Zobrazeno 1 - 10
of 422
pro vyhledávání: '"Kaiming Zhang"'
Autor:
Pengfei Fan, Mengmeng Sun, Xinghai Zhang, Huajun Zhang, Yujiao Liu, Yanfeng Yao, Ming Li, Ting Fang, Bingjie Sun, Zhengshan Chen, Xiangyang Chi, Li Chen, Cheng Peng, Zhen Chen, Guanying Zhang, Yi Ren, Zixuan Liu, Yaohui Li, Jianmin Li, Entao Li, Wuxiang Guan, Shanshan Li, Rui Gong, Kaiming Zhang, Changming Yu, Sandra Chiu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The Hendra and Nipah viruses (HNVs) are highly pathogenic pathogens without approved interventions for human use. In addition, the interaction pattern between the attachment (G) and fusion (F) glycoproteins required for virus entry remains u
Externí odkaz:
https://doaj.org/article/14e8c25791854095a7cb85b5e6910684
Autor:
Xinyan Chen, Anat Raiff, Shanshan Li, Qiong Guo, Jiahai Zhang, Hualin Zhou, Richard T. Timms, Xuebiao Yao, Stephen J. Elledge, Itay Koren, Kaiming Zhang, Chao Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The E3 ligase-degron interaction determines the specificity of the ubiquitin‒proteasome system. We recently discovered that FEM1B, a substrate receptor of Cullin 2-RING ligase (CRL2), recognizes C-degrons containing a C-terminal proline. B
Externí odkaz:
https://doaj.org/article/ffbc3ea809874fc5b76a3798f02b99ec
Autor:
Li Chen, Mengmeng Sun, Huajun Zhang, Xinghai Zhang, Yanfeng Yao, Ming Li, Kangyin Li, Pengfei Fan, Haiwei Zhang, Ye Qin, Zhe Zhang, Entao Li, Zhen Chen, Wuxiang Guan, Shanshan Li, Changming Yu, Kaiming Zhang, Rui Gong, Sandra Chiu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Nipah virus (NiV) is a World Health Organization priority pathogen and there are currently no approved drugs for clinical immunotherapy. Through the use of a naïve human phage-displayed Fab library, two neutralizing antibodies (NiV41 and Ni
Externí odkaz:
https://doaj.org/article/8960ea1cd51c4e3a95f8fabca3b7e65c
Autor:
Hailei Zhang, Bo Zhang, Chongyang Cai, Kaiming Zhang, Yu Wang, Yuan Wang, Yanmin Yang, Yonggang Wu, Xinwu Ba, Richard Hoogenboom
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Developing X-ray scintillators that are water-dispersible, compatible with polymeric matrices, and processable to flexible substrates is an important challenge. Herein, Tb3+-doped Na5Lu9F32 is introduced as an X-ray scintillating material wi
Externí odkaz:
https://doaj.org/article/80954e4743ea474da034677682e16d71
Autor:
Qingshan Chen, Fenglin Gao, Junwan Wu, Kaiming Zhang, Tian Du, Yuhong Chen, Ruizhao Cai, Dechang Zhao, Rong Deng, Jun Tang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Background Mitochondrial outer membrane permeabilisation (MOMP) plays a pivotal role in cellular death and immune activation. A deeper understanding of the impact of tumour MOMP on immunity will aid in guiding more effective immunotherapeuti
Externí odkaz:
https://doaj.org/article/43ecb89d02374b6f822f97327af205c5
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Histamine receptors are a group of G protein-coupled receptors (GPCRs) that play important roles in various physiological and pathophysiological conditions. Antihistamines that target the histamine H1 receptor (H1R) have been widely used to
Externí odkaz:
https://doaj.org/article/f965e3627ca64750b595e5c24d924fd6
Autor:
Shanshan Li, Kan-Yen Hsieh, Chiao-I Kuo, Tzu-Chi Lin, Szu-Hui Lee, Yi-Ru Chen, Chun-Hsiung Wang, Meng-Ru Ho, See-Yeun Ting, Kaiming Zhang, Chung-I Chang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Many AAA+ (ATPases associated with diverse cellular activities) proteins function as protein or DNA remodelers by threading the substrate through the central pore of their hexameric assemblies. In this ATP-dependent translocating state, the
Externí odkaz:
https://doaj.org/article/9bf22aa7817641b7b47e58b76cb20d3a
Autor:
Yi Zhou, Yan Wang, Jun Tang, Rong Deng, Dechang Zhao, Wenqing Zhong, Kaiming Zhang, Jialu Shan, Ruizhao Cai, Tian Du, Qingshan Chen
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Objective To investigate the prognostic impact of initial lung cancer (LC) on second primary breast cancer after LC (LC-BC) and further develop a nomogram for predicting the survival of patients.Methods All patients diagnosed with LC-BC and first pri
Externí odkaz:
https://doaj.org/article/53645ef92b68419c86b3f1a32dd7cab6
Autor:
Jie Deng, Xianyang Fang, Lin Huang, Shanshan Li, Lilei Xu, Keqiong Ye, Jinsong Zhang, Kaiming Zhang, Qiangfeng Cliff Zhang
Publikováno v:
Fundamental Research, Vol 3, Iss 5, Pp 727-737 (2023)
RNA molecules serve a wide range of functions that are closely linked to their structures. The basic structural units of RNA consist of single- and double-stranded regions. In order to carry out advanced functions such as catalysis and ligand binding
Externí odkaz:
https://doaj.org/article/4828766ef7204c199ec89812e92426df
Publikováno v:
eLife, Vol 12 (2024)
Precursor ribosomal RNA (pre-rRNA) processing is a key step in ribosome biosynthesis and involves numerous RNases. A HEPN (higher eukaryote and prokaryote nucleotide binding) nuclease Las1 and a polynucleotide kinase Grc3 assemble into a tetramerase
Externí odkaz:
https://doaj.org/article/d13151944a24497ca72e50ec1a8350c2