Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kaitlin J. Basham"'
Autor:
Hammer, Morgan K. Penny, Antonio M. Lerario, Kaitlin J. Basham, Sahiti Chukkapalli, Dipika R. Mohan, Chris LaPensee, Kimber Converso-Baran, Mark J. Hoenerhoff, Laura Suárez-Fernández, Carmen González del Rey, Thomas J. Giordano, Ruolan Han, Erika A. Newman, Gary D.
Publikováno v:
Cancers; Volume 15; Issue 14; Pages: 3559
Adrenocortical carcinoma (ACC) is a rare but highly aggressive cancer with limited treatment options and poor survival for patients with advanced disease. An improved understanding of the transcriptional programs engaged in ACC will help direct ratio
Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner
Autor:
Kate M. Warde, Lorenzo J. Smith, Lihua Liu, Chris J. Stubben, Brian K. Lohman, Parker W. Willett, Julia L. Ammer, Guadalupe Castaneda-Hernandez, Sikiru O. Imodoye, Chenge Zhang, Kara D. Jones, Kimber Converso-Baran, H. Atakan Ekiz, Marc Barry, Michael R. Clay, Katja Kiseljak-Vassiliades, Thomas J. Giordano, Gary D. Hammer, Kaitlin J. Basham
Publikováno v:
Nature Aging.
Autor:
Andrew W Hahn, Bilal A Siddiqui, Javier Leo, Eleonora Dondossola, Kaitlin J Basham, Cindy K Miranti, Daniel E Frigo
Publikováno v:
Endocrinology.
Given the central role of the androgen receptor (AR) in prostate cancer cell biology, AR-targeted therapies have been the backbone of prostate cancer treatment for over 50 years. New data indicate that AR is expressed in additional cell types within
Autor:
Javier Leo, Eleonora Dondossola, Kaitlin J Basham, Nathaniel R Wilson, Omar Alhalabi, Jianjun Gao, Katherine C Kurnit, Michael G White, Jennifer L McQuade, Shannon N Westin, Elizabeth A Wellberg, Daniel E Frigo
Publikováno v:
Endocrinology.
The androgen receptor (AR) is one of the oldest therapeutic targets in oncology and continues to dominate the treatment landscape for advanced prostate cancer, where nearly all treatment regimens include some form of AR modulation. In this regard, AR
Autor:
Morgan K. Penny, Antonio M. Lerario, Kaitlin J. Basham, Sahiti Chukkapalli, Yingjie Yu, Dipika R. Mohan, Chris LaPensee, Kimber Converso-Baran, Mark J. Hoenerhoff, Laura Suárez Fernández, Carmen González del Rey, Thomas J. Giordano, Ruolan Han, Erika A. Newman, Gary D. Hammer
Adrenocortical carcinoma (ACC) is a rare, but highly aggressive cancer with limited treatment options and poor survival for patients with advanced disease. Improved understanding of transcriptional programs engaged in ACC will help direct rational, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d95cd3c2930684251b005d5191e716
https://doi.org/10.1101/2022.10.23.509323
https://doi.org/10.1101/2022.10.23.509323
Senescence-Induced Immune Remodeling Facilitates Metastatic Adrenal Cancer in a Sex-Dimorphic Manner
Autor:
Kate M. Warde, Lihua Liu, Lorenzo J. Smith, Brian K. Lohman, Chris J. Stubben, H. Atakan Ekiz, Julia L. Ammer, Kimber Converso-Baran, Thomas J. Giordano, Gary D. Hammer, Kaitlin J. Basham
Aging is a carcinogen that markedly increases cancer risk, yet we have limited mechanistic understanding of cancer initiation in aged cells. Here, we demonstrate induction of the hallmark aging process cellular senescence, triggered by loss of Wnt in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5cfadeccc109b321b91df3229686702
https://doi.org/10.1101/2022.04.29.488426
https://doi.org/10.1101/2022.04.29.488426
Autor:
Christopher R. LaPensee, Amy E. O’Connell, Donald W. Little, Kleiton S Borges, Gary D. Hammer, David T. Breault, Kaitlin J. Basham
Publikováno v:
Journal of the Endocrine Society
Dysregulation of normal adrenal structure and function contributes to a spectrum of diseases from hypoplasia to cancer. Peripheral adrenocortical progenitor cells in the zona glomerulosa (zG) centripetally migrate and differentiate to replenish stero
Autor:
Gary D. Hammer, Kaitlin J. Basham
Publikováno v:
Mol Cell Endocrinol
The adrenal cortex functions to produce steroid hormones necessary for life. To maintain its functional capacity throughout life, the adrenal cortex must be continually replenished and rapidly repaired following injury. Moreover, the adrenal responds
Publikováno v:
Journal of the Endocrine Society
Dysregulation of normal adrenal structure and function contributes to a spectrum of diseases from hypoplasia to cancer. Peripheral adrenocortical progenitor cells in the zona glomerulosa (zG) centripetally migrate and differentiate to replenish stero
Autor:
J. WilmouthJr, J. Olabe, Florence Roucher-Boulez, Antoine Martinez, Kaitlin J. Basham, Gary D. Hammer, Pierre Val, C. Lucas
Publikováno v:
Annales d'Endocrinologie. 81:178-179
Objectif Le corticosurrenalome (CCS) est un cancer rare et agressif se developpant a partir des cellules steroidogenes du cortex surrenalien. L’inactivation de l’E3 ubiquitine ligase Zinc and Ring Finger 3 (ZNRF3), un suppresseur de tumeur putati