Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kaio Maciel de Santiago-Silva"'
Autor:
Kaio Maciel de Santiago-Silva, Priscila Goes Camargo, Larissa Esteves Carvalho Constant, Stephany da Silva Costa, Giovanna Barbosa Frensel, Diego Allonso, Gerson Nakazato, Camilo Henrique da Silva Lima, Marcelle de Lima Ferreira Bispo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Scientists and researchers have been searching for drugs targeting the main protease (Mpro) of SARS-CoV-2, which is crucial for virus replication. This study employed a virtual screening based on molecular docking to identify benzoylguanidin
Externí odkaz:
https://doaj.org/article/ce15e21da1944d63a519ca082f6675a0
Autor:
Kaio Maciel de Santiago-Silva, Bruna Taciane da Silva Bortoleti, Laudicéa do Nascimento Oliveira, Fernanda Lima de Azevedo Maia, Joyce Cristina Castro, Ivete Conchon Costa, Danielle Bidóia Lazarin, James L. Wardell, Solange M. S. V. Wardell, Magaly Girão Albuquerque, Camilo Henrique da Silva Lima, Wander Rogério Pavanelli, Marcelle de Lima Ferreira Bispo, Raoni Schroeder B. Gonçalves
Publikováno v:
Antibiotics, Vol 11, Iss 10, p 1402 (2022)
Leishmaniasis is a neglected tropical disease caused by Leishmania species. Available therapeutic options have several limitations. The drive to develop new, more potent, and selective antileishmanial agents is thus a major goal. Herein we report the
Externí odkaz:
https://doaj.org/article/59bfd238fa0f49c19af2afc8b76a5b47
Autor:
Marcieli Fabris, Kaio Maciel De Santiago-Silva, Priscila Goes Camargo, Marcelle Bispo, Mariana Luiza Silva
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 23:981-988
Abstract: CYP1B1 plays an essential role in cancer's pathogenesis since it activates procarcinogens. Significantly, this enzyme catalyzes the hydroxylation of 17β-estradiol, leading to carcinogenic metabolites involved in carcinogenesis and cancer p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317e9ec63b2c6d6c920d6cce25071a0a
https://doi.org/10.2174/1871520623666230119103914
https://doi.org/10.2174/1871520623666230119103914
Publikováno v:
Medicinal Chemistry. 19:2-9
Abstract: Leishmaniasis is a neglected tropical disease widely distributed worldwide, caused by parasitic protozoa of the genus Leishmania. Despite representing a significant public health problem, the therapeutic options are old, with several report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed02b65e89e3ebc13997223e67ea54a4
https://doi.org/10.2174/1573406418666220713145446
https://doi.org/10.2174/1573406418666220713145446
Autor:
Ana Paula Sotero, Alexandre Orsato, Camilo Lima, Kaio Maciel De Santiago-Silva, Carla Cristina Perez, Priscila Goes Camargo, Marcelle Bispo, Gerson Nakazato, Gabriel Felix da Silva Gomes
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-14
The coronavirus disease-2019 (COVID-19) pandemic, caused by the novel coronavirus severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), became the highest public health crisis nowadays. Although the use of approved vaccines for emergency immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2546f5456abd31897d6ffe4ab002ca4
https://doi.org/10.1080/07391102.2022.2123396
https://doi.org/10.1080/07391102.2022.2123396
Autor:
Thaysa Bazana Bessegato, José Renato Silva, Kaio Maciel de Santiago Silva, Emely Osti Zanon, Jaqueline Camisa, Giselle Nobre Costa
Publikováno v:
Bioscience Journal, Vol 35, Iss 2 (2019)
Functional foods are those that, beyond basic nutrition, promote health benefits. This study aimed to produce a fermented beverage from a water-soluble soybean extract and low-lactose semi-skimmed milk. The beverage was prepared using a blend (v/v) c
Externí odkaz:
https://doaj.org/article/f48c5470da5449688dcb5e5d81776f5a
Autor:
Marcelle de Lima Ferreira Bispo, Kaio Maciel de Santiago-Silva, Gabriel Felix da Silva Gomes, Carla Cristina Perez, Camilo Henrique da Silva Lima
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 23
Abstract: Leishmaniases are infectious diseases caused by flagellated protozoan parasites belonging to the genus Leishmania that infect cells of the mononuclear phagocytic system. These parasites are transmitted to humans by biting an infected female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51bb4debf59a01ed6b5db365375221ce
https://doi.org/10.2174/1389557523666230127125058
https://doi.org/10.2174/1389557523666230127125058
Autor:
Wander Rogério Pavanelli, Milena Menegazzo Miranda-Sapla, Bruna Taciane da Silva Bortoleti, Kaio Maciel de Santiago-Silva, Fernando Macedo, Marcelle de Lima Ferreira Bispo, Camilo Henrique da Silva Lima, Ivete Conchon Costa, Tiago Oliveira Brito
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:11495-11510
In this report, we describe the synthesis and evaluation of nine N1,N2-disubstituted-benzoylguanidines against promastigotes and amastigotes forms of Leishmania amazonensis. The derivatives 2g and ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36fb28157d6417a2456656d29c299b17
https://doi.org/10.1080/07391102.2021.1959403
https://doi.org/10.1080/07391102.2021.1959403
Autor:
Gabriel Felix da Silva Gomes, Priscila Goes Camargo, Kaio Maciel de Santiago-Silva, Helena Tiemi Suzukawa, Ana Paula Sotero da Silva Ribeiro, Alexandre Orsato, Gerson Nakazato, Sueli Fumie Yamada-Ogatta, Ligia Carla Faccin-Galhardi, Camilo Henrique da Silva Lima, Marcelle de Lima Ferreira Bispo, Carla Cristina Perez
COVID-19, a disease caused by SARS-CoV-2, was declared a pandemic in 2020 and created a global crisis in health systems, with more than 545 million confirmed cases and 6.33 million deaths. In this sense, this work aims to identify possible inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65eca2c1cb8a0cb86f35a8e9c45d9677
Autor:
Kaio Maciel de, Santiago-Silva, Bruna Taciane da Silva, Bortoleti, Tiago de Oliveira, Brito, Ivete Conchon, Costa, Camilo Henrique da Silva, Lima, Fernando, Macedo, Milena Menegazzo, Miranda-Sapla, Wander Rogério, Pavanelli, Marcelle de Lima Ferreira, Bispo
Publikováno v:
Journal of biomolecular structuredynamics. 40(22)
In this report, we describe the synthesis and evaluation of nine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57dd41bf4777a5231234c0a051a2b4a5
https://pubmed.ncbi.nlm.nih.gov/34355671
https://pubmed.ncbi.nlm.nih.gov/34355671