Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Kaisa Salmenkivi"'
Autor:
Tiina Vesterinen, Teijo Kuopio, Maarit Ahtiainen, Aija Knuuttila, Harri Mustonen, Kaisa Salmenkivi, Johanna Arola, Caj Haglund
Publikováno v:
Endocrine Connections, Vol 8, Iss 8, Pp 1168-1175 (2019)
Pulmonary carcinoid (PC) tumors are rare tumors that account for approximately 1% of all lung cancers. The primary treatment option is surgery, while there is no standard treatment for metastatic disease. As the number of PCs diagnosed yearly is incr
Externí odkaz:
https://doaj.org/article/5b1ff3d49b504214a7d5c370ca7bc6d7
Autor:
Eeva Kettunen, Sauli Savukoski, Kaisa Salmenkivi, Tom Böhling, Esa Vanhala, Eeva Kuosma, Sisko Anttila, Henrik Wolff
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Deletion of the CDKN2A locus is centrally involved in the development of several malignancies. In malignant pleural mesothelioma (MPM), it is one of the most frequently reported genomic alteration. MPM is strongly associated with
Externí odkaz:
https://doaj.org/article/131cca9545364481bce20e538437397f
Autor:
Ashwini S. Nagaraj, Jenni Lahtela, Annabrita Hemmes, Teijo Pellinen, Sami Blom, Jennifer R. Devlin, Kaisa Salmenkivi, Olli Kallioniemi, Mikko I. Mäyränpää, Katja Närhi, Emmy W. Verschuren
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 673-684 (2017)
Lung cancers exhibit pronounced functional heterogeneity, confounding precision medicine. We studied how the cell of origin contributes to phenotypic heterogeneity following conditional expression of KrasG12D and loss of Lkb1 (Kras;Lkb1). Using proge
Externí odkaz:
https://doaj.org/article/4865c03d589649f090200e998d1e2cd4
Autor:
Emmy W. Verschuren, Krister Wennerberg, Mikko I. Mäyränpää, Kaisa Salmenkivi, Pipsa Saharinen, Elina A. Kiss, Swapnil Potdar, Annabrita Hemmes, Jennifer R. Devlin, Ashwini S. Nagaraj, Sarang S. Talwelkar
Table_S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4275035dd0425cbf4d4e396a83cab57f
https://doi.org/10.1158/1535-7163.22509204
https://doi.org/10.1158/1535-7163.22509204
Autor:
Emmy W. Verschuren, Krister Wennerberg, Mikko I. Mäyränpää, Kaisa Salmenkivi, Pipsa Saharinen, Elina A. Kiss, Swapnil Potdar, Annabrita Hemmes, Jennifer R. Devlin, Ashwini S. Nagaraj, Sarang S. Talwelkar
Supplementary text and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25da8709577071f02aaeaf9cd8b88369
https://doi.org/10.1158/1535-7163.22509210.v1
https://doi.org/10.1158/1535-7163.22509210.v1
Autor:
Emmy W. Verschuren, Krister Wennerberg, Mikko I. Mäyränpää, Kaisa Salmenkivi, Pipsa Saharinen, Elina A. Kiss, Swapnil Potdar, Annabrita Hemmes, Jennifer R. Devlin, Ashwini S. Nagaraj, Sarang S. Talwelkar
Most non–small cell lung cancers (NSCLC) contain nontargetable mutations, including KRAS, TP53, or STK11/LKB1 alterations. By coupling ex vivo drug sensitivity profiling with in vivo drug response studies, we aimed to identify drug vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d26d521c92c9d7c4073c63d907f5285
https://doi.org/10.1158/1535-7163.c.6539226.v1
https://doi.org/10.1158/1535-7163.c.6539226.v1
Autor:
Pipsa Saharinen, Swapnil Potdar, Jennifer R. Devlin, Emmy W. Verschuren, Elina A. Kiss, Kaisa Salmenkivi, Ashwini S. Nagaraj, Annabrita Hemmes, Krister Wennerberg, Sarang S. Talwelkar, Mikko I. Mäyränpää
Publikováno v:
Talwelkar, S S, Nagaraj, A S, Devlin, J R, Hemmes, A, Potdar, S, Kiss, E A, Saharinen, P, Salmenkivi, K, Mäyränpää, M I, Wennerberg, K & Verschuren, E W 2019, ' Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify Kras-Mutant Lung Cancers ', Molecular Cancer Therapeutics, vol. 18, no. 10, pp. 1863-1874 . https://doi.org/10.1158/1535-7163.MCT-18-0573
Most non–small cell lung cancers (NSCLC) contain nontargetable mutations, including KRAS, TP53, or STK11/LKB1 alterations. By coupling ex vivo drug sensitivity profiling with in vivo drug response studies, we aimed to identify drug vulnerabilities
Autor:
Mikko I. Mäyränpää, Emmy W. Verschuren, John Le Quesne, Ana Teodósio, Nora Linnavirta, Annabrita Hemmes, Kaisa Salmenkivi, Katja Närhi, Jie Bao
The transcription factor SOX9 is a key regulator of multiple developmental processes and is frequently re-expressed in non-small cell lung cancer (NSCLC). Its precise role in the progression of NSCLC histotypes has, however, remained elusive. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65e8f560d60ce3a7cba5a9afdb7268e
https://www.repository.cam.ac.uk/handle/1810/324129
https://www.repository.cam.ac.uk/handle/1810/324129
Autor:
Caj Haglund, Elisa Lappi-Blanco, Tiina Vesterinen, Teijo Kuopio, Harri Mustonen, Kaisa Salmenkivi, Olli Carpén, Paula Vainio, Timo Paavonen, Aija Knuuttila, Johanna Arola
Publikováno v:
Virchows Archiv
Finnish hospital-integrated biobanks administer millions of formalin-fixed paraffin-embedded tissue samples collected within the clinical diagnostics. According to the Finnish Biobank Act, these samples can be coupled with patients’ clinical follow
Autor:
Ana Teodósio, John Le Quesne, Emmy W. Verschuren, Jie Bao, Katja Närhi, Kaisa Salmenkivi, Annabrita Hemmes, Mikko I. Mäyränpää, Nora Linnavirta
The transcription factor SOX9 is a key regulator of multiple developmental processes, and is frequently re-expressed in non-small cell lung cancer (NSCLC). Its precise role in the progression of NSCLC histopathologies has however remained elusive. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1742f5525a63fbd8dcf335a3756b41c
https://doi.org/10.1101/2020.11.23.393926
https://doi.org/10.1101/2020.11.23.393926