Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy

Autor: Aarif O. Eifan, Mohamed H. Shamji, Alkis Togias, Guy W. Scadding, Tielin Qin, Peter Adler Würtzen, Michelle L. Sever, Janice A. Layhadi, Srinath Sanda, Gerald T. Nepom, Stephen R. Durham, Kristina M. Harris, Ellen Macfarlane, David W. Larson, Kaitie Lawson, Rebecca Parkin

Publikováno v: The Journal of allergy and clinical immunology. 148(4)

Introduction There is no detailed comparison of allergen-specific immunoglobulin responses following sublingual immunotherapy (SLIT) and subcutaneous immunotherapy (SCIT). Objective We sought to compare nasal and systemic timothy grass pollen (TGP)-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7ba878214193559f5390380a28c8d6
https://pubmed.ncbi.nlm.nih.gov/33819508

Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity

Autor: Asha Sudra, Olympia Tsilochristou, Graham Roberts, Eduard Chani, Kathryn Hersee, Claire Duncan, Rianne Wester, Charlotte Stedman, Gideon Lack, Jenna Heath, Natalia do Couto Francisco, Joy Laurienzo Panza, Tiffany Miller, Victoria Offord, Michelle L. Sever, Louise Coverdale, Susan Chan, Audrey Plough, Amy Nixon, Adam T. Fox, Alastair Wilson, Alicia Parr, Kerry Richards, Una O'Dwyer-Leeson, Gail Harland, Adam Asare, Kaitie Lawson, George Du Toit, Natalie Witham, Monica Basting, Judith Evind, Jack W. Hu, Catherine Clarke, Alick Stephens, Helen R. Fisher, Peter H. Sayre, Mable Abraham, Marshall Plaut, Margarita Gomez Lorenzo, Matthew Crossley, Muhsinah Adam, Ewa Pietraszewicz, Devi Patkunam, Aine Sheridan, Gemma Deutsch, Natalia Bécares, Kathryn Cockerell, Stephanie Lussier, Celine Wu, Henry T. Bahnson, Fiona Watson, Noha Lim, Don Whitehouse, Travis Mason, Suzana Radulovic, Richard Cleaver

Publikováno v: Tsilochristou, O, du Toit, G, Sayre, P H, Roberts, G, Lawson, K, Sever, M L, Bahnson, H T, Radulovic, S, Basting, M, Plaut, M, Lack, G, Chan, S, Fox, A, Fisher, H, Abraham, M, Adam, M, Coverdale, L, Duncan, C, Nixon, A, O'Dwyer-Leeson, U, Offord, V, Sheridan, A, Watson, F, Witham, N, Cockerell, K, Harland, G, Miller, T, Stedman, C, Clarke, C, Cleaver, R, Deutsch, G, Parr, A, Becares, N, Crossley, M, Francisco, N D C, Richards, K, Pietraszewicz, E, Stephens, A, Sudra, A, Wester, R, Wilson, A, Wu, C, Heath, J, Hersee, K, Patkunam, D, Asare, A, Chani, E, Evind, J & Lim, N & Plough, A 2019, ' Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity ', Journal of Allergy and Clinical Immunology, vol. 144, no. 2, pp. 494-503 . https://doi.org/10.1016/j.jaci.2019.04.025

BACKGROUND: Staphylococcus aureus has been implicated in the pathophysiology of eczema, allergic rhinitis, asthma, and food allergy. S aureus is a marker of more severe eczema, which is a risk factor for food sensitization/allergy. Therefore it might

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc600af8fc1be6e026908608bbf2203
https://kclpure.kcl.ac.uk/en/publications/69e24470-1fc4-44cd-9adb-f2ae31608222

Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort

Autor: George du Toit, Peter H. Sayre, Graham Roberts, Kaitie Lawson, Michelle L. Sever, Henry T. Bahnson, Helen R. Fisher, Mary Feeney, Suzana Radulovic, Monica Basting, Marshall Plaut, Gideon Lack, Susan Chan, Adam Fox, Mable Abraham, Muhsinah Adam, Louise Coverdale, Claire Duncan, Amy Nixon, Una O’Dwyer-Leeson, Victoria Offord, Aine Sheridan, Fiona Watson, Natalie Witham, Kathryn Cockerell, Gail Harland, Tiffany Miller, Charlotte Stedman, Catherine Clarke, Richard Cleaver, Gemma Deutsch, Alicia Parr, Natalia Becares, Matthew Crossley, Natalia do Couto Francisco, Kerry Richards, Ewa Pietraszewicz, Alick Stephens, Asha Sudra, Rianne Wester, Alastair Wilson, Celine Wu, Jenna Heath, Kathryn Hersee, Devi Patkunam, Adam Asare, Eduard Chani, Judith Evind, Noha Lim, Audrey Plough, Margarita Gomez Lorenzo, Joy Laurienzo Panza, Jackie Johnson, Jack Hu, Travis Mason

Publikováno v: du Toit, G, Sayre, P H, Roberts, G, Lawson, K, Sever, M L, Bahnson, H T, Fisher, H R, Feeney, M, Radulovic, S, Basting, M & Plaut, M & Lack, G 2018, ' Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1343-1353 . https://doi.org/10.1016/j.jaci.2017.09.034

BACKGROUND: Early introduction of dietary peanut in high-risk infants with severe eczema, egg allergy, or both prevented peanut allergy at 5 years of age in the Learning Early About Peanut Allergy (LEAP) study. The protective effect persisted after 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764673deadf62c262417ba59510ec80d
https://kclpure.kcl.ac.uk/ws/files/130729194/Allergen_specificity_of_early_DU_TOIT_2017_GOLD_VoR_CC_BY_NC_ND_.pdf

Effect of Avoidance on Peanut Allergy after Early Peanut Consumption

Autor: George, Du Toit, Peter H, Sayre, Graham, Roberts, Michelle L, Sever, Kaitie, Lawson, Henry T, Bahnson, Helen A, Brough, Alexandra F, Santos, Kristina M, Harris, Suzana, Radulovic, Monica, Basting, Victor, Turcanu, Marshall, Plaut, Gideon, Lack, Travis, Mason

Publikováno v: The New England journal of medicine. 374(15)

Background In a randomized trial, the early introduction of peanuts in infants at high risk for allergy was shown to prevent peanut allergy. In this follow-up study, we investigated whether the rate of peanut allergy remained low after 12 months of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4fa12b23df39773bea7b0719d73cb2
https://pubmed.ncbi.nlm.nih.gov/26942922

Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis

Autor: Kristina M. Harris, Nadia K. Tchao, Guy W. Scadding, Florentina A. Dumitru, Kaitie Lawson, Audrey Plough, Joy Laurienzo Panza, Mohamed H. Shamji, Moises A. Calderon, Michelle L. Sever, Stephen R. Durham, Martin Penagos, Alkis Togias, Aarif O. Eifan, Noha Lim, Henry T. Bahnson, Tielin Qin

Publikováno v: JAMA. 317:615

Importance Sublingual immunotherapy and subcutaneous immunotherapy are effective in seasonal allergic rhinitis. Three years of continuous treatment with subcutaneous immunotherapy and sublingual immunotherapy has been shown to improve symptoms for at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01c81b5e363ebe37189bfeb4be4e8e5b
https://doi.org/10.1001/jama.2016.21040