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Complementary target engagement and functional assays to probe NLRP3 inflammasome pathway antagonism
Autor:
Martha A. O’Brien, Matt Robers, Kelly Teske, Cesear Corona, Jim Vasta, Jennifer Wilkinson, Ngan Lam, Kaitlin Dunn Hoffman, James Cali, Dan Lazar
Publikováno v:
The Journal of Immunology. 208:52.12-52.12
Inflammasomes are critical to the innate immune system and implicated in numerous chronic and acute inflammatory diseases. Having tools to screen inflammasome modulatory drugs is critical, especially for the NLRP3 inflammasome that is triggered by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74743a1481af8a795e251422332224e9
https://doi.org/10.4049/jimmunol.208.supp.52.12
https://doi.org/10.4049/jimmunol.208.supp.52.12
