Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kaitao Lai"'
Publikováno v:
Italian Journal of Pediatrics, Vol 48, Iss 1, Pp 1-9 (2022)
Abstract Background Hypophosphatemic rickets (HR) is a genetic disease of phosphate wasting that is characterized by defective bone mineralization. The most common cause of the disease is mutations in the phosphate regulating gene with homologies to
Externí odkaz:
https://doaj.org/article/73e28aa11fc140a2a05a2fa441b2330c
Publikováno v:
Journal of Investigative Surgery, Vol 35, Iss 5, Pp 1135-1144 (2022)
Intervertebral disk (IVD) degeneration (IVDD) can cause various spinal degenerative diseases. Cumulative evidence has indicated that IVDD can result from inflammation, apoptosis, autophagy, biomechanical changes and other factors. Currently, lack of
Externí odkaz:
https://doaj.org/article/dbd4eeb25fcf4393889ff989b07a2ddb
Autor:
Ji Tu, Wentian Li, Sidong Yang, Pengyi Yang, Qi Yan, Shenyu Wang, Kaitao Lai, Xupeng Bai, Cenhao Wu, Wenyuan Ding, Justin Cooper‐White, Ashish Diwan, Cao Yang, Huilin Yang, Jun Zou
Publikováno v:
Advanced Science, Vol 9, Iss 3, Pp n/a-n/a (2022)
Abstract Although degeneration of the nucleus pulposus (NP) is a major contributor to intervertebral disc degeneration (IVDD) and low back pain, the underlying molecular complexity and cellular heterogeneity remain poorly understood. Here, a comprehe
Externí odkaz:
https://doaj.org/article/54cfcdd39928432bb8ac08c9bff21ef5
Autor:
Alvaro Gonzalez Rajal, Kamila A Marzec, Rachael A McCloy, Max Nobis, Venessa Chin, Jordan F Hastings, Kaitao Lai, Marina Kennerson, William E Hughes, Vijesh Vaghjiani, Paul Timpson, Jason E Cain, D Neil Watkins, David R Croucher, Andrew Burgess
Publikováno v:
eLife, Vol 10 (2021)
We previously used a pulse-based in vitro assay to unveil targetable signalling pathways associated with innate cisplatin resistance in lung adenocarcinoma (Hastings et al., 2020). Here, we advanced this model system and identified a non-genetic mech
Externí odkaz:
https://doaj.org/article/2218265a2a26450eb03d27ef3e339032
Autor:
Edward Abadir, Robin E. Gasiorowski, Kaitao Lai, Fiona Kupresanin, Adelina Romano, Pablo A. Silveira, Tsun‐Ho Lo, Phillip D. Fromm, Marina L. Kennerson, Harry J. Iland, P. Joy Ho, P. Mark Hogarth, Kenneth Bradstock, Derek N.J. Hart, Georgina J. Clark
Publikováno v:
Molecular Oncology, Vol 13, Iss 10, Pp 2107-2120 (2019)
Antibody‐based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs). Achieving greater success with therapeutic antibodies requires care
Externí odkaz:
https://doaj.org/article/45bf9c7fc9c74c24a8afac22a249fba2
Publikováno v:
PeerJ, Vol 6, p e5648 (2018)
Eucalyptus is harvested for wood and fiber production in many tropical and sub-tropical habitats globally. Plantation has been controversial because of its influence on the surrounding environment, however, the influence of massive Eucalyptus plantin
Externí odkaz:
https://doaj.org/article/6acc123375fa4f1ebd2c67b742c1186c
Autor:
Thomas C. Jeffries, Smriti Rayu, Uffe N. Nielsen, Kaitao Lai, Ali Ijaz, Loic Nazaries, Brajesh K. Singh
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Chemical contamination of natural and agricultural habitats is an increasing global problem and a major threat to sustainability and human health. Organophosphorus (OP) compounds are one major class of contaminant and can undergo microbial degradatio
Externí odkaz:
https://doaj.org/article/c074c62018a04159b4ed73e6e3b066db
Autor:
Jacqueline Batley, Kaitao Lai, Paul J. Berkman, Paul Visendi, Pradeep Ruperao, Sahana Manoli, Jiri Stiller, Hong Lee, Satomi Hayashi, Michał T. Lorenc, David Edwards
Publikováno v:
Biology, Vol 1, Iss 2, Pp 370-382 (2012)
Single nucleotide polymorphisms (SNPs) are becoming the dominant form of molecular marker for genetic and genomic analysis. The advances in second generation DNA sequencing provide opportunities to identify very large numbers of SNPs in a range of sp
Externí odkaz:
https://doaj.org/article/8af13cb1b2e34b8e8de0e5d134f85403
Publikováno v:
Agronomy, Vol 2, Iss 1, Pp 62-73 (2012)
Genomics is playing an increasing role in plant breeding and this is accelerating with the rapid advances in genome technology. Translating the vast abundance of data being produced by genome technologies requires the development of custom bioinforma
Externí odkaz:
https://doaj.org/article/975d21b6abff41869f7df914597eefcc
Publikováno v:
Journal of Investigative Surgery. 35:1135-1144
Intervertebral disk (IVD) degeneration (IVDD) can cause various spinal degenerative diseases. Cumulative evidence has indicated that IVDD can result from inflammation, apoptosis, autophagy, biomechanical changes and other factors. Currently, lack of