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pro vyhledávání: '"Kaitlin Huffman"'
Autor:
Kaitlin Huffman, Jack Ballantyne
Publikováno v:
iScience, Vol 26, Iss 11, Pp 107961- (2023)
Summary: Standard methods of mixture analysis involve subjecting a dried crime scene sample to a “bulk” DNA extraction method such that the resulting isolate compromises a homogenized DNA mixture from the individual donors. If, however, instead o
Externí odkaz:
https://doaj.org/article/beb628503d2448c2851034d6bce7c06b
Publikováno v:
Journal of Forensic Sciences. 68:275-288
Since Y-STR typing only amplifies male Y chromosomal DNA, it can simplify the interpretation of some DNA mixtures that contain female DNA. However, if there are multiple male contributors, mixed Y-STR DNA profiles will often be obtained. Y-STR mixtur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e922b810104bab351b7331a2702a8587
https://doi.org/10.1111/1556-4029.15150
https://doi.org/10.1111/1556-4029.15150
Autor:
Kaitlin Huffman, Jack Ballantyne
Publikováno v:
Genes; Volume 13; Issue 9; Pages: 1658
Analysis of complex DNA mixtures comprised of related individuals requires a great degree of care due to the increased risk of falsely including non-donor first-degree relatives. Although alternative likelihood ratio (LR) propositions that may aid in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c5e6f93c33fd582c0bceb9320f2149
Publikováno v:
Genes; Volume 13; Issue 7; Pages: 1117
When a minor DNA component to a binary mixture is present at a weight ratio of approximately 1:50 or less, the presence of this minor donor is undetectable (or barely detectable) by standard mixture deconvolution approaches. In an attempt to retrieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f17a5938d0453620ea19bb047657320
Autor:
Kaitlin Huffman, Jack Ballantyne
Publikováno v:
Genes; Volume 14; Issue 3; Pages: 674
Probabilistic genotyping (PG) and its associated software has greatly aided in forensic DNA mixture analysis, with it primarily being applied to mixed DNA profiles obtained from bulk cellular extracts. However, these software applications do not alwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9622ca0a342bd5059086666546c7e61e
https://doi.org/10.3390/genes14030674
https://doi.org/10.3390/genes14030674
Publikováno v:
Sciencejustice : journal of the Forensic Science Society. 62(2)
DNA mixtures are a common source of crime scene evidence and are often one of the more difficult sources of biological evidence to interpret. With the implementation of probabilistic genotyping (PG), mixture analysis has been revolutionized allowing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef21757a53371a2056291b09949d73b
https://pubmed.ncbi.nlm.nih.gov/35277229
https://pubmed.ncbi.nlm.nih.gov/35277229
Publikováno v:
Sciencejustice : journal of the Forensic Science Society. 61(1)
Deconvolution of forensic DNA mixtures into their individual component DNA (geno)types is of great investigative value, though often complex and difficult. Two-person mixtures comprising a major and minor contributor are often easily interpreted alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99dd46f49a6c18ddc947b57a78630bbc
https://pubmed.ncbi.nlm.nih.gov/33357824
https://pubmed.ncbi.nlm.nih.gov/33357824