Zobrazeno 1 - 10 of 84 pro vyhledávání: '"Kaisa M. Mäki‐Petäjä"'
1
Akademický článek
Quantitative 18F-fluorodeoxyglucose positron emission tomography/computed tomography to assess pulmonary inflammation in COPD
Autor: Laurence Vass, Marie Fisk, Joseph Cheriyan, Divya Mohan, Julia Forman, Adelola Oseni, Anand Devaraj, Kaisa M. Mäki-Petäjä, Carmel M. McEniery, Jonathan Fuld, Nicholas S. Hopkinson, David A. Lomas, John R. Cockcroft, Ruth Tal-Singer, Michael I. Polkey, Ian B. Wilkinson
Publikováno v: ERJ Open Research, Vol 7, Iss 3 (2021)
Rationale COPD and smoking are characterised by pulmonary inflammation. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) imaging may improve knowledge of pulmonary inflammation in COPD patients and aid early develo
Externí odkaz: https://doaj.org/article/58b7ac41c79543efbd700168d5af6a88
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2
Akademický článek
Cardiovascular risk prediction using physical performance measures in COPD: results from a multicentre observational study
Autor: Divya Mohan, Carmel M McEniery, John R Cockcroft, William MacNee, Jonathan Fuld, Marie Fisk, Joseph Cheriyan, Ruth Tal-Singer, Ian B Wilkinson, Michael I Polkey, Jilles M Fermont, Hana Müllerova, Angela M Wood, Charlotte E Bolton, Kaisa M Mäki-Petäjä, Ali B Al-Hadithi
Publikováno v: BMJ Open, Vol 10, Iss 12 (2020)
Objectives Although cardiovascular disease (CVD) is a common comorbidity associated with chronic obstructive pulmonary disease (COPD), it is unknown how to improve prediction of cardiovascular (CV) risk in individuals with COPD. Traditional CV risk s
Externí odkaz: https://doaj.org/article/28be3a2dbdbf48adb16eaad8e2b66add
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3
Akademický článek
The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised double-blind placebo-controlled trial.
Autor: Marie Fisk, Joseph Cheriyan, Divya Mohan, Julia Forman, Kaisa M Mäki-Petäjä, Carmel M McEniery, Jonathan Fuld, James H F Rudd, Nicholas S Hopkinson, David A Lomas, John R Cockcroft, Ruth Tal-Singer, Michael I Polkey, Ian B Wilkinson
Publikováno v: PLoS ONE, Vol 13, Iss 3, p e0194197 (2018)
BackgroundCardiovascular disease is a major cause of morbidity and mortality in COPD patients. Systemic inflammation associated with COPD, is often hypothesised as a causal factor. p38 mitogen-activated protein kinases play a key role in the inflamma
Externí odkaz: https://doaj.org/article/b8081b2e4dcf46128fb118fce2ecb2ca
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4
Akademický článek
Tetrahydrobiopterin Supplementation Improves Endothelial Function But Does Not Alter Aortic Stiffness in Patients With Rheumatoid Arthritis
Autor: Kaisa M. Mäki‐Petäjä, Lisa Day, Joseph Cheriyan, Frances C. Hall, Andrew J. K. Östör, Nicholas Shenker, Ian B. Wilkinson
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundRheumatoid arthritis is a systemic inflammatory condition associated with increased cardiovascular risk that may be due to underlying endothelial dysfunction and subsequent aortic stiffening. We hypothesized that supplementation with tetrah
Externí odkaz: https://doaj.org/article/a63a8cba920e40c0936f74d50ed32d10
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5
Uses of Arterial Stiffness in Clinical Practice
Autor: Gary F. Mitchell, Ian B. Wilkinson, Kaisa M. Mäki-Petäjä
Publikováno v: Arterioscler Thromb Vasc Biol
As far back as the ancient Egyptians and Greeks, physicians have observed and interpreted the arterial pulse to diagnose disease. In the last 20 years, advances in modern engineering have rendered quantitative pulse wave analysis widely available, re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd58400e62753ca23f5df402e7d3bc67
https://doi.org/10.1161/atvbaha.120.313130
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7
Akademický článek
Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial.
Autor: Parag R Gajendragadkar, Annette Hubsch, Kaisa M Mäki-Petäjä, Martin Serg, Ian B Wilkinson, Joseph Cheriyan
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e99070 (2014)
AIMS:The mechanisms by which a 'Mediterranean diet' reduces cardiovascular disease (CVD) burden remain poorly understood. Lycopene is a potent antioxidant found in such diets with evidence suggesting beneficial effects. We wished to investigate the e
Externí odkaz: https://doaj.org/article/251aab55edbc4be78c8836ae9f699b27
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8
Mechanisms Underlying Vascular Endothelial Growth Factor Receptor Inhibition-Induced Hypertension – The Hypaz Trial
Autor: Ian B. Wilkinson, Carola-Bibiane Schönlieb, Sara Santos Franco, Yoeri E. Boink, Christoph Brune, Annette Hubsch, Adam McGeoch, Lucy Yang, Fraz Mir, Simon Bond, Carmel M. McEniery, Nicola Ramenatte, Duncan I. Jodrell, Kaisa M. Mäki-Petäjä, Gayathri Anandappa, Joseph Cheriyan, Paul A R Meyer, Parag R Gajendragadkar
Publikováno v: Hypertension
Hypertension, 77(5), 1591-1599. Lippincot, Williams & Wilkins
Drugs targeting the VEGF (vascular endothelial growth factor) signaling pathway are approved for several malignancies. Unfortunately, VEGF inhibitors lead to hypertension in 30% to 80% patients. Reduced nitric oxide synthase activity, microvascular r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755d8a0ee36ffb6c589f28eef9112952
https://europepmc.org/articles/PMC7610566/
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10
Vascular consequences of inflammation: a position statement from the ESH Working Group on Vascular Structure and Function and the ARTERY Society
Autor: Pierre Boutouyrie, Bart Spronck, Athanase D. Protogerou, Philippe Bouchard, Marie Briet, Alain Tedgui, Ernesto L. Schiffrin, Pedro Cunha, Kaisa M. Mäki-Petäjä, Jean Philippe Empana, Rhian M. Touyz, Charalambos Vlachopoulos, Luca Zanoli, Rosa Maria Bruno
Publikováno v: Journal of Hypertension
Journal of Hypertension, 38(9), 1682-1698. LIPPINCOTT WILLIAMS & WILKINS
J Hypertens
Inflammation is a physiological response to aggression of pathogenic agents aimed at eliminating the aggressor agent and promoting healing. Excessive inflammation, however, may contribute to tissue damage and an alteration of arterial structure and f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c543a848998e69bba03e05fec726fd4
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