Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Kaitlin H, Wade"'
Autor:
Naveed Sattar, Kaitlin H Wade, Dimitri J Pournaras, Nicholas J Timpson, Madeleine L Smith, Lucy J Goudswaard, Laura J Corbin
Publikováno v:
BMJ Medicine, Vol 3, Iss 1 (2024)
Associations between obesity and health are unequivocal and coupled with a substantial body of evidence suggesting that associations are likely causal. These associations and the supporting causal evidence are useful, but hide both the inadequacies o
Externí odkaz:
https://doaj.org/article/545b6bc4f080412296f2f3e270f12e00
Autor:
Jonathan P. Bradfeld, Rachel L. Kember, Anna Ulrich, Zhanna Balkhiyarova, Akram Alyass, Izzuddin M. Aris, Joshua A. Bell, K. Alaine Broadaway, Zhanghua Chen, Jin-Fang Chai, Neil M. Davies, Dietmar Fernandez-Orth, Mariona Bustamante, Ruby Fore, Amitavo Ganguli, Anni Heiskala, Jouke-Jan Hottenga, Carmen Íñiguez, Sayuko Kobes, Jaakko Leinonen, Estelle Lowry, Leo-Pekka Lyytikainen, Anubha Mahajan, Niina Pitkänen, Theresia M. Schnurr, Christian Theil Have, David P. Strachan, Elisabeth Thiering, Suzanne Vogelezang, Kaitlin H. Wade, Carol A. Wang, Andrew Wong, Louise Aas Holm, Alessandra Chesi, Catherine Choong, Miguel Cruz, Paul Elliott, Steve Franks, Christine Frithiof-Bøjsøe, W. James Gauderman, Joseph T. Glessner, Vicente Gilsanz, Kendra Griesman, Robert L. Hanson, Marika Kaakinen, Heidi Kalkwarf, Andrea Kelly, Joseph Kindler, Mika Kähönen, Carla Lanca, Joan Lappe, Nanette R. Lee, Shana McCormack, Frank D. Mentch, Jonathan A. Mitchell, Nina Mononen, Harri Niinikoski, Emily Oken, Katja Pahkala, Xueling Sim, Yik-Ying Teo, Leslie J. Baier, Toos van Beijsterveldt, Linda S. Adair, Dorret I. Boomsma, Eco de Geus, Mònica Guxens, Johan G. Eriksson, Janine F. Felix, Frank D. Gilliland, Penn Medicine Biobank, Torben Hansen, Rebecca Hardy, Marie-France Hivert, Jens-Christian Holm, Vincent W. V. Jaddoe, Marjo-Riitta Järvelin, Terho Lehtimäki, David A. Mackey, David Meyre, Karen L. Mohlke, Juha Mykkänen, Sharon Oberfeld, Craig E. Pennell, John R. B. Perry, Olli Raitakari, Fernando Rivadeneira, Seang-Mei Saw, Sylvain Sebert, John A. Shepherd, Marie Standl, Thorkild I. A. Sørensen, Nicholas J. Timpson, Maties Torrent, Gonneke Willemsen, Elina Hypponen, Chris Power, The Early Growth Genetics Consortium, Mark I. McCarthy, Rachel M. Freathy, Elisabeth Widén, Hakon Hakonarson, Inga Prokopenko, Benjamin F. Voight, Babette S. Zemel, Struan F. A. Grant, Diana L. Cousminer
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/e9448135c0a94a80bb3b73a022f181ed
Autor:
Jonathan P. Bradfield, Rachel L. Kember, Anna Ulrich, Zhanna Balkhiyarova, Akram Alyass, Izzuddin M. Aris, Joshua A. Bell, K. Alaine Broadaway, Zhanghua Chen, Jin-Fang Chai, Neil M. Davies, Dietmar Fernandez-Orth, Mariona Bustamante, Ruby Fore, Amitavo Ganguli, Anni Heiskala, Jouke-Jan Hottenga, Carmen Íñiguez, Sayuko Kobes, Jaakko Leinonen, Estelle Lowry, Leo-Pekka Lyytikainen, Anubha Mahajan, Niina Pitkänen, Theresia M. Schnurr, Christian Theil Have, David P. Strachan, Elisabeth Thiering, Suzanne Vogelezang, Kaitlin H. Wade, Carol A. Wang, Andrew Wong, Louise Aas Holm, Alessandra Chesi, Catherine Choong, Miguel Cruz, Paul Elliott, Steve Franks, Christine Frithioff-Bøjsøe, W. James Gauderman, Joseph T. Glessner, Vicente Gilsanz, Kendra Griesman, Robert L. Hanson, Marika Kaakinen, Heidi Kalkwarf, Andrea Kelly, Joseph Kindler, Mika Kähönen, Carla Lanca, Joan Lappe, Nanette R. Lee, Shana McCormack, Frank D. Mentch, Jonathan A. Mitchell, Nina Mononen, Harri Niinikoski, Emily Oken, Katja Pahkala, Xueling Sim, Yik-Ying Teo, Leslie J. Baier, Toos van Beijsterveldt, Linda S. Adair, Dorret I. Boomsma, Eco de Geus, Mònica Guxens, Johan G. Eriksson, Janine F. Felix, Frank D. Gilliland, Penn Medicine Biobank, Torben Hansen, Rebecca Hardy, Marie-France Hivert, Jens-Christian Holm, Vincent W. V. Jaddoe, Marjo-Riitta Järvelin, Terho Lehtimäki, David A. Mackey, David Meyre, Karen L. Mohlke, Juha Mykkänen, Sharon Oberfield, Craig E. Pennell, John R. B. Perry, Olli Raitakari, Fernando Rivadeneira, Seang-Mei Saw, Sylvain Sebert, John A. Shepherd, Marie Standl, Thorkild I. A. Sørensen, Nicholas J. Timpson, Maties Torrent, Gonneke Willemsen, Elina Hypponen, Chris Power, The Early Growth Genetics Consortium, Mark I. McCarthy, Rachel M. Freathy, Elisabeth Widén, Hakon Hakonarson, Inga Prokopenko, Benjamin F. Voight, Babette S. Zemel, Struan F. A. Grant, Diana L. Cousminer
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Pubertal growth patterns correlate with future health outcomes. However, the genetic mechanisms mediating growth trajectories remain largely unknown. Here, we modeled longitudinal height growth with Super-Imposition by Translation
Externí odkaz:
https://doaj.org/article/01f378c433c944aea3f99eb2232d6404
Autor:
Charlie Hatcher, George Richenberg, Samuel Waterson, Long H. Nguyen, Amit D. Joshi, Robert Carreras-Torres, Victor Moreno, Andrew T. Chan, Marc Gunter, Yi Lin, Conghui Qu, Mingyang Song, Graham Casey, Jane C. Figueiredo, Stephen B. Gruber, Jochen Hampe, Heather Hampel, Mark A. Jenkins, Temitope O. Keku, Ulrike Peters, Catherine M. Tangen, Anna H. Wu, David A. Hughes, Malte C. Rühlemann, Jeroen Raes, Nicholas J. Timpson, Kaitlin H. Wade
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The role of the human gut microbiome in colorectal cancer (CRC) is unclear as most studies on the topic are unable to discern correlation from causation. We apply two-sample Mendelian randomization (MR) to estimate the causal relationship be
Externí odkaz:
https://doaj.org/article/3de8785a834d4867853ad4bb6d8b5078
Autor:
Charlie Hatcher, George Richenberg, Samuel Waterson, Long H. Nguyen, Amit D. Joshi, Robert Carreras-Torres, Victor Moreno, Andrew T. Chan, Marc Gunter, Yi Lin, Conghui Qu, Mingyang Song, Graham Casey, Jane C. Figueiredo, Stephen B. Gruber, Jochen Hampe, Heather Hampel, Mark A. Jenkins, Temitope O. Keku, Ulrike Peters, Catherine M. Tangen, Anna H. Wu, David A. Hughes, Malte C. Rühlemann, Jeroen Raes, Nicholas J. Timpson, Kaitlin H. Wade
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/e6455a7ead5b4970bd2995d680b3ff26
Autor:
Kaitlin H Wade, Si Fang, Nicholas J Timpson, Laura J Corbin, Nancy McBride, Thomas Battram, Matthew A Lee, Charlie Hatcher, Wenxin Wan, Luke A McGuinness
Publikováno v:
Wellcome Open Research, Vol 7 (2023)
Mendelian randomization (MR) is increasingly used for generating estimates of the causal impact of exposures on outcomes. Evidence suggests a causal role of excess adipose tissue (adiposity) on many health outcomes. However, this body of work has not
Externí odkaz:
https://doaj.org/article/00574839a43c4f4087f8c36434469457
Autor:
Sebastian May-Wilson, Nana Matoba, Kaitlin H. Wade, Jouke-Jan Hottenga, Maria Pina Concas, Massimo Mangino, Eryk J. Grzeszkowiak, Cristina Menni, Paolo Gasparini, Nicholas J. Timpson, Maria G. Veldhuizen, Eco de Geus, James F. Wilson, Nicola Pirastu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Genetic determinants of food consumption and food liking are likely to be distinct, although it has not been well studied. Here, the authors identify genetic variants associated with food-liking, finding that different food-liking traits correlate wi
Externí odkaz:
https://doaj.org/article/a01d04ec4bf9466094344055139614d6
Autor:
Maxime M. Bos, Neil J. Goulding, Matthew A. Lee, Amy Hofman, Mariska Bot, René Pool, Lisanne S. Vijfhuizen, Xiang Zhang, Chihua Li, Rima Mustafa, Matt J. Neville, Ruifang Li-Gao, Stella Trompet, Marian Beekman, Nienke R. Biermasz, Dorret I. Boomsma, Irene de Boer, Constantinos Christodoulides, Abbas Dehghan, Ko Willems van Dijk, Ian Ford, Mohsen Ghanbari, Bastiaan T. Heijmans, M. Arfan Ikram, J. Wouter Jukema, Dennis O. Mook-Kanamori, Fredrik Karpe, Annemarie I. Luik, L. H. Lumey, Arn M. J. M. van den Maagdenberg, Simon P. Mooijaart, Renée de Mutsert, Brenda W. J. H. Penninx, Patrick C. N. Rensen, Rebecca C. Richmond, Frits R. Rosendaal, Naveed Sattar, Robert A. Schoevers, P. Eline Slagboom, Gisela M. Terwindt, Carisha S. Thesing, Kaitlin H. Wade, Carolien A. Wijsman, Gonneke Willemsen, Aeilko H. Zwinderman, Diana van Heemst, Raymond Noordam, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background Sleep traits are associated with cardiometabolic disease risk, with evidence from Mendelian randomization (MR) suggesting that insomnia symptoms and shorter sleep duration increase coronary artery disease risk. We combined adjuste
Externí odkaz:
https://doaj.org/article/3a4e89b02a4e4bc9b561d382d0215d2b
Autor:
Amanda Hughes, Kaitlin H. Wade, Matt Dickson, Frances Rice, Alisha Davies, Neil M. Davies, Laura D. Howe
Publikováno v:
npj Science of Learning, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Good health is positively related to children’s educational outcomes, but relationships may not be causal. Demonstrating a causal influence would strongly support childhood and adolescent health as important for education policy. We applie
Externí odkaz:
https://doaj.org/article/9ef7eb6c76a340338ae4503449321759
Autor:
Joshua A Bell, Kaitlin H Wade, Linda M O'Keeffe, David Carslake, Emma E Vincent, Michael V Holmes, Nicholas J Timpson, George Davey Smith
Publikováno v:
PLoS Medicine, Vol 18, Iss 9, p e1003751 (2021)
BackgroundThe potential benefits of gaining body muscle for cardiovascular disease (CVD) susceptibility, and how these compare with the potential harms of gaining body fat, are unknown. We compared associations of early life changes in body lean mass
Externí odkaz:
https://doaj.org/article/b6e992ead62a408f97e933688a6be405