The skin acts as an endocrine organ capable of hormone production and response. Moreover, many skin conditions clinically improve with antiandrogen therapies. Despite their importance, we have an incomplete understanding of the composition of hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e0c887f3fb6d43ab17b89996e2fdc3
https://pubmed.ncbi.nlm.nih.gov/36208831
https://pubmed.ncbi.nlm.nih.gov/36208831
Autor:
Ritu Mishra, Kaitlyn M. Eckert, Carole R. Mendelson, Yaqin Yu, Lu Gao, Jeffrey G. McDonald, Jingfei Chen
Publikováno v:
The FASEB Journal. 34:16243-16261
Our previous research revealed that steroid receptor coactivators (Src)-1 and -2 serve a critical cooperative role in production of parturition signals, surfactant protein A and platelet-activating factor, by the developing mouse fetal lung (MFL). To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f71dd684cd73bde7aad0185d70b1d00
https://doi.org/10.1096/fj.202001809r
https://doi.org/10.1096/fj.202001809r
Autor:
Chukwuemeka George Anene-Nzelu, Michael Kinter, Hesham A. Sadek, Jainy J. Savla, Salim Abdisalaam, Luke I. Szweda, Abdallah Elnwasany, Roger Foo, Ursa Bezan Petric, Ana Helena Macedo Pereira, Ivan Menendez-Montes, Mohammed Kanchwala, Chalermchai Khemtong, Yuji Nakada, Wilson Lek Wen Tan, Shujuan Li, Craig R. Malloy, Mahmoud S. Ahmed, Kaitlyn M. Eckert, Ngoc Uyen Nhi Nguyen, A. Dean Sherry, Emily L Ensley, Aroumougame Asaithamby, Gaurav Sharma, Gonçalo Vale, Chao Xing, Linzhang Huang, Matthew A. Mitsche, Nicholas T. Lam, Philip W. Shaul, Alisson C. Cardoso, Joseph A. Hill, Waleed M. Elhelaly, Jeffrey G. McDonald
Publikováno v:
Nature Metabolism. 2:167-178
The neonatal mammalian heart is capable of regeneration for a brief window of time after birth. However, this regenerative capacity is lost within the first week of life, which coincides with a postnatal shift from anaerobic glycolysis to mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42c21436855a1b7e902d0de5305b7349
https://doi.org/10.1038/s42255-020-0169-x
https://doi.org/10.1038/s42255-020-0169-x
ImportanceSystemic sex steroid hormone aberrations often manifest in skin disease. The sebaceous, apocrine, and eccrine glands all play an important role in the response and production of these hormones in the skin. However, our ability to quantify h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::726c470dfcb94128d2de480ada5d99e7
https://doi.org/10.1101/2021.09.24.461688
https://doi.org/10.1101/2021.09.24.461688
Autor:
David B. Nelson, Ashlyn Lafferty, Chinmayee Venkatraman, Jeffrey G. McDonald, Kaitlyn M. Eckert, Donald D. McIntire, Catherine Y. Spong
Publikováno v:
JAMA Network Open. 5:e2237600
ImportancePreterm birth (PTB) is the leading cause of infant morbidity and mortality worldwide. It has been suggested that vaginal progesterone (VP) treatment may reduce the recurrence of PTB.ObjectiveTo evaluate the association of VP treatment with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef25983ca7797c1e68c2626f0f7f449a
https://doi.org/10.1001/jamanetworkopen.2022.37600
https://doi.org/10.1001/jamanetworkopen.2022.37600
Autor:
Tamia A. Harris-Tryon, Christos C. Zouboulis, Jeffrey G. McDonald, Gonçalo Vale, Courtney A. Prestwood, Mahendran Chinnappan, Kaitlyn M. Eckert, Chenlu Zhang, Marshall Edwards, Bonne M. Thompson, Methinee Artami
Publikováno v:
Proc Natl Acad Sci U S A
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by skin dryness, inflammation, and itch. A major hallmark of AD is an elevation of the immune cytokines IL-4 and IL-13. These cytokines lead to skin barrier disruption and li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b13b87818e4ff09cf6810926cdb15c
https://pubmed.ncbi.nlm.nih.gov/34521750
https://pubmed.ncbi.nlm.nih.gov/34521750
Autor:
Kristen A. Johnson, Rajat Rohatgi, Jeffrey G. McDonald, Ellen J. Iverson, Christian Siebold, Kaitlyn M. Eckert, Jennifer H. Kong, Maia Kinnebrew, Douglas F. Covey, Bhaven B. Patel, Giovanni Luchetti, Ganesh V. Pusapati, Arun Radhakrishnan
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1d45152dbf44b8f2d62dc7c387b2246
https://doi.org/10.1096/fasebj.2021.35.s1.05394
https://doi.org/10.1096/fasebj.2021.35.s1.05394