Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kaitlyn A Barrow"'
Autor:
Elizabeth R. Vanderwall, Kaitlyn A. Barrow, Lucille M. Rich, David F. Read, Cole Trapnell, Oghenemega Okoloko, Steven F. Ziegler, Teal S. Hallstrand, Maria P. White, Jason S. Debley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Common alphacoronaviruses and human rhinoviruses (HRV) induce type I and III interferon (IFN) responses important to limiting viral replication in the airway epithelium. In contrast, highly pathogenic betacoronaviruses including SARS-CoV-2 m
Externí odkaz:
https://doaj.org/article/819ee770cae44309ba0d6e569bdb3358
Autor:
Oghenemega Okoloko, Elizabeth R. Vanderwall, Lucille M. Rich, Maria P. White, Stephen R. Reeves, Whitney E. Harrington, Kaitlyn A. Barrow, Jason S. Debley
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Rationale: SARS-CoV-2 gains entrance to airway epithelial cells (AECs) through binding of the viral spike protein to the angiotensin-converting enzyme 2 (ACE2) on the cell surface. However, ACE2 also converts angiotensin II into angiotensin-(1-7) and
Externí odkaz:
https://doaj.org/article/26e83c257499441486daeccf5e446cf8
Autor:
Stephen R. Reeves, Kaitlyn A. Barrow, Lucille M. Rich, Maria P. White, Nicholas J. Shubin, Christina K. Chan, Inkyung Kang, Steven F. Ziegler, Adrian M. Piliponsky, Thomas N. Wight, Jason S. Debley
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Human lung fibroblasts (HLFs) treated with the viral mimetic polyinosine-polycytidylic acid (poly I:C) form an extracellular matrix (ECM) enriched in hyaluronan (HA) that avidly binds monocytes and lymphocytes. Mast cells are important innate immune
Externí odkaz:
https://doaj.org/article/7c17dc8327b34d829110902b4e1ab511
Autor:
Stephen R. Reeves, Inkyung Kang, Christina K. Chan, Kaitlyn A. Barrow, Tessa K. Kolstad, Maria P. White, Steven F. Ziegler, Thomas N. Wight, Jason S. Debley
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Airway inflammation is a hallmark of asthma. Alterations in extracellular matrix (ECM) hyaluronan (HA) content have been shown to modulate the recruitment and retention of inflammatory cells. Bronchial epithelial cells (BECs) regu
Externí odkaz:
https://doaj.org/article/29e1999a836e4b409170229d612b058f
Autor:
Stephen R. Reeves, Kaitlyn A. Barrow, Maria P. White, Lucille M. Rich, Maryam Naushab, Jason S. Debley
Publikováno v:
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background An increasing number of studies using primary human bronchial epithelial cells (BECs) have reported intrinsic differences in the expression of several genes between cells from asthmatic and non-asthmatic donors. The stability of g
Externí odkaz:
https://doaj.org/article/46dfa1045843498eab89a507fc6ba815
Autor:
Tyler E. Billipp, Connie Fung, Lily M. Webeck, Derek B. Sargent, Matthew B. Gologorsky, Margaret M. McDaniel, Darshan N. Kasal, John W. McGinty, Kaitlyn A. Barrow, Lucille M. Rich, Alessio Barilli, Mark Sabat, Jason S. Debley, Richard Myers, Michael R. Howitt, Jakob von Moltke
Publikováno v:
bioRxiv
Tuft cells are solitary chemosensory epithelial cells that can sense lumenal stimuli at mucosal barriers and secrete effector molecules to regulate the physiology and immune state of their surrounding tissue. In the small intestine, tuft cells detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a5077dec2253525a95e08a19d5a318
https://doi.org/10.1101/2023.03.17.533208
https://doi.org/10.1101/2023.03.17.533208
Autor:
Ryan C. Murphy, Ying Lai, Matthew C. Altman, Kaitlyn A. Barrow, Kimberly A. Dill-McFarland, Matthew Liu, Jessica A. Hamerman, Adam Lacy-Hulbert, Adrian M. Piliponsky, Steven F. Ziegler, William A. Altemeier, Jason S. Debley, Sina A. Gharib, Teal S. Hallstrand
Publikováno v:
Journal of Allergy and Clinical Immunology.
Autor:
Kaitlyn A. Barrow, Lucille M. Rich, Elizabeth R. Vanderwall, Stephen R. Reeves, Jennifer A. Rathe, Maria P. White, Jason S. Debley
Publikováno v:
Methods and Protocols, Vol 4, Iss 1, p 7 (2021)
Given that the airway epithelium is the initial site of infection, study of primary human airway epithelial cells (AEC) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will be crucial to improved understanding of viral entr
Externí odkaz:
https://doaj.org/article/d5f093c03b924a1c9189249f612dc36e
Autor:
Kaitlyn A Barrow, Sarah Heidl, Elisabeth Brandstetter, Deborah A. Nickerson, Rachel E. Geyer, Sanjay Srivatsan, Eric Q. Konnick, Nahum Smith, Mark J. Rieder, Sriram Kosuri, Helen Y. Chu, Lea M. Starita, Misja Ilcisin, Shari Cho, L.M. Rich, Luis Gamboa, Denise J. McCulloch, Jay Shendure, Jeremy Stone, Jordan Opsahl, Ashley E. Kim, Caitlin R Wolf, Christina M. Lockwood, Peter D Han, Melissa Truong, Trevor Bedford, Wei Chen, Evan McDermot, Beth Martin, Sarah L Sohlberg, Brian Pfau, Jase Gehring, Katrina van Raay, Jason S Debley, Weizhi Zhong
Publikováno v:
Clinical Chemistry
Background The urgent need for massively scaled clinical testing for SARS-CoV-2, along with global shortages of critical reagents and supplies, has necessitated development of streamlined laboratory testing protocols. Conventional nucleic acid testin
Autor:
Steven F. Ziegler, Sina A. Gharib, Ryan C. Murphy, Jason S. Debley, Kaitlyn A Barrow, William A. Altemeier, Jessica A. Hamerman, Ying Lai, Adam Lacy-Hulbert, Adrian M. Piliponsky, Teal S. Hallstrand
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology