Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kainath Durre"'
Publikováno v:
The Journal of Immunology. 202:119.22-119.22
RSV infection in early life predisposes to asthma later in life. Role of aberrant immune responses to childhood viral infections is well documented. Involvement of myeloid (mDC) and plasmacytoid (pDC) Dendritic Cells (DC) and Natural Killer T-cells (
Publikováno v:
The Journal of Immunology. 198:203.24-203.24
RSV bronchiolitis and pneumonia causes significant mortality in young infants every year. The survivors become susceptible to asthma. In our present study, using a mouse model of BALB/C and NKT−/− mice, we examined the pulmonary responses to RSV
Publikováno v:
The Journal of Immunology. 196:191.10-191.10
RSV bronchiolitis and pneumonia in infancy is known to be associated with increased susceptibility to asthma. This phenomenon is characterized by a hyper reactive airway with a predominant Th2 response and a skewed dendritic cell (DC) polarization, w
Publikováno v:
The FASEB Journal. 22
Publikováno v:
The Journal of Immunology. 192:118.18-118.18
RSV bronchiolitis is an important cause of pediatric hospitalization, which often leads to developing asthma in later life. Studies have indicated a Th2 skewed polarization of the lung environment in these children, which can be modulated by exogenou
Publikováno v:
The Journal of Immunology. 190:124.27-124.27
Respiratory Syncitial Virus (RSV)-induced bronchiolitis-pneumonia during early infancy predisposes asthma in later life. Augmented Th2 response and skewed polarization of Dendritic cells (DC) towards plasmacytoid DC (pDC) are associated. In addition,
Publikováno v:
The Journal of Immunology. 188:175.5-175.5
Survivors of RSV bronchiolitis and pneumonia develop increased susceptibility to asthma. We showed that skewed polarization of dendritic cells (DC) towards plasmacytoid DC (pDC) in the pups in response to RSV is inhibited by exogenous administration
Publikováno v:
The Journal of Immunology. 186:147.28-147.28
Pediatric post-RSV infection associated bronchial asthma is known to be mediated via an enhanced pulmonary Th2 response. However, adult RSV infection is not known to be associated with this pathology. Further, osteopontin and NKT cell have been repor
Publikováno v:
The Journal of Immunology. 184:37.46-37.46
RSV bronchiolitis and pneumonia during early infancy is associated with increased susceptibility to asthma; and is characterized by a hyper-responsiveness airway and a predominant Th2 response. Using a BALB/C neonatal mouse model we have observed a s
Publikováno v:
The Journal of Immunology. 182:131.6-131.6
RSV infection in early infancy makes individuals susceptible to develop asthma in later life due to airway hyper-responsiveness (AHR) to innocuous antigens, which is characterized by enhanced Th2 responses. Using a neonatal mouse model, we investigat