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Autor:
Wen-Yi Li, Kenneth Cusi, Joy Guingab, Reginald F. Frye, Srilaxmi Kalavalapalli, Jeremy P. Koelmel, Nishanth E. Sunny, Fernando Bril, Paige Andrews, Richard A. Yost, Timothy J. Garrett, Dhanya Jose, Kaitlyn I Abdo
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 315:E163-E173
Pioglitazone is effective in improving insulin resistance and liver histology in patients with nonalcoholic steatohepatitis (NASH). Because dysfunctional mitochondrial metabolism is a central feature of NASH, we hypothesized that an important target