Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study

Autor: Laaksonen, L., Kallioinen, M., Långsjö, J., Laitio, T., Scheinin, A., Scheinin, J., Kaisti, K., Maksimow, A., Kallionpää, R.E., Rajala, V., Johansson, J., Kantonen, O., Nyman, M., Sirén, S., Valli, K., Revonsuo, A., Solin, O., Vahlberg, T., Alkire, M., Scheinin, H.

Publikováno v: In British Journal of Anaesthesia July 2018 121(1):281-290

Wide inter-individual variability of bispectral index and spectral entropy at loss of consciousness during increasing concentrations of dexmedetomidine, propofol, and sevoflurane

Autor: Kaskinoro, K., Maksimow, A., Långsjö, J., Aantaa, R., Jääskeläinen, S., Kaisti, K., Särkelä, M., Scheinin, H.

Publikováno v: In British Journal of Anaesthesia October 2011 107(4):573-580

Decreased Thalamic Activity Is a Correlate for Disconnectedness during Anesthesia with Propofol, Dexmedetomidine and Sevoflurane But Not S-Ketamine.

Autor: Kantonen O; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Satakunta Central Hospital, Pori FI-28500, Finland., Laaksonen L; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Alkire M; Department of Anesthesiology and Perioperative Medicine, University of California, Irvine, Irvine, California 92868., Scheinin A; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Långsjö J; Department of Intensive Care, Tampere University Hospital, Tampere FI-33521, Finland., Kallionpää RE; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turun yliopisto FI-20014, Finland., Kaisti K; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Anesthesiology and Intensive Care, Oulu University Hospital, Oulu FI-90029, Finland., Radek L; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland., Johansson J; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Radiation Sciences, Umeå University, Umeå SE-901 87, Sweden., Laitio T; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Maksimow A; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Scheinin J; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Nyman M; Department of Radiology, Turku University Hospital, Turku FI-20521, Finland., Scheinin M; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, Turun yliopisto FI-20014, Finland., Solin O; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland., Vahlberg T; Institute of Clinical Medicine, Biostatistics, University of Turku and Turku University Hospital, Turun yliopisto FI-20014, Finland., Revonsuo A; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turun yliopisto FI-20014, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde SE-541 28, Sweden., Valli K; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turun yliopisto FI-20014, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde SE-541 28, Sweden., Scheinin H; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland harry.scheinin@utu.fi.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, Turun yliopisto FI-20014, Finland.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2023 Jun 28; Vol. 43 (26), pp. 4884-4895. Date of Electronic Publication: 2023 May 24.

Circulating oxylipin and bile acid profiles of dexmedetomidine, propofol, sevoflurane, and S-ketamine: a randomised controlled trial using tandem mass spectrometry.

Autor: Nummela A; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.; Department of Internal Medicine, Turku University Hospital, Turku, Finland., Laaksonen L; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.; Department of Peri-operative Services, University of Turku and Turku University Hospital, Turku, Finland., Scheinin A; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.; Department of Peri-operative Services, University of Turku and Turku University Hospital, Turku, Finland., Kaisti K; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.; Department of Peri-operative Services, University of Turku and Turku University Hospital, Turku, Finland., Vahlberg T; Department of Clinical Medicine, Biostatistics, Intensive Care and Pain Medicine, University of Turku and Turku University Hospital, Turku, Finland., Neuvonen M; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Valli K; Department of Peri-operative Services, University of Turku and Turku University Hospital, Turku, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turku, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde, Sweden., Revonsuo A; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turku, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde, Sweden., Perola M; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Finnish Institute for Health and Welfare, Helsinki, Finland., Niemi M; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland., Scheinin H; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.; Department of Peri-operative Services, University of Turku and Turku University Hospital, Turku, Finland.; Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland., Laitio T; Department of Peri-operative Services, University of Turku and Turku University Hospital, Turku, Finland.

Publikováno v: BJA open [BJA Open] 2022 Dec 12; Vol. 4, pp. 100114. Date of Electronic Publication: 2022 Dec 12 (Print Publication: 2022).

Foundations of Human Consciousness: Imaging the Twilight Zone.

Autor: Scheinin A; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland., Kantonen O; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland., Alkire M; University of California, Irvine, Irvine, California 92868., Långsjö J; Department of Intensive Care, Tampere University Hospital, FI-33521 Tampere, Finland., Kallionpää RE; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland., Kaisti K; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland.; Department of Anesthesiology and Intensive Care, Oulu University Hospital, FI-90029 Oulu, Finland., Radek L; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland., Johansson J; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland.; Department of Radiation Sciences, Umeå University, 901 87 Umeå, Sweden., Sandman N; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland., Nyman M; Department of Radiology, Turku University Hospital, FI-0521 Turku, Finland., Scheinin M; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, FI-20014 Turun yliopisto, Finland., Vahlberg T; Institute of Clinical Medicine, Biostatistics, University of Turku and Turku University Hospital, FI-20014 Turun yliopisto, Finland., Revonsuo A; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, 541 28 Skövde, Sweden., Valli K; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, 541 28 Skövde, Sweden., Scheinin H; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland harry.scheinin@utu.fi.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, FI-20014 Turun yliopisto, Finland.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Feb 24; Vol. 41 (8), pp. 1769-1778. Date of Electronic Publication: 2020 Dec 28.