Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Kaitao Li"'
Autor:
Kaitao Li, Paul Cardenas-Lizana, Jintian Lyu, Anna V. Kellner, Menglan Li, Peiwen Cong, Valencia E. Watson, Zhou Yuan, Eunseon Ahn, Larissa Doudy, Zhenhai Li, Khalid Salaita, Rafi Ahmed, Cheng Zhu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Despite the success of PD-1 blockade in cancer therapy, how PD-1 initiates signaling remains unclear. Soluble PD-L1 is found in patient sera and can bind PD-1 but fails to suppress T cell function. Here, we show that PD-1 function is reduced
Externí odkaz:
https://doaj.org/article/202742e2c87c4895aea226594428ba31
Autor:
Xuanwen Hua, Keyi Han, Biagio Mandracchia, Afsane Radmand, Wenhao Liu, Hyejin Kim, Zhou Yuan, Samuel M. Ehrlich, Kaitao Li, Corey Zheng, Jeonghwan Son, Aaron D. Silva Trenkle, Gabriel A. Kwong, Cheng Zhu, James E. Dahlman, Shu Jia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Imaging flow cytometry (IFC) combines flow cytometry and fluorescence microscopy to enable high-throughput, multiparametric single-cell analysis with rich spatial details. However, current IFC techniques remain limited in their ability to re
Externí odkaz:
https://doaj.org/article/4523c0533efd47cd8f5f386a1b3e847a
Autor:
Pingping Sun, Zhan Wang, Sixiao Li, Jiajing Yin, Yuyang Gan, Shizhao Liu, Zhen Lin, Hailin Wang, Zhexiang Fan, Qian Qu, Zhiqi Hu, Kaitao Li, Yong Miao
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Background Hair follicle stem cells (HFSCs) typically remain quiescent and are activated only during the transition from telogen to anagen to ensure that the hair follicle enters a new cycle. The metabolic behavior of stem cells in tissues i
Externí odkaz:
https://doaj.org/article/c785aef046d041329059d4b2174de7f8
Autor:
Ningbo Guo, Mingyong Jiang, Decheng Wang, Yutong Jia, Kaitao Li, Yanan Zhang, Mingdong Wang, Jiancheng Luo
Publikováno v:
Remote Sensing, Vol 16, Iss 18, p 3531 (2024)
Hyperspectral image (HSI) shows great potential for application in remote sensing due to its rich spectral information and fine spatial resolution. However, the high dimensionality, nonlinearity, and complex relationship between spectral and spatial
Externí odkaz:
https://doaj.org/article/198775d14842494cbb1d7891a453e501
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract It remains a great challenge to engineer materials with strong and stable interactions for the simultaneously mechanical-robust and room temperature phosphorescence-efficient materials. In this work, we demonstrate a covalent cross-linking s
Externí odkaz:
https://doaj.org/article/da269ddd1e6549f8a8880447937a98d9
Autor:
Hyun-Kyu Choi, Peiwen Cong, Chenghao Ge, Aswin Natarajan, Baoyu Liu, Yong Zhang, Kaitao Li, Muaz Nik Rushdi, Wei Chen, Jizhong Lou, Michelle Krogsgaard, Cheng Zhu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The TCR integrates forces in its triggering process upon interaction with pMHC. Force elicits TCR catch-slip bonds with strong pMHCs but slip-only bonds with weak pMHCs. We develop two models and apply them to analyze 55 datasets, demonstrat
Externí odkaz:
https://doaj.org/article/f65b7c07a27343aabc7d91d32a2c94ff
Autor:
Muaz Nik Rushdi, Victor Pan, Kaitao Li, Hyun-Kyu Choi, Stefano Travaglino, Jinsung Hong, Fletcher Griffitts, Pragati Agnihotri, Roy A. Mariuzza, Yonggang Ke, Cheng Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
It is known that the T cell co-receptor CD4 greatly enhances the capacity of T cell receptor (TCR) signalling, triggered by the peptide-bound MHC molecule. Here authors show that the mechanistic basis for the enhancement is the co-operative binding o
Externí odkaz:
https://doaj.org/article/2859ebb5eb6e4438bdcbb90534f57bee
Autor:
Yuyang Gan, Hailin Wang, Lijuan Du, Zhexiang Fan, Pingping Sun, Kaitao Li, Qian Qu, Jin Wang, Ruosi Chen, Zhiqi Hu, Yong Miao
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Hair follicle mesenchymal stem cells (HF-MSCs) have great potential for cell therapy. Traditional method to isolate whisker HF-MSC is time-consuming and few in cell numbers. How to quickly and conveniently obtain a large number of
Externí odkaz:
https://doaj.org/article/098563a2c3a24432b9b40d26b45d09c8
Publikováno v:
Molecules, Vol 28, Iss 23, p 7792 (2023)
Poly(vinyl chloride) (PVC) is widely used in various fields and requires the use of thermal stabilizers to enhance its thermal stability during processing because of its poor thermal stability. Layered double hydroxides (LDHs) are widely considered t
Externí odkaz:
https://doaj.org/article/d48690e93b6f4863878a7ef424ab5b0d
Autor:
Ningbo Guo, Mingyong Jiang, Lijing Gao, Kaitao Li, Fengjie Zheng, Xiangning Chen, Mingdong Wang
Publikováno v:
Remote Sensing, Vol 15, Iss 20, p 5044 (2023)
Land-use scene classification (LUSC) is a key technique in the field of remote sensing imagery (RSI) interpretation. A convolutional neural network (CNN) is widely used for its ability to autonomously and efficiently extract deep semantic feature map
Externí odkaz:
https://doaj.org/article/5e51ddea7e714bdea7439e201b236ec8