Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kaiqun Li"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Nasopharyngeal carcinoma (NPC) poses a significant health burden in specific regions of Asia, and some of NPC patients have bone metastases at the time of initial diagnosis. Bone metastasis can cause pathologic fractures and pain,
Externí odkaz:
https://doaj.org/article/81a708c571a94299bd412251f6f0c31c
Autor:
Zhuang Cui, Hangtian Wu, Ye Xiao, Ting Xu, Junjie Jia, Hancheng Lin, Rongmin Lin, Kun Chen, Yihuang Lin, Kaiqun Li, Xiaohu Wu, Changjun Li, Bin Yu
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract The mechanisms that coordinate the shift from joint homeostasis to osteoarthritis (OA) remain unknown. No pharmacological intervention can currently prevent the progression of osteoarthritis. Accumulating evidence has shown that subchondral
Externí odkaz:
https://doaj.org/article/868faed5010e419cbe5b8962289ad9b5
Autor:
Kaiqun Li, Ye Deng, Ganming Deng, Pengyu Chen, Yutian Wang, Hangtian Wu, Zhiguo Ji, Zilong Yao, Xianrong Zhang, Bin Yu, Kairui Zhang
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Hypercholesterolemia increases the risk of tendon pain and tendon rupture. Tendon-derived stem cells (TDSCs) play a vital role in the development of tendinopathy. Our previous research found that high cholesterol inhibits tendon-r
Externí odkaz:
https://doaj.org/article/c1aa9242a48440cfb22c522cc781d5b7
Autor:
Guanzhi Li, Ye Deng, Kaiqun Li, Yuchen Liu, Ling Wang, Zhiyong Wu, Chao Chen, Kairui Zhang, Bin Yu
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2265 (2022)
Heterotopic ossification (HO) is defined as the generation of pathological ectopic bony structures in soft tissues, but the molecular mechanisms of tendon HO are not fully revealed. Hedgehog (Hh) signalling is reportedly critical in hereditary HO. Ou
Externí odkaz:
https://doaj.org/article/32cc23dd20f845b9bb6a6f2f25088c73
Autor:
Yutian Wang, Yihuang Lin, Caiyu Cheng, Pengyu Chen, Ping Zhang, Hangtian Wu, Kaiqun Li, Ye Deng, Jikun Qian, Xianrong Zhang, Bin Yu
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/4a53243a00dd415281e9aae37af64a7d
Autor:
Yutian Wang, Yihuang Lin, Caiyu Cheng, Pengyu Chen, Ping Zhang, Hangtian Wu, Kaiqun Li, Ye Deng, Jikun Qian, Xianrong Zhang, Bin Yu
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Staphylococcus aureus (S. aureus) infection-induced osteomyelitis is a great challenge in clinic treatment. Identification of the essential genes and biological processes that are specifically changed in mononuclear cells at an early stage of S. aure
Externí odkaz:
https://doaj.org/article/df6d5f09f7bd4d9594dd64ed15eb16c0
Autor:
Wenjiao Wu, Dongguo Lin, Xintian Shen, Fangfang Li, Yuxin Fang, Kaiqun Li, Tianrong Xun, Guang Yang, Jie Yang, Shuwen Liu, Jian He
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138426 (2015)
Influenza A viral (IAV) fusion peptides are known for their important role in viral-cell fusion process and membrane destabilization potential which are compatible with those of antimicrobial peptides. Thus, by replacing the negatively or neutrally c
Externí odkaz:
https://doaj.org/article/6deff2c9a2244a27980af57791e5ee38
PD-1/PD-L1 blockade is a potent adjuvant in treatment of Staphylococcus aureus osteomyelitis in mice
Autor:
Kaiqun Li, Yuhui Chen, Yihuang Lin, Guangyan Zhang, Jianwen Su, Xiaohu Wu, Caiyu Cheng, Yutian Wang, Bin Yu, Xianrong Zhang
Publikováno v:
Molecular Therapy. 31:174-192
There is no effective therapy for implant-associated Staphylococcus aureus osteomyelitis, a devastating complication after orthopedic surgery. An immune-suppressive profile with up-regulated programmed cell death 1/programmed death ligand 1 (PD-1/PD-
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36683- (2024)
Purpose: To investigate sex-specific differences in associations of abdominal obesity indexes, systemic factors, and diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) subjects with normal body mass index (BMI). Methods: This cross-sectiona
Externí odkaz:
https://doaj.org/article/b0ff2c047fe54d91857023f82233b8b1
Autor:
Kaiqun Li, Zilong Yao, Caiyu Cheng, Ting Xu, Bin Yu, Hangtian Wu, Zhuang Cui, Xianrong Zhang, Yu Chai, Xiaohu Wu, Zhigang Chen, Peisheng Chen, Yutian Wang, Yanjun Hu, Hongan Zhang, Jianwen Su
Publikováno v:
Journal of Cellular Physiology. 235:8653-8666
Osteoarthritis (OA), a disease of the entire joint, is characterized by abnormal bone remodeling and coalescent degradation of articular cartilage. We have previously found that elevated levels of H-type vessels in subchondral bone correlate with OA