Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kaitlyn Braswell"'
Autor:
Daniel C. Lee, Sheeba Varghese-Gupta, Malathi Narayan, Chelsea Gibson, Umesh K. Jinwal, Kaitlyn Braswell, Juan Zhang, Ashley Zitnyar
Publikováno v:
Current Aging Science. 8:259-265
Leucine-Rich Repeat Kinase 2 (LRRK2) is a large, multi-domain protein that has been found to be mutated in patients with familial and sporadic Parkinson's disease, Alzheimer's disease and Crohn's disease. While the functions of LRRK2 are still largel
Publikováno v:
Experimental Neurology. 241:122-124
Autor:
Sheetal P. Dharia, John C. O'Leary, Kaitlyn Braswell, Umesh K. Jinwal, Chad A. Dickey, Juan Zhang, Jason E. Gestwicki, Tina Patel, Twisha Jani, Jose F. Abisambra
Publikováno v:
The Journal of biological chemistry, vol 287, iss 29
The RNA-binding protein, trans-active response DNA-binding protein 43 (TDP-43), is normally found in the nucleus, but in amyotrophic lateral sclerosis, frontal temporal dementia, and some cases of Alzheimer disease it is cleaved and mislocalized to t