Výsledky vyhledávání - "Kaitlyn J. Andreano"

Data from The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor

Autor: Donald P. McDonnell, John D. Norris, Ching-yi Chang, Suzanne E. Wardell, Sarah Sammons, Myles Brown, Rinath Jeselsohn, Steffi Oesterreich, Sandeep Artham, Rachid Safi, Sunghee Park, Jennifer G. Baker, Kaitlyn J. Andreano

The estrogen receptor (ER/ESR1) is expressed in a majority of breast cancers and drugs that inhibit ER signaling are the cornerstone of breast cancer pharmacotherapy. Currently, aromatase inhibitors are the frontline endocrine interventions of choice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e02837e68b422e6bbee28a3fb031fa
https://doi.org/10.1158/1535-7163.c.6542740

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Supplementary Figures 1-13 and Supplementary Materials and Methods from The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor

Supplemental Figure 1: Structures of clinically relevant compounds used in this study. Supplemental Figure 2: Cells expressing both the ERWT and ERmuts have similar pharmacological responses to antiestrogens when compared to cells only expressing ERW

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b94a5c88ad45aa9476da6ffd8fc2fb
https://doi.org/10.1158/1535-7163.22520716

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The Dysregulated Pharmacology of Clinically Relevant

Autor: Kaitlyn J, Andreano, Jennifer G, Baker, Sunghee, Park, Rachid, Safi, Sandeep, Artham, Steffi, Oesterreich, Rinath, Jeselsohn, Myles, Brown, Sarah, Sammons, Suzanne E, Wardell, Ching-Yi, Chang, John D, Norris, Donald P, McDonnell

Publikováno v: Mol Cancer Ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3dcd24df0d921d40e429e0c8b3d6db7e
https://pubmed.ncbi.nlm.nih.gov/32381587

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