Human Islet Expression Levels of Prostaglandin E 2 Synthetic Enzymes, But Not Prostaglandin EP3 Receptor, Are Positively Correlated with Markers of β-Cell Function and Mass in Nondiabetic Obesity.

Autor: Truchan NA; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Fenske RJ; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States.; Interdepartmental Graduate Program in Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Sandhu HK; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Weeks AM; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Patibandla C; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Wancewicz B; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States., Pabich S; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States., Reuter A; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Harrington JM; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Brill AL; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Peter DC; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Nall R; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Daniels M; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Punt M; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States., Kaiser CE; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States., Cox ED; Department of Pediatrics, University of Wisconsin-Madison, Madison, Wisconsin 53792, United States., Ge Y; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Davis DB; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States.; Interdepartmental Graduate Program in Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States., Kimple ME; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.; Research Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, United States.; Interdepartmental Graduate Program in Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2021 Jun 16; Vol. 4 (4), pp. 1338-1348. Date of Electronic Publication: 2021 Jun 16 (Print Publication: 2021).

Molecular genomic and epigenomic characteristics related to aspirin and clopidogrel resistance.

Autor: Kim, Jei^1,2 (AUTHOR) jeikim@cnu.ac.kr, Shin, Byoung-Soo³ (AUTHOR), Kim, Dae-Hyun⁴ (AUTHOR), Shin, Dong-Ick⁵ (AUTHOR), Ahn, Seong Hwan⁶ (AUTHOR), Kim, Jae Guk⁷ (AUTHOR), Ryu, Su Hyun¹ (AUTHOR), Moon, Hye Rin¹ (AUTHOR), Kang, Hyun Goo³ (AUTHOR), Jeong, Hyeseon¹ (AUTHOR), Yum, Kyu Sun⁵ (AUTHOR), Chae, Hee-Yun⁵ (AUTHOR), Kim, Do-Hyung⁷ (AUTHOR), Kang, Keunsoo⁸ (AUTHOR), Kim, Jeeyeon¹ (AUTHOR)

Publikováno v: BMC Medical Genomics. 6/20/2024, Vol. 17 Issue 1, p1-12. 12p.

Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression.

Autor: Kaiser CE; College of Pharmacy, University of Arizona , Tucson, Arizona 85721, United States., Van Ert NA; College of Pharmacy, University of Arizona , Tucson, Arizona 85721, United States., Agrawal P; College of Pharmacy, University of Arizona , Tucson, Arizona 85721, United States., Chawla R; BIO5 Institute, University of Arizona , Tucson, Arizona 85721, United States., Yang D; College of Pharmacy, University of Arizona , Tucson, Arizona 85721, United States.; University of Arizona Cancer Center, University of Arizona , Tucson, Arizona 85724, United States.; BIO5 Institute, University of Arizona , Tucson, Arizona 85721, United States., Hurley LH; College of Pharmacy, University of Arizona , Tucson, Arizona 85721, United States.; University of Arizona Cancer Center, University of Arizona , Tucson, Arizona 85724, United States.; BIO5 Institute, University of Arizona , Tucson, Arizona 85721, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2017 Jun 28; Vol. 139 (25), pp. 8522-8536. Date of Electronic Publication: 2017 Jun 15.

Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?

Autor: Broos, Jelle Y.^1,2,3 (AUTHOR), van der Burgt, Rianne T. M.^1,2 (AUTHOR), Konings, Julia^1,2,4,5 (AUTHOR), Rijnsburger, Merel^1,2,4,6 (AUTHOR), Werz, Oliver⁷ (AUTHOR), de Vries, Helga E.^1,4 (AUTHOR), Giera, Martin³ (AUTHOR), Kooij, Gijs^1,2,4,5 (AUTHOR) g.kooij@amsterdamumc.nl

Publikováno v: Journal of Neuroinflammation. 1/17/2024, Vol. 21 Issue 1, p1-20. 20p.

Molecular docking and molecular dynamics simulation studies reveal repurposing I-Motif ligand as a promising protease inhibitor against SARS-CoV-2 variants.

Autor: Prompat, Napat, Nadee, Panik, Phongdara, Amornrat, Nualla-ong, Aekkaraj

Publikováno v: Molecular Simulation; Nov2024, Vol. 50 Issue 16, p1354-1366, 13p