Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kaisa Ketomäki"'
Publikováno v:
Bioconjugate Chemistry. 18:1583-1592
Functionalized 2'-O-methyl oligoribonucleotides bearing two 3-(3-hydroxypropyl)-1,5,9-triazacyclododecane ligands attached via a phosphodiester linkage to a single non-nucleosidic building block have been prepared on a solid-support by conventional p
Autor:
Kaisa Ketomäki, Harri Lönnberg
Publikováno v:
Bioconjugate Chemistry. 17:1063-1068
A mixed-phase immunoassay based on simultaneous binding of an antibody to its fluorescently tagged peptide epitope and a PNA conjugate of the same peptide has been developed. As a fluorescent marker, a europium(III) chelate allowing time-resolved mea
Autor:
Kaisa Ketomäki, Harri Lönnberg, Piia Penttinen, Elena Azhayeva, Tuula Tennilä, Unni Tengvall, Alex Azhayev, Seppo Auriola
Publikováno v:
Chemistry & Biodiversity. 1:609-625
The synthesis of disulfide-cross-linked circular oligonucleotides, employing two different approaches, was accomplished. Several circular oligomers, which bear a C(5)-aminoalkyl-tethered thymidine unit, were labeled with photoluminescent europium(III
Publikováno v:
Bioconjugate Chemistry. 13:542-547
Hybridization of short oligonucleotides (10- and 11-mers) to complementary probes immobilized to microscopic polymer particles was quantified by a sandwich type mixed-phase hybridization assay based on a time-resolved fluorometric measurement of a ph
Autor:
Satu Mikkola, Niangoran Koissi, Kaisa Ketomäki, Harri Lönnberg, Kari Neuvonen, Susanna Rauvala
Publikováno v:
European Journal of Organic Chemistry. 2000:2315-2323
Reactions of adenosine nucleosides with halogen substituted acetaldehydes and malonaldehydes have been studied and pseudo first-order rate constants have been determined. All the reactions yield 1,N6-etheno adducts, and with malonaldehydes, in additi
Autor:
Kaisa Ketomäki, Pasi Virta
Publikováno v:
Bioconjugate chemistry. 19(3)
Aminoglycoside conjugates of 2'- O-methyl oligoribonucleotides have been synthesized entirely on a solid phase using conventional phosphoramidate chemistry. For this purpose, appropriately protected neamine-derived phosphoramidites, viz., 2-cyanoethy
Autor:
Harri Lönnberg, Satu Mikkola, Ewelina Leino, Qi Wang, Pasi Virta, Kaisa Ketomäki, Tamás Gajda, Istvan Szilagyi, Teija Niittymäki, Päivi Poijärvi-Virta, Attila Jancsó
Publikováno v:
Collection Symposium Series.
Publikováno v:
Collection Symposium Series.
Autor:
Kaisa, Ketomäki, Harri, Lönnberg
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 381
A protocol for quantification of oligonucleotide hybridization on polymer microparticles by europium(III) ion fluorescence is described. The procedure involves modification of commercially available amino-functionalized microparticles in such a manne