Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kairbaan M, Hodivala-Dilke"'
Autor:
Tanguy Lechertier, Louise E. Reynolds, Hyojin Kim, Ana Rita Pedrosa, Jesús Gómez-Escudero, José M. Muñoz-Félix, Silvia Batista, Matthew Dukinfield, Fevzi Demircioglu, Ping Pui Wong, Kylie P. Matchett, Neil C. Henderson, Gabriela D’Amico, Maddy Parsons, Catherine Harwood, Pascal Meier, Kairbaan M. Hodivala-Dilke
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/33e6176c6d6a4fc595fff02b19cc1f2f
Autor:
Tanguy Lechertier, Louise E. Reynolds, Hyojin Kim, Ana Rita Pedrosa, Jesús Gómez-Escudero, José M. Muñoz-Félix, Silvia Batista, Matthew Dukinfield, Fevzi Demircioglu, Ping Pui Wong, Kylie P. Matchett, Neil C. Henderson, Gabriela D’Amico, Maddy Parsons, Catherine Harwood, Pascal Meier, Kairbaan M. Hodivala-Dilke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract The overexpression of the protein tyrosine kinase, Focal adhesion kinase (FAK), in endothelial cells has implicated its requirement in angiogenesis and tumour growth, but how pericyte FAK regulates tumour angiogenesis is unknown. We show tha
Externí odkaz:
https://doaj.org/article/327b0c1e155a4263840ab94acda7cb38
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 2, Pp n/a-n/a (2020)
Pathological angiogenesis contributes to tumour progression as well as to chronic inflammatory diseases. In this issue of EMBO Molecular Medicine, Esteban and co‐workers identify endothelial cell MT1‐MMP as a key regulator of intussusceptive angi
Externí odkaz:
https://doaj.org/article/3acbc696ba2e4167ac0ce71b2c4c8860
Autor:
Emma L. Newport, Ana Rita Pedrosa, Alexandra Njegic, Kairbaan M. Hodivala-Dilke, José M. Muñoz-Félix
Publikováno v:
Cancers, Vol 13, Iss 20, p 5207 (2021)
Several strategies have been developed to modulate the tumour vasculature for cancer therapy including anti-angiogenesis and vascular normalisation. Vasculature modulation results in changes to the tumour microenvironment including oxygenation and im
Externí odkaz:
https://doaj.org/article/68f7e403296145e89f98cacb33b45cbe
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 1 and 2. Generation and Characterisation of ECCre+;FAKY397F/Y397F and ECCre+;FAKY861F/Y861F mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5282133926484d2f37715e73d3989246
https://doi.org/10.1158/0008-5472.22422237.v1
https://doi.org/10.1158/0008-5472.22422237.v1
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Supplementary Figure 6. Knocking down Ang-2 in B16F0s cells ablates angiogenic response in ECCre+;FAKY861F/Y861F mice in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ed9c4100bd25c2f70043fe68231339
https://doi.org/10.1158/0008-5472.22422225.v1
https://doi.org/10.1158/0008-5472.22422225.v1
Autor:
Moritz Felcht, Hellmut G. Augustin, Kairbaan M. Hodivala-Dilke, Sergij Goerdt, Markus Thomas, Jochen Utikal, Cyrill Géraud, Dorothee Terhardt, Louise E. Reynolds, Nicolas Gengenbacher, Anja Gampp, Benjamin Schieb, Carolin Mogler, Corinne Hübers, Mahak Singhal, Ashik Ahmed Abdul Pari
The angiopoietin (Angpt)–TIE signaling pathway controls vascular maturation and maintains the quiescent phenotype of resting vasculature. The contextual agonistic and antagonistic Tie2 ligand ANGPT2 is believed to be exclusively produced by endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59e3921bd8e86136df6666680597eaf7
https://doi.org/10.1158/0008-5472.c.6511466.v1
https://doi.org/10.1158/0008-5472.c.6511466.v1
Autor:
Moritz Felcht, Hellmut G. Augustin, Kairbaan M. Hodivala-Dilke, Sergij Goerdt, Markus Thomas, Jochen Utikal, Cyrill Géraud, Dorothee Terhardt, Louise E. Reynolds, Nicolas Gengenbacher, Anja Gampp, Benjamin Schieb, Carolin Mogler, Corinne Hübers, Mahak Singhal, Ashik Ahmed Abdul Pari
This file consists of supplementary figures (SF) 1-11 consisting of: SF1: Melanoma cells express ANGPT2 (A-F). SF2: Melanoma cell-expressed Angpt2 does not modulate tumor cell proliferation (A-B). SF3: Tumor cell knockdown of Angpt2 does not impact g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449cc8e11f6161b45bdcc4084ff2d5e3
https://doi.org/10.1158/0008-5472.22423301
https://doi.org/10.1158/0008-5472.22423301
Autor:
Kairbaan M. Hodivala-Dilke, Thomas Iskratsch, Maddy Parsons, Bryan Serrels, Bernardo Tavora, Silvia Batista, Annika N. Alexopoulou, Vassiliki Kostourou, Delphine M. Lees, Isabelle Fernandez, Paraskivi Natalia Georgiou, Louise E. Reynolds, Edward P. Carter, Jesus Gomez-Escudero, Natalia Bodrug, Ana-Rita Pedrosa
Expression of focal adhesion kinase (FAK) in endothelial cells (EC) is essential for angiogenesis, but how FAK phosphorylation at tyrosine-(Y)397 and Y861 regulate tumor angiogenesis in vivo is unknown. Here, we show that tumor growth and angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eee9a002e76a2569618268b1a0af530
https://doi.org/10.1158/0008-5472.c.6511158.v1
https://doi.org/10.1158/0008-5472.c.6511158.v1
Supplementary Figure 1 from Antibody against Junctional Adhesion Molecule-C Inhibits Angiogenesis and Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b496e361a010636f9c027b2881bcf84
https://doi.org/10.1158/0008-5472.22363541.v1
https://doi.org/10.1158/0008-5472.22363541.v1