Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kaitlyn D. Margison"'
Autor:
Conor O’Dwyer, Rebecca Yaworski, Sakie Katsumura, Peyman Ghorbani, Kaelan Gobeil Odai, Julia R.C. Nunes, Nicholas D. LeBlond, Sabrin Sanjana, Tyler T.K. Smith, Shauna Han, Kaitlyn D. Margison, Tommy Alain, Masahiro Morita, Morgan D. Fullerton
Publikováno v:
Hepatology Communications, Vol 4, Iss 6, Pp 876-889 (2020)
Choline is an essential nutrient and a critical component of the membrane phospholipid phosphatidylcholine (PC), the neurotransmitter acetylcholine, while also contributing to the methylation pathway. In the liver specifically, PC is the major membra
Externí odkaz:
https://doaj.org/article/6f21bd4cf0e644f38c1cf1dba71d17bc
Autor:
Meenakshi Sundaram, Kaitlin R. Curtis, Mohsen Amir Alipour, Nicholas D. LeBlond, Kaitlyn D. Margison, Rebecca A. Yaworski, Robin J. Parks, Adam D. McIntyre, Robert A. Hegele, Morgan D. Fullerton, Zemin Yao
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 11, Pp 2188-2196 (2017)
Recent cell culture and animal studies have suggested that expression of human apo C-III in the liver has a profound impact on the triacylglycerol (TAG)-rich VLDL1 production under lipid-rich conditions. The apoC-III Gln38Lys variant was identified i
Externí odkaz:
https://doaj.org/article/22d51921708541d59192f962d2353386
Autor:
Peyman Ghorbani, Sang Yong Kim, Tyler K.T. Smith, Lucía Minarrieta, Marisa K. Kilgour, Maja Ilijevska, Irina Alecu, Shayne A. Snider, Kaitlyn D. Margison, Julia R.C. Nunes, Daniel Woo, Ciara Pember, Conor O’Dwyer, Julie St-Pierre, Steffany A.L. Bennett, Meera G. Nair, Morgan D. Fullerton
Choline is an essential nutrient and in macrophages, mainly supports phosphatidylcholine (PC) synthesis. Cellular uptake and incorporation of choline into PC is critical for LPS-induced macrophage inflammation. Here, we examined choline metabolism in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0764d0bfb3645b653937339ae6a24fd
https://doi.org/10.1101/2022.09.30.510305
https://doi.org/10.1101/2022.09.30.510305
Publikováno v:
Chemical Reviews. 121:6699-6717
Bioorthogonal chemical reactions have emerged as convenient and rapid methods for incorporating unnatural functionality into living systems. Different prototype reactions have been optimized for use in biological settings. Optimization of 3 + 2 dipol
Autor:
Masahiro Morita, Morgan D. Fullerton, Kaelan Gobeil Odai, Nicholas D. LeBlond, Rebecca A. Yaworski, Sabrin Sanjana, Shauna Han, Conor O’Dwyer, Kaitlyn D. Margison, Tyler T.K. Smith, Tommy Alain, Peyman Ghorbani, Julia R. C. Nunes, Sakie Katsumura
Publikováno v:
Hepatology Communications, Vol 4, Iss 6, Pp 876-889 (2020)
Hepatology Communications
Hepatology Communications
Choline is an essential nutrient and a critical component of the membrane phospholipid phosphatidylcholine (PC), the neurotransmitter acetylcholine, while also contributing to the methylation pathway. In the liver specifically, PC is the major membra
Autor:
Miroslava Strmiskova, Allison R. Sherratt, Didier A. Bilodeau, John Paul Pezacki, Kaitlyn D. Margison, Noreen Ahmed
Publikováno v:
Chemical communications (Cambridge, England). 56(13)
Kinugasa reactions hold potential for bioorthogonal chemistry in that the reagents can be biocompatible. Unlike other bioorthogonal reaction products, β-lactams are potentially reactive, which can be useful for synthesizing new biomaterials. A limit
Publikováno v:
Chembiochem : a European journal of chemical biology. 21(7)
Trans-cyclooctenes (TCOs) represent interesting and highly reactive dipolarophiles for organic transformations including bioorthogonal chemistry. Herein we show that TCOs react rapidly with nitrones and that these reactions are bioorthogonal. Kinetic
Autor:
Shauna Han, Conor O’Dwyer, T. T. Smith, Peyman Ghorbani, K. Gobeil Odai, Kaitlyn D. Margison, Morgan D. Fullerton, Julia R. C. Nunes, Rebecca A. Yaworski, Nicholas D. LeBlond
Choline is an essential nutrient that is critical component of the membrane phospholipid phosphatidylcholine (PC), the neurotransmitter acetylcholine and the methylation pathway. In the liver specifically, PC is the major membrane constituent and can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5af0059389691edca4dd4b812228b4
Autor:
Hongbin Xu, Nicholas D. LeBlond, Kaitlyn D. Margison, Thao T. Nguyen, Conor O’Dwyer, Julia R. C. Nunes, Morgan D. Fullerton, Peyman Ghorbani, Shayne A. Snider, Steffany A. L. Bennett
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecd382a05e40f7b914e71b9fbca88e2
https://europepmc.org/articles/PMC6065184/
https://europepmc.org/articles/PMC6065184/
Autor:
Adam D. McIntyre, Robin J. Parks, Morgan D. Fullerton, Robert A. Hegele, Kaitlin R. Curtis, Meenakshi Sundaram, Zemin Yao, Kaitlyn D. Margison, Nicholas D. LeBlond, Rebecca A. Yaworski, Mohsen Amir Alipour
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 11, Pp 2188-2196 (2017)
Recent cell culture and animal studies have suggested that expression of human apo C-III in the liver has a profound impact on the triacylglycerol (TAG)-rich VLDL1 production under lipid-rich conditions. The apoC-III Gln38Lys variant was identified i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82501a71c9376f9183b15c50c071ee16
https://europepmc.org/articles/PMC5665666/
https://europepmc.org/articles/PMC5665666/