Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kaire Heilman"'
Autor:
Efe Ergür, Ege Ergür, Kristi Alnek, Kaja Metsküla, Aleksandr Peet, Maire Lubi, Kaire Heilman, Raivo Uibo
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 2, Pp 221-229 (2023)
Abstract Aims/Introduction We aimed to assess the distribution of transcription factor 7‐like 2 gene TCF7L2 (rs7903146) polymorphism and to find possible associations between TCF7L2 and the characteristics of type 1 diabetes. Materials and Methods
Externí odkaz:
https://doaj.org/article/5ea8f622d87d4c5b9bf2ea05c40b138f
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0142976 (2015)
The production of several cytokines could be dysregulated in type 1 diabetes (T1D). In particular, the activation of T helper (Th) type 1 (Th1) cells has been proposed to underlie the autoimmune pathogenesis of the disease, although roles for inflamm
Externí odkaz:
https://doaj.org/article/32f719be50344466ae4d072115b778fe
Autor:
Efe Ergür, Ege Ergür, Kristi Alnek, Kaja Metsküla, Aleksandr Peet, Maire Lubi, Kaire Heilman, Raivo Uibo
Publikováno v:
Journal of diabetes investigationREFERENCES.
We aimed to assess the distribution of transcription factor 7-like 2 gene TCF7L2 (rs7903146) polymorphism and to find possible associations between TCF7L2 and the characteristics of type 1 diabetes.We studied 190 newly diagnosed type 1 diabetes patie
Autor:
Kaire Heilman, Karin Varik, Aleksandr Peet, Kristi Alnek, Raivo Uibo, Katrin Pruul, Kaja Metsküla, Kalle Kisand
Publikováno v:
Human Immunology
Type-1 diabetes (T1D) is caused by T-cell mediated autoimmune reaction directed against the insulin-secreting beta cells. We hypothesized that in addition to antigen/MHC recognition the co-stimulatory B7 and CD28 pathway is also strongly affected in
Autor:
Tamara Vorobjova, Raivo Uibo, Lumme Kadaja, Oivi Uibo, Kaire Heilman, Helerin Raikkerus, Ija Talja
Publikováno v:
Digestive diseases and sciences. 62(2)
Impaired intestinal integrity, including increased permeability of the small bowel mucosa, has been shown in patients with celiac disease (CD) as well as with type 1 diabetes (T1D). Zonulin (ZO, pre-haptoglobin), a tight junction regulator, plays a p
Autor:
Raivo Uibo, Ivi Ojakivi, Tamara Vorobjova, Oivi Uibo, Kaupo Teesalu, Kaire Heilman, Marina Panarina
Publikováno v:
International Archives of Allergy and Immunology. 156:451-461
Background: The role of regulatory T cells expressing FOXP3 in the pathogenesis of coeliac disease (CD) and type 1 diabetes (T1D) has been reported. Recent data have placed special focus on the interplay between the intestinal barrier and immunoregul
Autor:
Jean-François Nicolas, Asghar Aghamohammadi, Zehra Oya Uyguner, Jan Walter Schroeder, P. Schöpf, G. Sahin, Tamara Vorobjova, Ferhan Özşeker, Mahroo Mirahmadian, M. Russello, Nima Rezaei, T. Herzinger, Gül Karakaya, Satz Mengensatzproduktion, M. Pagani, Shiro Amano, A. Antico, Sarah Abolmaali, Julia Rodriguez, Junichiro Morioka, Annice Heratizadeh, Sara Pasqualetti, Kaupo Teesalu, Franco Frati, Mikiro Mori, Carmen Burbano, Murat Dal, Kazumi Kodaira, Tomohiko Usui, Diana Mamerow, Joseph Haddad, Cristoforo Incorvaia, Hiromi Yano, Hironori Sagara, Karim Allaf, Philippe Moingeon, J. Mullol, Kenya Kohyama, Bahattin Çolakoğlu, Chi-Chih Huang, Takao Nagano, Shyuzo Abe, Bertrand Dubois, Nihal Mete Gökmen, Füsun Erdenen, Ambra Mascheri, Mohammad Biglari, Michele Nichelatti, E. Compalati, Chao-Chien Wu, Tsu-Nai Wang, Meng-Chih Lin, Marina Panarina, Okan Gülbahar, Dominique Kaiserlian, Motohiro Kurosawa, Tung-Heng Wang, Christophe Dercamp, Mercedes M. Pedrosa, Mamoru Tanaka, Hideharu Funatsu, Ming-Shyan Huang, Maryam Tabatabaeiyan, Hiroaki Inamura, Tsu-Yu Yuan, Laura Farioli, Thomas Werfel, Elide A. Pastorello, Alessandro Marocchi, Mercedes Muzquiz, Shao-Hua Lu, Laura Primavesi, Tatsuo Yukawa, Ying-Chin Ko, F. Ruëff, Valerio Pravettoni, Aytül Sin, Li-Ling Yang, Reem Kanjarawi, Chrysi Stafylaraki, Karine Adel-Patient, Soichiro Hozawa, Yasuko Kato, L.E. Walther, Hossein Asgarian-Omran, Imke Satzger, Kaire Heilman, O. Pfaar, Marina Mauro, Kasra Moazzami, Ömür Ardeniz, Ivi Ojakivi, Mayumi Ota, K. Hörmann, Ken Haruma, B. Przybilla, G. Passalacqua, Yen-Hsiung Liao, Jesus F. Crespo, L. Klimek, Claude André, Belgin Kesim, Nathalie Etchart, P.P. Vescovi, Tatsuya Mimura, Aslı Gelincik, Gianbattista Gazzola, Druck Reinhardt Druck Basel, Chin-Chou Wang, Oivi Uibo, Hidetaka Noma, Hassan Abolhassani, Linda Borgonovo, Raivo Uibo, Nima Parvaneh, Beatriz Cabanillas, Marta Piantanida, Margarete Niebuhr, Suna Büyüköztürk, Lawrence B. Schwartz, Joseph Scibilia, Carmen Cuadrado
Publikováno v:
International Archives of Allergy and Immunology. 156:I-IV
Autor:
Vallo Tillmann, Natalja Liivak, Ülle Einberg, Riina Šor, Tuuli Teeäär, Pille Kool, Kaire Heilman, Mare Paal
Publikováno v:
Pediatric Diabetes. 11:107-110
Teeaar T, Liivak N, Heilman K, Kool P, Sor R, Paal M, Einberg U, Tillmann V. Increasing incidence of childhood-onset type 1 diabetes mellitus among Estonian children in 1999–2006. Time trend analysis 1983–2006. Background: The incidence of childh
Autor:
Chris Pruunsild, Hille Liivamägi, Vallo Tillmann, Karin Uibo, Tiina Talvik, Kaire Heilman, Kersti Zilmer, Mihkel Zilmer
Publikováno v:
Open Medicine, Vol 5, Iss 1, Pp 36-40 (2010)
To examine the plasma levels of MPO in oligoarthritis and polyarthritis subtypes of JIA in comparison with healthy age-matched controls. Thirty-eight JIA patients (25 girls and 13 boys) aged 9.1–11.8 years and 23 healthy controls (8 girls and 15 bo
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 69:85-91
Type 1 diabetes has a bad prognosis concerning the pathogenesis of cardiovascular diseases (CVD). The purpose of this study was to evaluate different possible new risk indices for CVD in children with type 1 diabetes.The present study included 30 chi