Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kaitlin M Dailey"'
Autor:
Kaitlin M Dailey, James M Small, Jessica E Pullan, Seth Winfree, Krysten E Vance, Megan Orr, Sanku Mallik, Kenneth W Bayles, Michael A Hollingsworth, Amanda E Brooks
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0289183 (2023)
Clostridium novyi has demonstrated selective efficacy against solid tumors largely due to the microenvironment contained within dense tumor cores. The core of a solid tumor is typically hypoxic, acidic, and necrotic-impeding the penetration of curren
Externí odkaz:
https://doaj.org/article/b537482f21ef4474b5d908f2d67ccbb3
Autor:
Kyle M. Pierce, William R. Miklavcic, Kyle P. Cook, Mikayla Sweitzer Hennen, Kenneth W. Bayles, Michael A. Hollingsworth, Amanda E. Brooks, Jessica E. Pullan, Kaitlin M. Dailey
Publikováno v:
Nanomaterials, Vol 11, Iss 11, p 3018 (2021)
While many classes of chemotherapeutic agents exist to treat solid tumors, few can generate a lasting response without substantial off-target toxicity despite significant scientific advancements and investments. In this review, the paths of developme
Externí odkaz:
https://doaj.org/article/c19bdbb1ecd94538b9ccb4e277118948
Autor:
William R. Miklavcic, Kyle M. Pierce, Jessica E. Pullan, Mikayla Sweitzer Hennen, Michael A. Hollingsworth, Kenneth W. Bayles, Kyle P. Cook, Kaitlin M. Dailey, Amanda E. Brooks
Publikováno v:
Nanomaterials, Vol 11, Iss 3018, p 3018 (2021)
Nanomaterials
Nanomaterials
While many classes of chemotherapeutic agents exist to treat solid tumors, few can generate a lasting response without substantial off-target toxicity despite significant scientific advancements and investments. In this review, the paths of developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06facf2cf964fdb9793167be9115d8d
https://www.mdpi.com/2079-4991/11/11/3018
https://www.mdpi.com/2079-4991/11/11/3018
Autor:
Amanda E. Brooks, Kambri Schaner, Benjamin D. Brooks, JuliAnne E Allgood, Paige R. Johnson, Kaitlin M. Dailey, Mackenzie A Ostlie
Publikováno v:
Future Microbiol
The development of a 'smart' drug capable of distinguishing tumor from host cells has been sought for centuries, but the microenvironment of solid tumors continues to confound therapeutics. Solid tumors present several challenges for current oncother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013a312dd97fab18dff128a2f2e11a72
https://pubmed.ncbi.nlm.nih.gov/33754804
https://pubmed.ncbi.nlm.nih.gov/33754804
Autor:
Kaitlin M. Dailey, Reed I. Jacobson, Paige R. Johnson, Taylor J. Woolery, Jiha Kim, Rick J. Jansen, Sanku Mallik, Amanda E. Brooks
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
The tumor microenvironment is characterized by anomalous vascularization, hypoxia, and acidity at the core of solid tumors that culminates in concentrated necrosis and immune system dysregulation among other effects. While this environment presents s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0358ecc673dca4ffb781d2a8f323b5d4
http://europepmc.org/articles/PMC8039391
http://europepmc.org/articles/PMC8039391
Autor:
Krysten Vance, Sanku Mallik, Michael A. Hollingsworth, Jandro Delgado, Amanda E. Brooks, Kenneth W. Bayles, Kaitlin M. Dailey, Reed I. Jacobson, Paige R. Johnson, Taylor M. Woolery, Megan Orr, Jiha Kim, Kyle McAndrews
Publikováno v:
Cancer Research. 81:PO-037
The efficacy of current oncotherapeutics is largely limited by an inability to access avascular tissues, which is in part responsible for forty years of stagnant pancreatic cancer statistics where the median survival remains a mere six months. Oncoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af4a4261959bf53bef1f6e3f84583495
https://doi.org/10.1158/1538-7445.panca21-po-037
https://doi.org/10.1158/1538-7445.panca21-po-037
Publikováno v:
International Journal of Molecular Sciences
Nanoparticles are becoming an increasingly popular tool for biomedical imaging and drug delivery. While the prevalence of nanoparticle drug-delivery systems reported in the literature increases yearly, relatively little translation from the bench to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87f4fdfddbdb90366440f01f5bdce9f
http://europepmc.org/articles/PMC6928924
http://europepmc.org/articles/PMC6928924
Autor:
Kaitlin M. Dailey, Eric M. Lewis, Andrew J. Scott, John C. Wilkinson, Shahzeb Khan, Amanda S. Wilkinson, Audrey M. Lenhausen
Publikováno v:
Biochemistry. 55(23)
Apoptosis inducing factor (AIF) plays a well-defined role in controlling cell death but is also a critical factor for maintaining mitochondrial energy homeostasis; how these dueling activities are balanced has remained largely elusive. To identify ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f013033707f6503fde6bb69bdc7874
https://pubmed.ncbi.nlm.nih.gov/27218139
https://pubmed.ncbi.nlm.nih.gov/27218139
Autor:
Jason M. Roe, Kevin Seely, Caleb J. Bussard, Emily Eischen Martin, Elizabeth G. Mouw, Kenneth W. Bayles, Michael A. Hollingsworth, Amanda E. Brooks, Kaitlin M. Dailey
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 2004 (2023)
Oncolytic bacteria are a classification of bacteria with a natural ability to specifically target solid tumors and, in the process, stimulate a potent immune response. Currently, these include species of Klebsiella, Listeria, Mycobacteria, Streptococ
Externí odkaz:
https://doaj.org/article/cbabaab1fee549e4bb6e1a4925d48eec